animal cell bioreactors biotechnology series

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Animal Cell Bioreactors

Author : Chester S. Ho
ISBN : 9781483289472
Genre : Science
File Size : 48. 79 MB
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Animal Cell Bioreactors provides an introduction to the underlying principles and strategies in the in vitro cell culture biotechnology. It addresses engineering aspects such as mass transfer, instrumentation, and control ensuring successful design and operation of animal cell bioreactors. The goal is to provide a comprehensive analysis and review in the advancement of the bioreactor systems for large-scale animal cell cultures. The book is organized into four parts. Part I traces the historical development of animal cell biotechnology. It presents examples of work in progress that seeks to make animal cell biotechnology processes as productive on a cost per unit of product basis as that achieved by other microbial systems. Part II includes chapters dealing with the implications of cell biology in animal cell biotechnology; protein-bound oligosaccharides and their structures; the development of serum-free media and its use in the production of biologically active substances; and the metabolism of mammalian cells. Part III focuses on animal cell cultivation, covering topics such as the fixed bed immobilized culture; three-dimensional microcarriers; and hydrodynamic phenomena in microcarrier cultures. Part IV discusses the design, operation, and control of animal cell bioreactors.

Animal Cell Biotechnology

Author : R. E. Spier
ISBN : 9780126575569
Genre : Medical
File Size : 72. 34 MB
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There has been a dramatic increase in the perception of the value of animal cell biotechnology to the research and manufacturing communities in recent years. This volume seeks to keep the reader up-to-date with this progress. This sixth and final volume in the series concentrates on the biology of animal cells in culture, giving special attention to the relationship between biology and the ability to use such cells productively. As the search continues for greater productivity, there is a need to understand the switches within cells that control expression. Additional abilities to manipulate those switches in a controllable manner are also required. In the last five years, considerable progress has been made in the elucidation of the mechanisms for cell signaling and control of gene expression. The 13 chapters of this volume are devoted to these subjects and to techniques in areas of particular concern in manufacturing circles. The achievements in the field to date are described in this book, which, together with its five companion volumes in the series, will provide a building block for the future development of animal cell biotechnology.

Animal Cell Biotechnology

Author : Ralf Pörtner
ISBN : 9781588296603
Genre : Science
File Size : 74. 24 MB
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The second edition of this book constitutes a comprehensive manual of new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture considering the whole cascade from lab to final production. The chapters are written by world-renowned experts and the volume’s five parts reflect the processes required for different stages of production. This book is a compendium of techniques for scientists in both industrial and research laboratories that use mammalian cells for biotechnology purposes.

Bioreactors In Biotechnology

Author : Alan H. Scragg
ISBN : UOM:39015024793948
Genre : Science
File Size : 30. 36 MB
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Animal Cell Biotechnology

Author : Hansjörg Hauser
ISBN : 9783110278965
Genre : Science
File Size : 50. 9 MB
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This book introduces the fundamental principles and practical application of techniques used in the scalable production of proteins and virus-based gene-therapeutic products with animal cell cultures. The book reviews a broad spectrum of subjects relevant to biologics production, including the creation of cell lines, a survey of functional genomics for cell lines and processes, and advances in upstream and downstream process development. It is an essential reference for all those working in the biotechnology field both from an academic and industrial standpoint.

Animal Cells As Bioreactors

Author : Terence Cartwright
ISBN : 0521412587
Genre : Medical
File Size : 48. 59 MB
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Because of their complexity, the new generation of genetically engineered protein drugs can only be made by biotechnological methods, using cultures of animal cells. This book covers all aspects of the technologies needed to turn animal cells into an acceptable and cost-effective tool for drug production. This includes modifying them genetically so that they produce the right product in high yield, getting them to grow reproducibly on an industrial scale, and extracting the required product from them. It also covers biological safety issues, and the verification of the chemical and biological nature of the protein drug produced. The work covers developments in all of these areas and how they all need to be integrated for the design of an effective biotechnological production process. It therefore provides a comprehensive guide to this area of biotechnology.

Production Of Biologicals From Animal Cells In Culture

Author : R. E. Spier
ISBN : 9781483165158
Genre : Medical
File Size : 31. 88 MB
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Production of Biologicals from Animal Cells in Culture reviews the state of the art in animal cell biotechnology, with emphasis on the sequence of events that occur when generating a biological from animal cells in culture. Methods that enable adjustment of nutrient feed streams into perfusion bioreactors so as to increase productivity are described. A number of issues are also addressed, such as the usefulness of the fingerprint method for cell characterization. Comprised of 135 chapters, this book begins with an overview of the problems and benefits of animal cell culture, followed by a discussion on the isolation of immortal murine macrophage cell lines. The reader is systematically introduced to the use of DNA fingerprinting to characterize cell banks; immortalization of cells with oncogenes; lipid metabolism of animal cells in culture; and energetics of glutaminolysis. Subsequent chapters explore serum-free and protein-free media; the physiology of animal cells; gene expression in animal cell systems; and animal cell bioreactors. The monitoring and assay of animal cell parameters are also considered, along with downstream processing and regulatory issues. This monograph will be of interest to students, practitioners, and investigators in the fields of microbiology and biotechnology.

Animal Cell Biotechnology

Author :
ISBN : WISC:89052220456
Genre : Cell culture
File Size : 82. 7 MB
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There has been a dramatic increase in the perception of the value of animal cell biotechnology to the research and manufacturing communities in recent years. This volume seeks to keep the reader up-to-date with this progress. This sixth and final volume in the series concentrates on the biology of animal cells in culture, giving special attention to the relationship between biology and the ability to use such cells productively. As the search continues for greater productivity, there is a need to understand the switches within cells that control expression. Additional abilities to manipulate those switches in a controllable manner are also required. In the last five years, considerable progress has been made in the elucidation of the mechanisms for cell signaling and control of gene expression. The 13 chapters of this volume are devoted to these subjects and to techniques in areas of particular concern in manufacturing circles. The achievements in the field to date are described in this book, which, together with its five companion volumes in the series, will provide a building block for the future development of animal cell biotechnology.

The Law And Strategy Of Biotechnology Patents

Author : Kenneth D. Sibley
ISBN : 9781483161938
Genre : Law
File Size : 23. 74 MB
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The Law and Strategy of Biotechnology Patents is a compendium of articles that sets to address and unravel the complexities of the laws and issues that apply to biotechnology inventions. The purpose of the book is to explain patent law, with special emphasis on the central role of patent claims, statutory subject matter, novelty, non-obviousness, disclosure considerations, and operation of the judicial system in relation to patents. The text also unveils the extent to which biotechnology merges established law with new requirements. Lawyers, inventors, researchers, technology development and transfer agents, venture capitalists, investment bankers, entrepreneurs, and researchers will find this book an important source of information and knowledge.

Biotechnology 5 Animal Cells Immunology Plant Biotechnology

Author : M. K. Sateesh
ISBN : 8122414516
Genre : Biotechnology
File Size : 40. 63 MB
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This Book Is Designed As Per The Syllabus Of Biotechnology Paper-5 Prescribed By Bangalore University And Other Indian Universities. The Book Is Divided Into Three Parts As Follows: * Animal Cell Biotechnology * Immunology * Plant BiotechnologyThe Presentation In Each Part Is Simple And Systematic. The Basic Concepts Have Been Clearly Explained And Their Functions Are Adequately Highlighted. A Few Recent Developments Have Also Been Included To Provide A Contemporary Understanding Of The Subject.

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