applying big data analytics in bioinformatics and medicine

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Applying Big Data Analytics In Bioinformatics And Medicine

Author : Lytras, Miltiadis D.
ISBN : 9781522526087
Genre : Computers
File Size : 55. 5 MB
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Many aspects of modern life have become personalized, yet healthcare practices have been lagging behind in this trend. It is now becoming more common to use big data analysis to improve current healthcare and medicinal systems, and offer better health services to all citizens. Applying Big Data Analytics in Bioinformatics and Medicine is a comprehensive reference source that overviews the current state of medical treatments and systems and offers emerging solutions for a more personalized approach to the healthcare field. Featuring coverage on relevant topics that include smart data, proteomics, medical data storage, and drug design, this publication is an ideal resource for medical professionals, healthcare practitioners, academicians, and researchers interested in the latest trends and techniques in personalized medicine.

Big Data Analytics In Bioinformatics And Healthcare

Author : Wang, Baoying
ISBN : 9781466666122
Genre : Computers
File Size : 27. 96 MB
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As technology evolves and electronic data becomes more complex, digital medical record management and analysis becomes a challenge. In order to discover patterns and make relevant predictions based on large data sets, researchers and medical professionals must find new methods to analyze and extract relevant health information. Big Data Analytics in Bioinformatics and Healthcare merges the fields of biology, technology, and medicine in order to present a comprehensive study on the emerging information processing applications necessary in the field of electronic medical record management. Complete with interdisciplinary research resources, this publication is an essential reference source for researchers, practitioners, and students interested in the fields of biological computation, database management, and health information technology, with a special focus on the methodologies and tools to manage massive and complex electronic information.

Big Data Analysis For Bioinformatics And Biomedical Discoveries

Author : Shui Qing Ye
ISBN : 9781498724548
Genre : Mathematics
File Size : 58. 74 MB
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Demystifies Biomedical and Biological Big Data Analyses Big Data Analysis for Bioinformatics and Biomedical Discoveries provides a practical guide to the nuts and bolts of Big Data, enabling you to quickly and effectively harness the power of Big Data to make groundbreaking biological discoveries, carry out translational medical research, and implement personalized genomic medicine. Contributing to the NIH Big Data to Knowledge (BD2K) initiative, the book enhances your computational and quantitative skills so that you can exploit the Big Data being generated in the current omics era. The book explores many significant topics of Big Data analyses in an easily understandable format. It describes popular tools and software for Big Data analyses and explains next-generation DNA sequencing data analyses. It also discusses comprehensive Big Data analyses of several major areas, including the integration of omics data, pharmacogenomics, electronic health record data, and drug discovery. Accessible to biologists, biomedical scientists, bioinformaticians, and computer data analysts, the book keeps complex mathematical deductions and jargon to a minimum. Each chapter includes a theoretical introduction, example applications, data analysis principles, step-by-step tutorials, and authoritative references.

Big Data Analytics In Genomics

Author : Ka-Chun Wong
ISBN : 9783319412795
Genre : Computers
File Size : 47. 91 MB
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This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed in the book are intended to tackle crucial biological questions using big data, and are appropriate for either newcomers or veterans in the field.This volume offers thirteen peer-reviewed contributions, written by international leading experts from different regions, representing Argentina, Brazil, China, France, Germany, Hong Kong, India, Japan, Spain, and the USA. In particular, the book surveys three main areas: statistical analytics, computational analytics, and cancer genome analytics. Sample topics covered include: statistical methods for integrative analysis of genomic data, computation methods for protein function prediction, and perspectives on machine learning techniques in big data mining of cancer. Self-contained and suitable for graduate students, this book is also designed for bioinformaticians, computational biologists, and researchers in communities ranging from genomics, big data, molecular genetics, data mining, biostatistics, biomedical science, cancer research, medical research, and biology to machine learning and computer science. Readers will find this volume to be an essential read for appreciating the role of big data in genomics, making this an invaluable resource for stimulating further research on the topic.

Strategies In Biomedical Data Science

Author : Jay A. Etchings
ISBN : 9781119256182
Genre : Medical
File Size : 22. 18 MB
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An essential guide to healthcare data problems, sources, and solutions Strategies in Biomedical Data Science provides medical professionals with much-needed guidance toward managing the increasing deluge of healthcare data. Beginning with a look at our current top-down methodologies, this book demonstrates the ways in which both technological development and more effective use of current resources can better serve both patient and payer. The discussion explores the aggregation of disparate data sources, current analytics and toolsets, the growing necessity of smart bioinformatics, and more as data science and biomedical science grow increasingly intertwined. You'll dig into the unknown challenges that come along with every advance, and explore the ways in which healthcare data management and technology will inform medicine, politics, and research in the not-so-distant future. Real-world use cases and clear examples are featured throughout, and coverage of data sources, problems, and potential mitigations provides necessary insight for forward-looking healthcare professionals. Big Data has been a topic of discussion for some time, with much attention focused on problems and management issues surrounding truly staggering amounts of data. This book offers a lifeline through the tsunami of healthcare data, to help the medical community turn their data management problem into a solution. Consider the data challenges personalized medicine entails Explore the available advanced analytic resources and tools Learn how bioinformatics as a service is quickly becoming reality Examine the future of IOT and the deluge of personal device data The sheer amount of healthcare data being generated will only increase as both biomedical research and clinical practice trend toward individualized, patient-specific care. Strategies in Biomedical Data Science provides expert insight into the kind of robust data management that is becoming increasingly critical as healthcare evolves.

Application Of Big Data For National Security

Author : Babak Akhgar
ISBN : 9780128019733
Genre : Political Science
File Size : 75. 26 MB
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Application of Big Data for National Security provides users with state-of-the-art concepts, methods, and technologies for Big Data analytics in the fight against terrorism and crime, including a wide range of case studies and application scenarios. This book combines expertise from an international team of experts in law enforcement, national security, and law, as well as computer sciences, criminology, linguistics, and psychology, creating a unique cross-disciplinary collection of knowledge and insights into this increasingly global issue. The strategic frameworks and critical factors presented in Application of Big Data for National Security consider technical, legal, ethical, and societal impacts, but also practical considerations of Big Data system design and deployment, illustrating how data and security concerns intersect. In identifying current and future technical and operational challenges it supports law enforcement and government agencies in their operational, tactical and strategic decisions when employing Big Data for national security Contextualizes the Big Data concept and how it relates to national security and crime detection and prevention Presents strategic approaches for the design, adoption, and deployment of Big Data technologies in preventing terrorism and reducing crime Includes a series of case studies and scenarios to demonstrate the application of Big Data in a national security context Indicates future directions for Big Data as an enabler of advanced crime prevention and detection

Big Data In Omics And Imaging

Author : Momiao Xiong
ISBN : 9781498725804
Genre : Mathematics
File Size : 46. 28 MB
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Big Data in Omics and Imaging: Association Analysis addresses the recent development of association analysis and machine learning for both population and family genomic data in sequencing era. It is unique in that it presents both hypothesis testing and a data mining approach to holistically dissecting the genetic structure of complex traits and to designing efficient strategies for precision medicine. The general frameworks for association analysis and machine learning, developed in the text, can be applied to genomic, epigenomic and imaging data. FEATURES ??Bridges the gap between the traditional statistical methods and computational tools for small genetic and epigenetic data analysis and the modern advanced statistical methods for big data ??Provides tools for high dimensional data reduction ??Discusses searching algorithms for model and variable selection including randomization algorithms, Proximal methods and matrix subset selection ??Provides real-world examples and case studies ??Will have an accompanying website with R code The book is designed for graduate students and researchers in genomics, bioinformatics, and data science. It represents the paradigm shift of genetic studies of complex diseases– from shallow to deep genomic analysis, from low-dimensional to high dimensional, multivariate to functional data analysis with next-generation sequencing (NGS) data, and from homogeneous populations to heterogeneous population and pedigree data analysis. Topics covered are: advanced matrix theory, convex optimization algorithms, generalized low rank models, functional data analysis techniques, deep learning principle and machine learning methods for modern association, interaction, pathway and network analysis of rare and common variants, biomarker identification, disease risk and drug response prediction. ?

Signal Processing And Machine Learning For Biomedical Big Data

Author : Ervin Sejdic
ISBN : 9781351061216
Genre : Medical
File Size : 45. 17 MB
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This will be a comprehensive, multi-contributed reference work that will detail the latest research and developments in biomedical signal processing related to big data medical analysis. It will describe signal processing, machine learning, and parallel computing strategies to revolutionize the world of medical analytics and diagnosis as presented by world class researchers and experts in this important field. The chapters will desribe tools that can be used by biomedical and clinical practitioners as well as industry professionals. It will give signal processing researchers a glimpse into the issues faced with Big Medical Data.

Data Mining For Bioinformatics

Author : Sumeet Dua
ISBN : 9780849328015
Genre : Computers
File Size : 24. 65 MB
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Covering theory, algorithms, and methodologies, as well as data mining technologies, Data Mining for Bioinformatics provides a comprehensive discussion of data-intensive computations used in data mining with applications in bioinformatics. It supplies a broad, yet in-depth, overview of the application domains of data mining for bioinformatics to help readers from both biology and computer science backgrounds gain an enhanced understanding of this cross-disciplinary field. The book offers authoritative coverage of data mining techniques, technologies, and frameworks used for storing, analyzing, and extracting knowledge from large databases in the bioinformatics domains, including genomics and proteomics. It begins by describing the evolution of bioinformatics and highlighting the challenges that can be addressed using data mining techniques. Introducing the various data mining techniques that can be employed in biological databases, the text is organized into four sections: Supplies a complete overview of the evolution of the field and its intersection with computational learning Describes the role of data mining in analyzing large biological databases—explaining the breath of the various feature selection and feature extraction techniques that data mining has to offer Focuses on concepts of unsupervised learning using clustering techniques and its application to large biological data Covers supervised learning using classification techniques most commonly used in bioinformatics—addressing the need for validation and benchmarking of inferences derived using either clustering or classification The book describes the various biological databases prominently referred to in bioinformatics and includes a detailed list of the applications of advanced clustering algorithms used in bioinformatics. Highlighting the challenges encountered during the application of classification on biological databases, it considers systems of both single and ensemble classifiers and shares effort-saving tips for model selection and performance estimation strategies.

Progress And Challenges In Precision Medicine

Author : Mukesh Verma
ISBN : 9780128095027
Genre : Medical
File Size : 55. 52 MB
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Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

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