cancer as a metabolic disease on the origin management and prevention of cancer

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Cancer As A Metabolic Disease

Author : Thomas Seyfried
ISBN : 9781118310304
Genre : Science
File Size : 24. 11 MB
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The book addresses controversies related to the origins of cancerand provides solutions to cancer management and prevention. Itexpands upon Otto Warburg's well-known theory that all cancer is adisease of energy metabolism. However, Warburg did not linkhis theory to the "hallmarks of cancer" and thus his theory wasdiscredited. This book aims to provide evidence, throughcase studies, that cancer is primarily a metabolic diseaserequring metabolic solutions for its management andprevention. Support for this position is derived fromcritical assessment of current cancer theories. Brain cancercase studies are presented as a proof of principle for metabolicsolutions to disease management, but similarities are drawn toother types of cancer, including breast and colon, due tothe same cellular mutations that they demonstrate.

Homeostatic Control Of Brain Function

Author : Detlev Boison
ISBN : 9780199322312
Genre : Medical
File Size : 45. 20 MB
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Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Ketogenic Diet And Metabolic Therapies

Author : Susan A Masino
ISBN : 9780190498016
Genre : Medical
File Size : 79. 87 MB
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Ketogenic diets have been used to successfully treat epilepsy and stop seizures for nearly a century. When more traditional therapies, such as pharmacology, reach their limitations for treatment, the metabolic approach surpasses, targeting the overall physiology and homeostatic functions of the patient. Ketogenic Diet and Metabolic Therapies is the first comprehensive scientific resource on the ketogenic diet, covering the latest research including the biomedical mechanisms, established and emerging applications, metabolic alternatives, and implications for health and disease. Experts in clinical and basic research share their research into mechanisms spanning from ion channels to epigenetics, their insights based on decades of experience with the ketogenic diet in epilepsy, and their evidence for emerging applications ranging from autism to Alzheimer's disease to brain cancer. Research in metabolic therapies has spread into laboratories and clinics of every discipline, and is yielding to entirely new classes of drugs and treatment regimens. The book's editor, Susan A. Masino, brings her unique expertise in clinical and research neurology to the overall scope of this work. To further enhance the scope and quality of this one of a kind book, section editors Eric Kossoff, Jong Rho, Detlev Boison, and Dominic P. D'Agostino lend their oversight on their respective sections.

The Ketogenic Diet

Author : Kristen Mancinelli
ISBN : 9781612434216
Genre : Health & Fitness
File Size : 47. 16 MB
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Prostate Cancer As A Metabolic Disease

Author : Algeciras Algeciras Press
ISBN : 1536970107
Genre :
File Size : 48. 20 MB
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Emerging evidence indicates that altered cellular metabolism is the defining characteristic of nearly all diseases regardless of cellular or tissue origin. In contrast to normal cells, most diseased cells become heavily dependent on alternative metabolic pathways to meet cellular functions. A view of prostate cancer as primarily a metabolic disease will impact approaches to prostate cancer management and prevention. Proceeds from the sale of this book go to the support of an elderly disabled person.

The Cancer Solution

Author : Jack C. Westman, M.D., M.S.
ISBN : 9781480813083
Genre : Health & Fitness
File Size : 30. 52 MB
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"The Cancer Solution: Taking Charge of your Life with Cancer by Jack C. Westman, M.D., shows how much of the failure of the War on Cancer?and more importantly, much of the potential for finally winning it?has to do with the definition of cancer. This book is a wake-up call and a call to action for cancer patients, their loved ones and the general public. Conventional cancer care needs to be vastly improved according to the American Society of Clinical Oncology and the National Cancer Institute. Patients know it firsthand. They are obliged to accept chances for 5-year survival with likely debilitation rather than complete remissions (cures). Everyone is paying the price of excessive cancer care costs in their health care insurance."--Publisher description.

Effortless Healing

Author : Dr. Joseph Mercola
ISBN : 9780553417982
Genre : Health & Fitness
File Size : 49. 31 MB
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Let your body do the work... Do you have to tell your leg to heal from a scrape? Your lungs to take in air? Your body that it’s hungry? No. Your body does these things automatically, effortlessly. Vibrant health is your birthright and within your grasp; you just have to step out of the way. In Effortless Healing, online health pioneer, natural medicine advocate, and bestselling author Dr. Joseph Mercola reveals the nine simple secrets to a healthier, thinner you. The results are amazing and the steps can be as easy to implement as: • Throwing ice cubes in your water to make it more “structured” • Skipping breakfast, as it could be making you fat • Eating up to 75 percent of your calories each day in fat for optimal health, reduction of heart disease, and cancer prevention • Avoiding certain meat and fish, but enjoying butter • Eating sauerkraut (and other fermented foods) to improve your immune system and your mood • Walking barefoot outside to decrease system-wide inflammation (and because it just feels great) • Enjoying a laugh: it’s as good for your blood vessels as fifteen minutes of exercise Effortless Healing is the distillation of decades of Dr. Mercola’s experience and cutting-edge medical knowledge. With his wisdom and that of your body, you can optimize your health, your weight, and your life…effortlessly.

Cancer As A Metabolic Disease

Author : Applied Research Press
ISBN : 1515293386
Genre :
File Size : 58. 83 MB
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Emerging evidence indicates that impaired cellular energy metabolism is the defining characteristic of nearly all cancers regardless of cellular or tissue origin. In contrast to normal cells, which derive most of their usable energy from oxidative phosphorylation, most cancer cells become heavily dependent on substrate level phosphorylation to meet energy demands. Evidence is reviewed supporting a general hypothesis that genomic instability and essentially all hallmarks of cancer, including aerobic glycolysis (Warburg effect), can be linked to impaired mitochondrial function and energy metabolism. A view of cancer as primarily a metabolic disease will impact approaches to cancer management and prevention.

Cancer Management In Small Animal Practice E Book

Author : Carolyn J. Henry
ISBN : 9781437701982
Genre : Medical
File Size : 20. 38 MB
Format : PDF
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Cancer Management in Small Animal Practice provides you with all the tools needed to diagnose, stage, and manage the many different disease entities known as "cancer." This manual is designed to provide you with easy-to-access, clinically relevant details for complete care of the small animal cancer patient, while considering the needs, concerns, and capabilities of the client. It provides quick reference sections for information not included in current oncology texts, including drug interactions and resources for participation in clinical trials. All information is well referenced and the reference section on the accompanying website includes links to the original and related articles. The latest information including diagnostic procedures, treatment modalities, and outcome predictions to help clients make the best decisions for their pets. Expert contributors, renowned for clinical, as well as academic and research expertise, offer a wide breadth and depth of expertise. Full-color format provides accurate visual depictions of specific diseases and procedures to enhance your diagnostic capabilities. Key Points highlight critical information, enabling quick, easy access. Systems approach to diagnosis and management offers logical, systematic, head-to-tail procedure for accurate diagnosis, treatment, and prognosis. Extensive discussions of supportive care limit adverse events and increase patient survival and puts emergency information at the practitioner’s fingertips. Suggested readings highlight the latest information for further investigation and research. Comprehensive drug safety guidelines thoroughly discuss all information required to safely handle and administer cancer drugs. Helpful drug formularies offer available formulations, recommended dosages, toxicities, and relative costs. Chapter on how to access clinical trials provides helpful information and hope for patients and their caregivers.

Hormones And Cancer Breast And Prostate An Issue Of Endocrinology And Metabolism Clinics Of North America E Book

Author : Alice C. Levine
ISBN : 9781455712397
Genre : Medical
File Size : 20. 23 MB
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This issue of Endocrinology Clinics brings the reader up to date on the latest information about hormones and cancer of the breast and prostate. The first section focuses on the breast, and topics covered include the following. The role of sex steroids and their receptors in normal breast development; estrogen carcinogenesis in breast cancer; hormonal mechanisms underlying the relationship between obesity and breast cancer; postmenopausal hormone replacement therapy and the risk of breast cancer; aromatase inhibitors, anti-estrogen and SERMS in the treatment of breast cancer; and androgens in breast cancer in men and women. The second section is devoted to the prostate, and topics covered include the following. Overview of prostate anatomy, histology, and pathology; the critical role of sex steroids in normal prostate development; estrogens and androgens in prostate cancer development and the rationale for hormonal chemopreventive therapies; weighing the clinical evidence regarding the timing and extent of androgen ablative therapy for prostate cancer treatment; new hormonal therapies for castration-resistant prostate cancer; and the management of the side effects of castration therapy.

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