anatomy of a scientific discovery the race to find the body s own morphine

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Anatomy Of A Scientific Discovery

Author : Jeff Goldberg
ISBN : 9781628734263
Genre : Science
File Size : 57. 19 MB
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The “fascinating” story of the global scientific race to discover and unlock the power of endorphins—the body’s own morphine (The New Yorker). In 1973, scientists John Hughes and Hans Kosterlitz were studying pig brains in an underfunded laboratory in Aberdeen, Sweden. During their research, the duo discovered a non-addictive narcotic chemical. What if they could find a similar chemical in humans? If human brains also had this chemical and they could somehow isolate it, perhaps Hughes and Kosterlitz could find a way to help the world begin to heal itself. Their work would lead them to discover endorphins, the body’s own natural morphine and the chemical that makes it possible to feel both pain and pleasure. Their findings made Hughes and Kosterlitz overnight celebrities. Soon, scientists all over the world were rushing to study the human brain and its endorphins. In a few years, scientists would use the team’s initial research to link endorphins to drug addiction, runner’s high, appetite control, sexual response, and mental illnesses such as depression and schizophrenia. In Anatomy of a Scientific Discovery, Jeff Goldberg describes Hughes and Kosterlitz’s lives before, during, and after their historic and scientific breakthrough. He also reveals the brutal competition between drug companies as they raced to find a way to cash in on this monumental discovery.

The Spark Of Life Electricity In The Human Body

Author : Frances Ashcroft
ISBN : 9780393089547
Genre : Science
File Size : 86. 3 MB
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“A gem that sparkles.”—William Bynum, Wall Street Journal What happens during a heart attack? Can someone really die of fright? What is death, anyway? How does electroshock treatment affect the brain? What is consciousness? The answers to these questions lie in the electrical signals constantly traveling through our bodies, driving our thoughts, our movements, and even the beating of our hearts. The history of how scientists discovered the role of electricity in the human body is a colorful one, filled with extraordinary personalities, fierce debates, and brilliant experiments. Moreover, present-day research on electricity and ion channels has created one of the most exciting fields in science, shedding light on conditions ranging from diabetes and allergies to cystic fibrosis, migraines, and male infertility. With inimitable wit and a clear, fresh voice, award-winning researcher Frances Ashcroft weaves together compelling real-life stories with the latest scientific findings, giving us a spectacular account of the body electric.

Leverage Your Laziness

Author : Jeff Goldberg
ISBN : 9781937879150
Genre : Business & Economics
File Size : 73. 42 MB
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Jeff Goldberg and Steve Bookbinder combine their wit, intellect, and common sense in this entertaining, data packed instructional manual. They draw on their personal insight, diversified experiences, and passion for life coaching in the writing and production of Leverage Your Laziness! In this collaboration they introduce an approach designed to use leverage and laziness as a strategy for attaining effective performance with the least work and the added bonus of sensing the enjoyment of accomplishment. Steve helps the reader discover how to recognize and utilize their strongest strengths in their personal strategy for success. Jeff introduces keys to focus on those things you enjoy most in your work to increase your personal productivity with the least effort. Sixteen principles, dozens of motivational quotes from dozens of recognized leaders, and the opportunity for individual readers to get specific in applying these principles personally make up the format of this humorous, practical, and powerful guidebook. Concise, and compact, yet comprehensive Leverage Your Laziness! is an important tool for the established entrepreneur, for successful leaders, for life coaches, and for those who "wanna be" rich and famous.

Bird At The Buzzer

Author : Jeff Goldberg
ISBN : 9780803235403
Genre : Education
File Size : 83. 17 MB
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On March 6, 2001, the top two women’s college basketball teams in the nation, UConn and Notre Dame, played what was arguably the greatest game in the history of the sport. When UConn’s Sue Bird hit a twelve-foot pull-up jumper at the buzzer over national player of the year Ruth Riley in the Big East Tournament championship game, it marked the end of an epic contest that featured five future Olympians and eight first-round WNBA selections. Bird at the Buzzer re-creates this unique season with a detailed account of the games that led up to—and beyond—the tournament finale; profiles of the two coaches, UConn’s Geno Auriemma and Notre Dame’s Muffet McGraw; close-ups of the players who made the year so memorable; and, finally, an in-depth recap of the game worthy of being designated ESPN’s first-ever women’s basketball “Instant Classic.” Author Jeff Goldberg shows us the drama on the court and behind the scenes as the big game pitted Riley and the upstarts from Notre Dame against what many believed was the most talented team in UConn history, under Hall of Fame coach Auriemma. A see-saw affair in which neither team led by more than eight points, the 2001 Big East championship game encapsulates the quintessential inside story of the individual talents and skills, team spirit and smarts, and the moment-by-moment realities of college athletics that made this season a snapshot of sports at its finest.

Smoking Ears And Screaming Teeth A Celebration Of Scientific Eccentricity And Self Experimentation

Author : Trevor Norton
ISBN : 9781605988504
Genre : Science
File Size : 23. 38 MB
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A witty celebration of the great eccentrics who have performed dangerous scientific experiments on themselves for the benefit of humankind. Many scientists have followed the advice of the great Victorian doctor Jack Haldane to “never experiment on an animal if a man will do” and “never ask anyone to do anything you wouldn’t do yourself.” He and his father inhaled poisonous gasses to test the efficacy of the prototype gas mask they had invented. When breathing gasses under pressure he suffered the smoking ears and screaming teeth of the title. The stories in Norton’s new book are astonishing, disturbing or absurd. The zoologist Frank Buckland made a concentrated effort to widen the nation’s diet by personally testing everything that crossed his path, from boiled elephant’s trunk to slug soup. Some medics deliberately contracted deadly blood diseases in the hope of finding cures. Then there was the surgeon who was fired and subsequently won the Nobel Prize for thrusting a catheter into his own beating heart.

Flowers In The Blood

Author : Jeff Goldberg
ISBN : 9781628738995
Genre : History
File Size : 30. 2 MB
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The ultimate book on the incredible, and complex history of opium throughout the world. Flowers in the Blood lifts the veil of mystery that has surrounded opium down through the ages. Inside, discover: Why a three-thousand-year-old statue of a Greek goddess was crowned with poppies The formulas for Hippocrates’s ancient opium remedies Why the Islamic councils of the wise vilified hashish but venerated opium What really provoked the Opium Wars in China Why John Jacob Astor quit the opium trade The unique role played by Chinese opium in the birth of the American labor movement Opium has played a dramatic and varied role in human history, inspiring religious veneration, scientific exploration, the bitterest rancor, and the most fanciful ecstasy. Now, authors Jeff Goldberg and Dean Latimer have provided a complete, insightful history of opium. Along the way, the authors provide details of the addictions of S. T. Coleridge, Thomas De Quincey, and other literary opium-eaters of the nineteenth century, as well as chronicling the progress of antidrug laws and the ongoing search for an addiction cure. Originally published in 1981, this edition of Flowers in the Blood has been updated with a new preface by Goldberg. At times disconcerting—raising serious questions about attitudes and approaches toward powerful drugs and their control—Flowers in the Blood is an essential addition to the literature of opium, and a wide-awake look at the stuff that dreams (and nightmares) are made of. Skyhorse Publishing, as well as our Arcade imprint, are proud to publish a broad range of books for readers interested in history--books about World War II, the Third Reich, Hitler and his henchmen, the JFK assassination, conspiracies, the American Civil War, the American Revolution, gladiators, Vikings, ancient Rome, medieval times, the old West, and much more. While not every title we publish becomes a New York Times bestseller or a national bestseller, we are committed to books on subjects that are sometimes overlooked and to authors whose work might not otherwise find a home.

The Emperor Of Scent

Author : Chandler Burr
ISBN : 1588362604
Genre : Biography & Autobiography
File Size : 88. 42 MB
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For as long as anyone can remember, a man named Luca Turin has had an uncanny relationship with smells. He has been compared to the hero of Patrick Süskind’s novel Perfume, but his story is in fact stranger, because it is true. It concerns how he made use of his powerful gifts to solve one of the last great mysteries of the human body: how our noses work. Luca Turin can distinguish the components of just about any smell, from the world’s most refined perfumes to the air in a subway car on the Paris metro. A distinguished scientist, he once worked in an unrelated field, though he made a hobby of collecting fragrances. But when, as a lark, he published a collection of his reviews of the world’s perfumes, the book hit the small, insular business of perfume makers like a thunderclap. Who is this man Luca Turin, they demanded, and how does he know so much? The closed community of scent creation opened up to Luca Turin, and he discovered a fact that astonished him: no one in this world knew how smell worked. Billions and billions of dollars were spent creating scents in a manner amounting to glorified trial and error. The solution to the mystery of every other human sense has led to the Nobel Prize, if not vast riches. Why, Luca Turin thought, should smell be any different? So he gave his life to this great puzzle. And in the end, incredibly, it would seem that he solved it. But when enormously powerful interests are threatened and great reputations are at stake, Luca Turin learned, nothing is quite what it seems. Acclaimed writer Chandler Burr has spent four years chronicling Luca Turin’s quest to unravel the mystery of how our sense of smell works. What has emerged is an enthralling, magical book that changes the way we think about that area between our mouth and our eyes, and its profound, secret hold on our lives. From the Hardcover edition.

Molecules Of Emotion

Author : Candace Pert
ISBN : 9781471109706
Genre : Science
File Size : 53. 78 MB
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Why do we feel the way we feel? How do our thoughts and emotions affect our health? Are our bodies and minds distinct from each other or do they function together as part of an interconnected system? In MOLECULES OF EMOTION, neuroscientist Candace Pert provides startling and decisive answers to these long-debated questions, establishing the biomolecular basis for our emotions and explaining these new scientific developments in a clear and accessible way. Her pioneering research on how the chemicals inside us form a dynamic information network, linking mind and body, is not only provocative, it is revolutionary. In her groundbreaking book, Candace Pert offers a new scientific understanding of the power of our minds and our feelings to affect our health and well-being.

Human Accomplishment

Author : Charles Murray
ISBN : 9780061745676
Genre : History
File Size : 86. 71 MB
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A sweeping cultural survey reminiscent of Barzun's From Dawn to Decadence. "At irregular times and in scattered settings, human beings have achieved great things. Human Accomplishment is about those great things, falling in the domains known as the arts and sciences, and the people who did them.' So begins Charles Murray's unique account of human excellence, from the age of Homer to our own time. Employing techniques that historians have developed over the last century but that have rarely been applied to books written for the general public, Murray compiles inventories of the people who have been essential to the stories of literature, music, art, philosophy, and the sciences—a total of 4,002 men and women from around the world, ranked according to their eminence. The heart of Human Accomplishment is a series of enthralling descriptive chapters: on the giants in the arts and what sets them apart from the merely great; on the differences between great achievement in the arts and in the sciences; on the meta-inventions, 14 crucial leaps in human capacity to create great art and science; and on the patterns and trajectories of accomplishment across time and geography. Straightforwardly and undogmatically, Charles Murray takes on some controversial questions. Why has accomplishment been so concentrated in Europe? Among men? Since 1400? He presents evidence that the rate of great accomplishment has been declining in the last century, asks what it means, and offers a rich framework for thinking about the conditions under which the human spirit has expressed itself most gloriously. Eye-opening and humbling, Human Accomplishment is a fascinating work that describes what humans at their best can achieve, provides tools for exploring its wellsprings, and celebrates the continuing common quest of humans everywhere to discover truths, create beauty, and apprehend the good.

Philosophy Of Osteopathy

Author : Andrew Taylor Still
ISBN : STANFORD:24504228988
Genre : Osteopathic Medicine
File Size : 32. 47 MB
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