apoptosis

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Apoptosis

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ISBN : 9780080496610
Genre : Science
File Size : 63. 12 MB
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Apoptosis provides a current and comprehensive collection of methods for the study of cell death. Using a diverse range of technical approaches and model systems, the chapters in this volume cover topics from the cellular and organismal to the molecular and anatomical. The methods are illustrated with user-friendly recipes and over 100 tables, halftones, and diagrams. Current methodologies for studying cell death Wide range of model systems Molecular, biochemical, cellular, and genetic approaches Complements the original Cell Death volume Up-to-date methodology for a fast moving field Designed with the needs of both basic scientists and clinicians in mind Authors are leaders in their respective fields

Apoptosis

Author : Christopher Potten
ISBN : 052162679X
Genre : Medical
File Size : 66. 1 MB
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Looks at programmed cell death in the context of the normal life and death cycle of cells and multicelluar organisms and summarizes the latest techniques for the study of cells.

Application Of Apoptosis To Cancer Treatment

Author : Mels Sluyser
ISBN : 1402033036
Genre : Medical
File Size : 79. 77 MB
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Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why the cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients. Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. He brings together a collection of papers written by the world’s leading experts in these fields.

Apoptosis In Health And Disease

Author : Robert R. Ruffolo, Jr.
ISBN : 9780203304624
Genre : Science
File Size : 57. 12 MB
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The impact of Apoptosis, or programmed cell death, is thought to play a crucial role in the development and progression of disease. Whilst Apoptosis remains extensively studied in the context of immunology, the focus of research has greatly expanded to investigate the key role it is now believed to play in hematopoiesis, angiogenesis, inflammation and organ remodelling. It is hoped that, with an increase in our understanding of the mechanisms controlling apoptosis, there will come the development of a new class of drugs which can pharmacologically manipulate apoptosis and thus provide a means to treat important diseases which currently pose problems to our society. Containing papers presented at the Eleventh SmithKline Beecham Pharmaceuticals United States Research Symposium and with contributions from leading researchers, Apoptosis in Health and Disease offers a comprehensive review of important developments and research in the field.

Apoptosis In Neurobiology

Author : Yusuf A. Hannun
ISBN : 142004849X
Genre : Science
File Size : 42. 15 MB
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The rapid growth of the study of apoptosis-mechanism-driven, regulated cell death-has created an urgent need for reliable documentation of the different approaches to and methods of studying the various aspects of the field. Apoptosis in Neurobiology is an important resource for researchers in this emerging frontier of biomedical study. This volume allows the uninitiated neuroscientist intellectual and practical access to the study of apoptosis, with special consideration to the nervous system. The first section concentrates on conceptual approaches to the study of apoptosis in neurobiology and its significance to the nervous system. The second section provides a user-friendly approach to methods and techniques in the study of apoptosis as applied to neurobiology.

Apoptosis

Author : Douglas R. Green
ISBN : 9781139498739
Genre : Science
File Size : 71. 98 MB
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Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.

Apoptosis Methods And Protocols

Author : Hugh J. M. Brady
ISBN : 9781592598120
Genre : Science
File Size : 61. 39 MB
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The ability to detect and quantify apoptosis, to understand its biochemistry, and to identify its regulatory genes and proteins is crucial to biomedical research. In this book, expert laboratorians describe in step-by-step detail the techniques they have perfected to investigate the critical steps involved in the apoptotic process.

Apoptosis And Cancer

Author : Gil Mor
ISBN : 9781588294579
Genre : Medical
File Size : 74. 28 MB
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The aim of Apoptosis and Cancer is to describe the performance of contemporary techniques for studying the biology of apoptosis and its role in cancer. The protocols described will aid both the academic laboratory interested in further characterizing the mechanisms of apoptosis, as well as the industry laboratory, aimed at identifying new target molecules or screening for new compounds with potential clinical use.

Apoptosis

Author : Marc Diederich
ISBN : UVA:X004781092
Genre : Science
File Size : 68. 58 MB
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This volume concerns all aspects of apoptosis from signaling pathways to the therapeutic tools that can be derived from an increasing knowledge about the phenomenon of cell death. Discussed in this volume are cell death and development; Mitochondria as regulators of apoptosis, apoptotic signal transduction pathways inhibitors and activation of apoptosis, receptors as mediators of cell death; apoptosis in human disease, including diabetes, blood diseases, and neurodegenerative and cardiovascular disease, transcriptional and post-transcriptional regulation of apoptosis; chromatin structure and apoptosis; the p53 family; and the cell cycle and cell death. Also discussed are caspases and glutathione.

Systems Biology Of Apoptosis

Author : Inna N. Lavrik
ISBN : 9781461440093
Genre : Science
File Size : 61. 41 MB
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Systems Biology of Apoptosis summarizes all current achievements in this emerging field. Apoptosis is a process common to all multicellular organisms. Apoptosis leads to the elimination of cells via a complex but highly defined cellular programme. Defects in the regulation of apoptosis result in serious diseases such as cancer, autoimmunity, AIDS and neurodegeneration. Recently, a substantial step forward in understanding the complex apoptotic pathways has been made by utilising systems biology approaches. Systems biology combines rigorous mathematical modelling with experimental approaches in a closed loop cycle for advancing our knowledge about complex biological processes. In this book, the editor describes the contemporary systems biology studies devoted to apoptotic signaling and focuses on the question how systems biology helps to understand life/death decisions made in the cell and to develop new approaches to rational treatment strategies.

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