carbon monoxide toxicity

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Carbon Monoxide Poisoning

Author : David G. Penney
ISBN : 9780849384189
Genre : Medical
File Size : 88. 21 MB
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While an ever-present and familiar toxin, carbon monoxide (CO) remains the number one poison in our environment. This silent killer is responsible for over 2,000 deaths a year in the United States alone. The public and healthcare communities need quality information about the many risks presented by carbon monoxide exposure. Edited by a leading expert in the field, Carbon Monoxide Poisoning delineates the successful means to prevent, identify, and manage the effects of CO poisoning. This volume explores new information on CO toxicity, including rehabilitation, the dissemination of information to the public, litigation involving CO poisoning, economic loss assessment, and firefighting. A series of chapters detail the risk of CO poisoning from kitchen ranges, recreational vehicles, and power boats. Expert contributors survey diagnostic procedures and devices, incorporating advances in brain SPECT imaging and non-invasive pulse-oximetry. The book includes chapters that specifically address the pros and cons of hyperbaric oxygen therapy and thoroughly review the physiological effects of acute and long term exposure to CO, as well as the neurocognitive and neurobehavioral sequelae. Whether you are a healthcare professional who treats CO poisoning, a lawyer involved in litigation for loss of life or property due to CO poisoning, or an engineer developing a well-insulated structure with sufficient ventilation; you will face the challenges raised by CO toxicology. Offering the only comprehensive reference on the subject, this multi-faceted guide takes an innovative look at how we can identify, treat, and prevent harmful exposure to carbon monoxide.

Carbon Monoxide Toxicity

Author : David G. Penney
ISBN : 9781420039320
Genre : Science
File Size : 70. 92 MB
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Public interest in the health impacts of carbon monoxide (CO) has been increasing rapidly during the past decade. And rightly so: it is the most ubiquitous environmental poison. Car exhaust fumes, furnaces, gas-powered engines, home water heaters, smoke from all types of fire, and tobacco smoke all contribute to carbon monoxide intoxication - the leading cause of poisoning death in the United States. Even when it doesn't cause death, it often produces lasting, deleterious effects on the central nervous system. From one of the world's top CO experts, Carbon Monoxide Toxicity examines the latest basic science and clinical research from around the world. It addresses the gamut of health-related CO issues, from the history of CO studies to the hidden threat of chronic low-level exposure. The broad themes center on clinical management of various forms of CO poisoning and education of the public on the constant dangers of CO. Thanks to the success of CO environmental health regulations in the U.S., society is much more aware of the threat of CO poisoning. Increasing numbers of people use CO detectors in public buildings, homes, pleasure boats, and aircraft. Carbon Monoxide Toxicity meets the need for current research on the clinical management of CO poisoning. Visit the author's Web site at

Visual Masking And Carbon Monoxide Toxicity

Author : Saul Martin Luria
ISBN : OCLC:4377358
Genre : Carbon monoxide
File Size : 35. 51 MB
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Carbon Monoxide

Author : J. Raub
ISBN : 9241572132
Genre : Medical
File Size : 85. 75 MB
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Evaluates the risks to human health and the environment posed by exposure to carbon monoxide: a colorless, odorless gas produced by both natural and anthropogenic processes. Concerns about the potential health effects of exposure have been addressed in extensive studies with both humans and a range of animal species. Although studies of carbon monoxide poisoning are included, the report gives major attention to possible health risks linked to the relatively low concentrations that characterize most exposures. The report also aims to identify subpopulations that may be especially susceptible to adverse health effects. Close to 1000 references are included in this comprehensive assessment. Concerning environmental levels arising from human activities, highway vehicle emissions are considered the principal source followed by emissions from non-highway transportation sources other fuel combustion sources industrial processes and solid waste disposal. Evidence from monitoring stations supports the conclusion that environmental concentrations are declining, reflecting the efficacy of emission control devices on newer vehicles. The report also considers the factors that contribute to indoor concentrations with cigarette smoke singled out as a major source. A chapter on environmental distribution and transformation summarizes what is known about the environmental fate of carbon monoxide, its contribution to ozone production in the troposphere and its possible role in global warming. Sources of personal exposure are considered in the next chapter which concludes that the most important exposures for the general population occur in the vehicle and indoor macroenvironments. Several occupations involving an increased risk of high exposures are also identified. Toxicokinetics and mechanisms of action are reviewed in the next chapter which discusses the many factors that influence the concentrations of carboxyhaemoglobin in blood and summarizes what is known about the primary mechanisms by which carboxyhaemoglobin formation exerts its toxic effects. The remaining chapters consider adverse effects on health. A review of the abundant findings from animal studies helps elucidate the mechanisms of carbon monoxide toxicity. Studies of developmental toxicity provide strong evidence that maternal exposure produces reductions in birth weight, cardiomegaly delays in behavioral development and disruptions in cognitive function. A chapter on health effects in humans considers numerous investigations of adverse effects linked to typical ambient exposure levels. Findings are summarized in terms of damage to the cardiovascular and respiratory systems effects on neurobehavioral functions, developmental toxicity and other systemic effects. Also considered are the effects of exposure at high altitudes in users of psychoactive drugs and in combination with exposure to other air pollutants. An evaluation of high-risk groups concludes that patients with reproducible exercise-induced ischaemia are a sensitive group at increased risk for experiencing adverse health effects. The report also found evidence indicating that exposure may cause an increased risk of sudden death from arrhythmia in patients with coronary artery disease. The report further concludes that exposure during pregnancy and early childhood carries a number of important risks. Concerning accidental exposure to high concentrations, the report concludes that carbon monoxide poisoning occurs frequently has severe consequences including immediate death involves complications and late sequelae and is often overlooked. Among its many other conclusions the report calls for better education of the general population about the risks of exposure especially in individuals with cardiovascular and respiratory disease and better awareness among medical professions of the dangers of carbon monoxide exposure during pregnancy.

Small Animal Critical Care Medicine

Author : Deborah Silverstein
ISBN : 9781416069263
Genre : Medical
File Size : 60. 33 MB
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Small Animal Critical Care Medicine is a comprehensive, concise guide to critical care, encompassing not only triage and stabilization, but also the entire course of care during the acute medical crisis and high-risk period. This clinically oriented manual assists practitioners in providing the highest standard of care for ICU patients. More than 150 recognized experts offer in-depth, authoritative guidance on clinical situations from a variety of perspectives. Consistent, user-friendly format ensures immediate access to essential information. Organ-system, problem-based approach incorporates only clinically relevant details. Features state-of-the-art invasive and non-invasive diagnostic and monitoring procedures, as well as an extensive section on pharmacology. Appendices provide conversion tables, continuous rate infusion determinations, reference ranges, and more.

Combined Exposures To Hydrogen Cyanide And Carbon Monoxide In Army Operations

Author : National Research Council
ISBN : 0309178681
Genre : Technology & Engineering
File Size : 90. 48 MB
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In response to a request from the U.S. Army, a committee convened by the National Research Council (NRC) conducted the first in a sequence of studies evaluating the combined health effects of low-level exposure to two chemicals Army personnel are likely to be exposed to in firing tank weapons. The Army sought information on whether the two chemicals, hydrogen cyanide and carbon monoxide, result in similar health impacts and should be assessed together when establishing exposure limits. Based on a review of the scientific literature, the report finds that the biochemical health impacts of the chemicals are similar and that the Army's proposed approach to setting exposure limits is appropriate. Because previous research has focused on high exposures, this initial NRC report recommends that futher neurological studies at low concentrations of exposure to the chemicals be conducted.

Carbon Monoxide And Human Lethality Fire And Non Fire Studies

Author : M.M. Hirschler
ISBN : 9781858610153
Genre : Science
File Size : 89. 30 MB
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This book summarizes a comprehensive study of the importance of carbon monoxide [CO] in fire atmospheres. It will be relevant to institutions involved in fire research, to industries producing combustible materials and to those concerned with fire from safety and medical standpoints.

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