antimicrobial resistance and implications for the 21st century emerging infectious diseases of the 21st century

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Antimicrobial Resistance And Implications For The 21st Century

Author : I.W. Fong
ISBN : 9780387724188
Genre : Medical
File Size : 70. 30 MB
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This comprehensive, up-to-date volume defines the issues and offers potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria, viruses including HIV and herpes, parasites and fungi. The chapters explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions.

Antimicrobial Resistance In Developing Countries

Author : Aníbal de J. Sosa
ISBN : 0387893709
Genre : Science
File Size : 74. 23 MB
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Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Antimicrobial Resistance In The 21st Century

Author : I.W. Fong
ISBN : 3319785370
Genre : Medical
File Size : 41. 13 MB
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This comprehensive, up-to-date volume defines the issues and offers potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria, viruses including HIV and herpes, parasites and fungi. The chapters explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions.

Microbial Threats To Health

Author : Institute of Medicine
ISBN : 0309185548
Genre : Medical
File Size : 22. 34 MB
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Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Emerging Respiratory Infections In The 21st Century An Issue Of Infectious Disease Clinics E Book

Author : Alimuddin Zumla
ISBN : 9781455700387
Genre : Medical
File Size : 44. 83 MB
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Respiratory infections are among the most common causes of morbidity and mortality worldwide. These infections present a special challenge to physicians for several reasons, including of the recent disasters caused by severe acute respiratory syndrome (SARS) and bird and swine influenza, the increase in viral and bacterial resistance to currently available anti-microbial drugs, the increased frequency of new viral lung infections in clinical practice, and the worldwide emergence of deadly drug-resistant forms of TB. For these reasons, it is important for infectious disease specialists to have an overview of emerging respiratory infections.

Bacterial Resistance To Antimicrobials

Author : Richard G. Wax
ISBN : 0824744934
Genre : Science
File Size : 74. 16 MB
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Focuses on combating bacterial pathogens by understanding their strategies of defense! Each chapter begins with a summary of concepts, so those not actively working in the field gain an overall picture of what follows! Highlights antibiotic resistance in pathogens that poses the greatest threat to human health! Containing nearly 2000 references for additional research, Bacterial Resistance to Antimicrobials discusses the ecology of drug resistance genes, acquired response, and selection in natural bacterial populations describes global response systems that are a basis of resistance details antibiotic modification, inactivation, and host target modification as means of resistance development considers efflux mechanisms, one of the major causes of multidrug resistance covers concepts for developing therapies against multidrug resistant organisms emphasizes the structural basis of lactamases and other enzymes involved in inactivation of antibiotics surveys the epidemiology of methicillin resistance among nosocomial isolates and community-acquired strains outlines molecular detection methods for mainstream diagnostic tests assesses the promise of modern genomics to identify novel targets for drug discovery screening Presenting the molecular basis, methods of detection and identification, and concepts for reducing the development and spread of resistant bacterial strains, Bacterial Resistance to Antimicrobials is an excellent reference for microbiologists, pharmacists, public health officials, infectious disease specialists, organic and medicinal chemists, and upper-level undergraduate and graduate students in these disciplines.

Genetics And Evolution Of Infectious Diseases

Author : Michel Tibayrenc
ISBN : 9780128001530
Genre : Medical
File Size : 52. 32 MB
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Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field of infectious disease

Global Health In The 21st Century

Author : Debra L. DeLaet
ISBN : 9781317258988
Genre : Education
File Size : 34. 63 MB
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Perhaps no other public policy issue has greater potential to affect some of the most significant economic, political, social, and ethical changes of the 21st century than global health. In this book, a scholar/physician team authors a comprehensive introduction to global health issues and emphasises the potential of public health intervention to improve the longevity and quality of human life across the globe. The authors have lived and worked in Africa as well as in medically underserved areas of the United States, so they write with firsthand experience and authority. Using themes of interconnectedness, globalisation, and united concern from citizens, this book encourages readers to consider the role that they might play as engaged citizens in taking on the global public health challenges of the 21st century including everything from AIDs and flu to tobacco, obesity, and threats in conflict zones.

Emerging Risks In The 21st Century An Agenda For Action

Author : OECD
ISBN : 9264101225
Genre :
File Size : 80. 82 MB
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This book explores the implications of newly developing risks such as hugely damaging hurricanes, new diseases, terrorist attacks, and disruptions to critical infrastructures.

Antibiotic Resistance

Author : Karl S. Drlica
ISBN : 0132117320
Genre : Medical
File Size : 45. 9 MB
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Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.

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