biological inorganic chemistry an introduction

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Biological Inorganic Chemistry

Author : Robert R. Crichton
ISBN : 9780444537829
Genre : Science
File Size : 56. 56 MB
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The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. This revised and expanded text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten, chromium and selected non-metals. The final five chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Biological Inorganic Chemistry

Author : Robert R. Crichton
ISBN : 9780444527400
Genre : Science
File Size : 46. 94 MB
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Contents include: 'An Overview of Metals in Biology', 'Structural and Molecular Biology for Chemists', 'Metal Assimilation Pathways', 'Biomineralisation' and 'Metals in Medicine and the Environment'.

Practical Approaches To Biological Inorganic Chemistry

Author : Robert R. Crichton
ISBN : 9780444563590
Genre : Science
File Size : 30. 78 MB
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The book reviews the use of spectroscopic and related methods to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique including relevant theory, clearly explains what it is and how it works and then presents how the technique is actually used to evaluate biological structures. Practical examples and problems are included to illustrate each technique and to aid understanding. Designed for students and researchers who want to learn both the basics, and more advanced aspects of bioinorganic chemistry. Many colour illustrations enable easier visualization of molecular mechanisms and structures Worked examples and problems are included to illustrate and test the reader’s understanding of each technique Written by a multi-author team who use and teach the most important techniques used today to analyse complex biological structures

Inorganic Biochemistry

Author : J. A. Cowan
ISBN : 0471188956
Genre : Science
File Size : 48. 91 MB
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Developments in the expanding field of inorganic biochemistry have led to major additions to this teaching text. The author illustrates the use of basic principles to tackle important problems in the field of inorganic biochemistry.

Biological Inorganic Chemistry Structure And Reactivity

Author : CTI Reviews
ISBN : 9781490297552
Genre : Education
File Size : 44. 51 MB
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Facts101 is your complete guide to Biological Inorganic Chemistry, Structure and Reactivity. In this book, you will learn topics such as as those in your book plus much more. With key features such as key terms, people and places, Facts101 gives you all the information you need to prepare for your next exam. Our practice tests are specific to the textbook and we have designed tools to make the most of your limited study time.

An Introduction To Bio Inorganic Chemistry

Author : David Raymond Williams
ISBN : UCAL:B4493319
Genre : Science
File Size : 79. 9 MB
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Biological Inorganic Chemistry

Author : Ivano Bertini
ISBN : 1891389432
Genre : Science
File Size : 45. 68 MB
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The long awaited text for 21st century courses in biological inorganic chemistry is now available. Organized and edited by Ivano Bertini, Harry Gray, Ed Stiefel, and Joan Valentine, with contributions from many other world leaders in the field, this all-new book is equally appropriate for graduate or senior undergraduate courses in bioinorganic chemistry. The book has been extensively class-tested at Princeton and UCLA, and it includes tutorials in biology and biochemistry and in inorganic chemistry to aid students of varying backgrounds. The main text is divided into two parts. Part A, 'Overviews of Biological Inorganic Chemistry', sets forth the unifying principles of the field. A full course in bioinorganic chemistry could be based entirely on this overview section, which is a really a book within a book! Part B, 'Metal-Ion Containing Biological Systems', describes specific classes of systems in detail. A special feature is the strong connection to the genomic revolution that has dramatically enhanced our ability to define the function of gene products in living organisms. Throughout the book, protein data bank codes are given for structures discussed in the text, and students are encouraged to learn to use the PDB in their courses and research.

Computational Inorganic And Bioinorganic Chemistry

Author : Edward I. Solomon
ISBN : 9781118617243
Genre : Science
File Size : 88. 34 MB
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Over the past several decades there have been major advances in our ability to computationally evaluate the electronic structure of inorganic molecules, particularly transition metal systems. This advancement is due to the Moore’s Law increase in computing power as well as the impact of density functional theory (DFT) and its implementation in commercial and freeware programs for quantum chemical calculations. Improved pure and hybrid density functionals are allowing DFT calculations with accuracy comparable to high-level Hartree-Fock treatments, and the results of these calculations can now be evaluated by experiment. When calculations are correlated to, and supported by, experimental data they can provide fundamental insight into electronic structure and its contributions to physical properties and chemical reactivity. This interplay continues to expand and contributes to both improved value of experimental results and improved accuracy of computational predictions. The purpose of this EIC Book is to provide state-of-the-art presentations of quantum mechanical and related methods and their applications, written by many of the leaders in the field. Part 1 of this volume focuses on methods, their background and implementation, and their use in describing bonding properties, energies, transition states and spectroscopic features. Part 2 focuses on applications in bioinorganic chemistry and Part 3 discusses inorganic chemistry, where electronic structure calculations have already had a major impact. This addition to the EIC Book series is of significant value to both experimentalists and theoreticians, and we anticipate that it will stimulate both further development of the methodology and its applications in the many interdisciplinary fields that comprise modern inorganic and bioinorganic chemistry. This volume is also available as part of Encyclopedia of Inorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007 to 2010, representing areas of key developments in the field of inorganic chemistry published in the Encyclopedia of Inorganic Chemistry. Find out more.

Medicinal Inorganic Chemistry

Author : Jonathan L. Sessler
ISBN : UOM:39015062459931
Genre : Science
File Size : 25. 61 MB
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This book, a compilation by experts in the field, is designed to provide an introduction to the area of medicinal inorganic chemistry and to summarize current, state-of-the-art developments in the field. Medicinal inorganic chemistry represents a key thrust area in medicine and biological inorganic chemistry. It is one of great current excitement and achievement. The field of metals in medicine represents an approximate $3 billion dollar a year industry, with successes in the area of Tc- and Gd-based imaging agents and Pt-based cancer therapeutics being major contributors to this bottom line. It has become increasingly apparent, however, that metal-based pharmaceuticals can play a prominent role in areas outside of imaging and oncology, including in those associated with the diagnosis and treatment of metabolism- and genetic disorders, cardiovascular disease, gene therapy, inflammation, reperfusion injury, stroke, diabetes, ALS, malaria, and neurological disease to name but a few. A objective of this book, therefore, is to highlight these opportunities for future advances and to foster further interactions between those working in the metal-based drug development, including imaging agents, and those engaged in the more classic pharmaceutical industries.

Metal Ions In Biological Systems

Author : Astrid Sigel
ISBN : 0203913701
Genre : Science
File Size : 53. 71 MB
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Metal ions are currently used for such applications as diabetes, anti-inflammatory, rheumatoid arthritis, psychiatric, and anti-ulcer medications, using compounds of vanadium, copper and zinc, gold, lithium, and bismuth, respectively. This text explores these applications in addition to an assessment of chelation therapy, uses in environmental sciences, and the human health effects of metal ion deficiency for several elements-magnesium, calcium, zinc, and iron. Featuring contributions from 29 internationally recognized experts, this book offers a timely, authoritative look at ionic complexes in medicine.

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