antibiofilm agents from diagnosis to treatment and prevention springer series on biofilms

Download Book Antibiofilm Agents From Diagnosis To Treatment And Prevention Springer Series On Biofilms in PDF format. You can Read Online Antibiofilm Agents From Diagnosis To Treatment And Prevention Springer Series On Biofilms here in PDF, EPUB, Mobi or Docx formats.

Antibiofilm Agents

Author : Kendra P. Rumbaugh
ISBN : 9783642538339
Genre : Science
File Size : 64. 91 MB
Format : PDF, ePub, Mobi
Download : 259
Read : 541

Get This Book


This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.

New Look To Phytomedicine

Author : Mohd Sajjad Ahmad Khan
ISBN : 9780128146200
Genre : Medical
File Size : 53. 40 MB
Format : PDF, ePub, Mobi
Download : 826
Read : 868

Get This Book


New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads is a compilation of in-depth information on the phytopharmaceuticals used in modern medicine for the cure and management of difficult-to-treat and challenging diseases. Readers will find cutting-edge knowledge on the use of plant products with scientific validation, along with updates on advanced herbal medicine in pharmacokinetics and drug delivery. This authoritative book is a comprehensive collection of research based, scientific validations of bioactivities of plant products, such as anti-infective, anti-diabetic, anti-cancer, immune-modulatory and metabolic disorders presented by experts from across the globe. Step-by-step information is presented on chemistry, bioactivity and the functional aspects of biologically active compounds. In addition, the pharmacognosy of plant products with mechanistic descriptions of their actions, including pathogenicity is updated with information on the use of nanotechnology and molecular tools in relation to herbal drug research. Compiles up-to-date information on the chemotherapeutics used in the treatment of infective and metabolic disorders Presents advancements in the discovery of new drugs from plants using molecular and nanotechnology tools Examines detailed information on the use of herbals agents in cancer, HIV and other ailments, including diabetes, malaria and neurological disorders

Perioperative Medical Management For Total Joint Arthroplasty

Author : Andrea Baldini
ISBN : 9783319072036
Genre : Medical
File Size : 62. 86 MB
Format : PDF, Docs
Download : 529
Read : 249

Get This Book


This volume describes the most recent medical guidelines for perioperative management in arthroplasty with the aim of facilitating excellent control of bleeding/thrombosis, pain and infection. For each area – hemostasis control, pain control and infection control – hot topics of key practical importance are discussed and contrasting perspectives are presented on controversial issues, covering the views of different practitioners and specialties. Using the information contained in this book, the practitioner will be in an excellent position to meet the principal goals of perioperative medical management. The information provided will assist in the choice of a multimodal guideline that minimizes the complication rate regarding bleeding and thromboembolism while not interfering with the patient’s recovery. Similarly, effective means of pain control and an optimized pain control protocol are discussed with a view to shortening hospital stay and achieving functional milestones that meet the patient’s expectations. Finally, host, wound and environmental factors relevant to infection and its prevention are explained, with discussion of the best means of prophylaxis, treatment and imaging. Surgeons, anesthesiologists and all medical practitioners and staff involved in the field of total hip and knee arthroplasty will find this book to be of value in their daily clinical practice. It will assist in the provision of enhanced medical management that ensures quicker recovery of the patient with fewer complications.

The Infected Total Knee Arthroplasty

Author : E. Carlos Rodríguez-Merchán
ISBN : 9783319667300
Genre : Medical
File Size : 77. 76 MB
Format : PDF, ePub, Docs
Download : 550
Read : 958

Get This Book


This book is structured in a way that guides the reader from prevention through to diagnosis and then treatment of infection following total knee arthroplasty, in each case providing state of the art information on available techniques and procedures. The section on the crucial preventive measures include guidance on preoperative optimization and skin preparation, antibiotic prophylaxis, and preoperative microbiological screening. All relevant aspects of diagnosis of infection are considered in detail, and the treatment-related section includes chapters on antibiotic suppression, arthroscopic lavage, open debridement with polyethylene exchange, one- and two-stage revision arthroplasty, and knee arthrodesis as a salvage procedure. Readers will also find clear instruction on how to proceed when all attempts to eradicate infection fail. In reflecting the latest knowledge and practice in this rapidly advancing field, the book will be an asset to all who are involved in the care of these patients.

The Therapeutic Use Of N Acetylcysteine Nac In Medicine

Author : Richard Eugene Frye
ISBN : 9789811053115
Genre : Medical
File Size : 69. 44 MB
Format : PDF, ePub, Docs
Download : 954
Read : 943

Get This Book


Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer’s disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive disorder, schizophrenia, traumatic brain injury and trichotillomania in addition to promising studies in audiology, cardiology, exercise physiology, gastroenterology, hematology, infectious disease, infertility and ophthalmology. Given the promising studies for a wide range of medical conditions, coupled with a excellent safety profile, the potential for NAC in the treatment of human disease appears considerable. Dr Leonore A Herzenberg from Stanford University, a pioneer of redox physiology and the use of NAC, provides a succinct history of the development of the therapeutic use of NAC for medical disease. This is followed by a series of basic science chapters outlining the role of NAC in important physiological processes, including modulation of dopamine and glutamate neurotransmitter systems, redox and mitochondrial metabolism, apoptosis and inflammation. The last section of the book is dedicated to clinically oriented chapters that comprehensively review the literature on medical disorders in which NAC has been found to be effective, including toxicity and cardiovascular, gastrointestinal, neurological, psychiatric, pulmonary and renal disorders. Each chapter reviews the theoretical biological mechanisms of NAC for the specific diseases reviewed, rates the clinical studies using a standardized criteria in order to provide an objective level of evidence and grade of recommendation for the use of NAC for specific medical conditions and outlines the ongoing clinical trials examining NAC for the treatment of specific diseases. Final chapters review the clinical evidence verifying that specific theoretical biological mechanisms are actually being targeted by NAC in medical disease. Studies on the pharmacology, formulation and potential adverse effects of NAC are also reviewed. A final chapter synthesizes the clinical studies to suggest that the effectiveness of NAC may signal a new basic physiological disorder, glutathione deficiency, which may be an important pathophysiological mechanism of many diseases.

Top Download:

Best Books