bioconjugate techniques third edition

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Bioconjugate Techniques

Author : Greg T. Hermanson
ISBN : 9780123822406
Genre : Science
File Size : 47. 41 MB
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Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

Organische Chemie

Author : Jonathan Clayden
ISBN : 3642347150
Genre : Science
File Size : 87. 80 MB
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Ein neuer Stern am Lehrbuch-Himmel: Organische Chemie von Clayden, Greeves, Warren - der ideale Begleiter für alle Chemiestudenten. Der Schwerpunkt dieses didaktisch durchdachten, umfassenden vierfarbigen Lehrbuches liegt auf dem Verständnis von Mechanismen, Strukturen und Prozessen, nicht auf dem Lernen von Fakten. Organische Chemie entpuppt sich als dabei als ein kohärentes Ganzes, mit zahlreichen logischen Verbindungen und Konsequenzen sowie einer grundlegenden Struktur und Sprache. Dank der Betonung von Reaktionsmechanismen, Orbitalen und Stereochemie gewinnen die Studierenden ein solides Verständnis der wichtigsten Faktoren, die für alle organisch-chemischen Reaktionen gelten. So lernen sie, auch Reaktionen, die ihnen bisher unbekannt waren, zu interpretieren und ihren Ablauf vorherzusagen. Der direkte, persönliche, studentenfreundliche Schreibstil motiviert die Leser, mehr erfahren zu wollen. Umfangreiche Online-Materialien führen das Lernen über das gedruckte Buch hinaus und vertiefen das Verständnis noch weiter.

Soft Matter Self Assembly

Author : C.N. Likos
ISBN : 9781614996620
Genre : Science
File Size : 69. 5 MB
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Self-assembly is one of the key concepts in contemporary soft condensed matter. It is an umbrella term which encompasses the various modes of spontaneous organization of micrometer-and submicrometer-sized particles into ordered structures of various degrees of complexity, yet it often relies on remarkably simple interactions and mechanisms. Self-assembly is one of the key principles used by nature to construct living matter, where it frequently takes place in a hierarchical fashion. This book contains the lectures from the Enrico Fermi summer school: Soft Matter Self-assembly, held in Varenna, Italy, in June and July 2015. The primary aim of the school was to cover the most exciting modern aspects of self-assembly in soft condensed matter physics, and to enable Ph.D. students and postdocs to engage with some of the most exciting and current topics in the physics of colloids through a series of mini-courses and seminars hosted by leading figures in the field. Subjects covered include: colloids with directional bonding; pathways of self-organization; self-assembly hydrodynamics; polymer structure and dynamics; liquid-crystal colloid dispersions; and self-organizing nanosystems. The proceedings also include two reprints from Reviews of Modern Physics, and will be of interest to both students and experts in the field.

Dna Nanotechnology For Bioanalysis From Hybrid Dna Nanostructures To Functional Devices

Author : Arrabito Giuseppe Domenico
ISBN : 9781786343819
Genre : Technology & Engineering
File Size : 20. 77 MB
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This book is intended for non-specialists and students, presenting a unique introduction to the field of DNA nanotechnology. The primary focus is on the extraordinary advantages of specificity and sensitivity obtained by integrating DNA nanostructures in bioanalytical devices. DNA Nanotechnology for Bioanalysis provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized software-aided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Also provided is a concise review on non-canonical DNA structures (such as G-quadruplexes) and their targeting by small molecules for applications in pharmacology. Finally, it describes the exciting applications of DNA nanostructures in life sciences and nanomedicine, including ultraspecific molecular delivery, control of cell behavior, analysis of cell lysate and DNA-based nano-tools for super-resolution sub-cellular imaging. Contents: Nanotechnology and the Unique Role of DNA (Elisa-C Schöneweiβ, Andreas Jaekel and Barbara Saccà)DNA as Building Material at the Nanoscale: From Concepts to Software-aided Design (Wolfgang Pfeifer, Georg Homa, Giuseppe Arrabito and Barbara Saccà)DNA Sensors for the Detection of Biomolecules and Biochemical Conditions (Birgitta R Knudsen, Anni H Andersen, Magnus Stougaard, Giuseppe Arrabito, Raffaella Suriano and Yi-Ping Ho)DNA Nanostructures in Cell Biology and Medicine (Liqian Wang and Giuseppe Arrabito)Targeting G-quadruplex DNA as Potential Anti-cancer Therapy (Riccardo Bonsignore, Elisa Trippodo and Giampaolo Barone)DNA-aided Super-resolution Bioimaging (JiaJun Li, Giuseppe Arrabito and ZhaoShuai Gao) Readership: Non-specialists, undergraduate students and researchers who are interested in learning the basics of DNA nanotechnology. Keywords: DNA Nanotechnology;Nanostructures;Non-Canonical DNA Structures;G Quadruplexes;Nano-Tools;DNA Origami;DNA Aptamers;Biosensors;Drug DeliveryReview: Key Features: Constitutes a clear introduction to the field of DNA NanotechnologyWritten in an easy and catchy styleContains information of the most recent findings in the world of DNA Nanotechnology (up to 2016), optimal for researchers who want to keep updated with the latest breakthroughs in the field

Statistik Ii F R Dummies

Author : Deborah J. Rumsey
ISBN : 9783527669240
Genre : Mathematics
File Size : 45. 70 MB
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Vom Absolutrang bis zum Zweifach-Varianzanalysemodell – alles, was Sie über weiterführende Statistik wissen sollten Es gibt Qualen, große Qualen und Statistik, so sehen es viele Studenten. Mit diesem Buch lernen Sie weiterführende Statistik so leicht wie möglich. Deborah Rumsey zeigt Ihnen, wie Sie Varianzanalysen und Chi-Quadrat-Tests berechnen, wie Sie mit Regressionen arbeiten, ein Modell erstellen, Korrelationen bilden, nichtparametrische Prozeduren durchführen und vieles mehr. Aber auch die Grundlagen der Statistik bleiben nicht außen vor und deshalb erklärt Ihnen die Autorin, was Sie zu Mittelwerten, Vertrauensintervallen und Co wissen sollten. So lernen Sie die Methoden, die Sie brauchen, und erhalten das Handwerkszeug, um erfolgreich Ihre Statistikprüfungen zu bestehen. Sie erfahren: • Wie Sie mit multiplen Regressionen umgehen • Was es mit dem Vorzeichentest und dem Vorzeichenrangtest auf sich hat • Wie Sie sich innerhalb der statistischen Techniken zurechtfinden • Was das richtige Regressionsmodell für Ihre Analyse ist • Wie Regression und ANOVA zusammenhängen

Silicon Nanomaterials Sourcebook

Author : Klaus D. Sattler
ISBN : 9781351649599
Genre : Science
File Size : 78. 28 MB
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This comprehensive tutorial guide to silicon nanomaterials spans from fundamental properties, growth mechanisms, and processing of nanosilicon to electronic device, energy conversion and storage, biomedical, and environmental applications. It also presents core knowledge with basic mathematical equations, tables, and graphs in order to provide the reader with the tools necessary to understand the latest technology developments. From low-dimensional structures, quantum dots, and nanowires to hybrid materials, arrays, networks, and biomedical applications, this Sourcebook is a complete resource for anyone working with this materials: Covers fundamental concepts, properties, methods, and practical applications. Focuses on one important type of silicon nanomaterial in every chapter. Discusses formation, properties, and applications for each material. Written in a tutorial style with basic equations and fundamentals included in an extended introduction. Highlights materials that show exceptional properties as well as strong prospects for future applications. Klaus D. Sattler is professor physics at the University of Hawaii, Honolulu, having earned his PhD at the Swiss Federal Institute of Technology (ETH) in Zurich. He was honored with the Walter Schottky Prize from the German Physical Society, and is the editor of the sister work also published by Taylor & Francis, Carbon Nanomaterials Sourcebook, as well as the acclaimed multi-volume Handbook of Nanophysics.

Advances In Bioorganometallic Chemistry

Author : Toshikazu Hirao
ISBN : 9780128141984
Genre : Science
File Size : 40. 26 MB
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Advances in Bioorganometallic Chemistry examines the synthesis, structure and reactivity of bioorganometallics, their pharmaceutical applications, hydrogenase, vitamin B12-like systems, and metalloproteins. It is written by the top researchers in the field and compiled by editors Toshikazu Hirao and Toshiyuki Moriuchi. Developments in this new field of bioorganometallic chemistry, a hybrid between biology and organometallic chemistry, happen very quickly and this comprehensive reference offers the latest research and findings in the field. The book features a discussion of the synthesis, structure, and reactivity of bioorganometallics, and an examination of hydrogenase-like systems, which were designed to demonstrate catalytic activities and functional properties. Advances in Bioorganometallic Chemistry also includes a discussion of bioorganometallics as they relate to medicinal chemistry, specifically applications of metalloproteins, metalloenzymes, and applications in bioimaging. The book concludes with coverage of vitamin B12-like systems, including the latest developments in derivatives designed to perform bio-inspired catalytic reactions. This work is a valuable resource for chemists working in organometallic chemistry and biology, including biochemists, bioorganic chemists, bioinorganic chemists, as well as pharmaceutical scientists, medicinal chemists, and students studying in these areas. Representative authors: R. H. Fish, T. Moriuchi, T. Hirao, H.-B. Kraatz, H. Takaya, T. P. Curran, G. van Koten. E. Rosenberg, J. M. Lynam, C. G. Hartinger, U. Schatzschneider, G. S. Smith, R. Alberto, S. Takenaka, T. Ihara, T. Hayashi, T. Ueno, P. Schollhammer, Y. Shomura, Y. Hisaeda, H. Shimakoshi, B. Kräutler Provides a balanced overview of the latest research in the field of bioorganometallic chemistry, drawing together the top researchers from around the world Covers topics in the areas of synthesis, reactivity, hydrogenase-like systems, medicinal chemistry, applications of metalloproteins, metalloenzymes, and applications in bioimaging

Theorie Der Supraleitung

Author : Max v. Laue
ISBN : 9783642884726
Genre : Science
File Size : 42. 82 MB
Format : PDF
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In Situ Hybridisierung

Author : Andrew R. Leitch
ISBN : 3860252259
Genre :
File Size : 67. 78 MB
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Lehren Aus Weimar Die Weimarer Reichsverfassung Im Vergleich Zum Grundgesetz Der Bundesrepublik Deutschland In Seiner Fassung Vom 23 5 1949

Author : Felix Silvester
ISBN : 9783656323990
Genre : Political Science
File Size : 23. 93 MB
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Studienarbeit aus dem Jahr 2012 im Fachbereich Politik - Politische Systeme - Politisches System Deutschlands, Note: 2,0, Friedrich-Alexander-Universität Erlangen-Nürnberg (Institut für Politische Wissenschaft I), Veranstaltung: Das Parteiensystem der Bundesrepublik Deutschland, Sprache: Deutsch, Abstract: Seit Jahrzehnten wird sowohl unter Historikern als auch unter Politikwissenschaftlern die Gewichtigkeit der „Konstruktionsfehler“ der Verfassung in Weimar und deren Folgen für die Weltgeschichte immer wieder diskutiert. Während einige Forscher die Ansicht vertreten, die Weimarer Verfassung selbst habe staatsfeindlichen Kräften und somit letzten Endes den Nationalsozialisten Tür und Tor geöffnet, wird in der nachfolgenden deutschen Verfassung, dem Grundgesetz der Bunderepublik Deutschland ein Lernen aus Weimar gesehen. Doch ist dies wirklich der Fall? Haben die Schaffer des Grundgesetzes wirklich ihre Lehren aus der Geschichte gezogen, und die Fehler ihrer Kollegen aus Weimarer Tagen nicht wiederholt? ...

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