chemistry of bioconjugates synthesis characterization and biomedical applications

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Chemistry Of Bioconjugates

Author : Ravin Narain
ISBN : 9781118776377
Genre : Science
File Size : 34. 69 MB
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Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. With its emphasis on synthesis, properties and applications, this book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials. Its detailed descriptions of methods make it possible for researchers to fabricate and take full advantage of bioconjugates for a broad range of applications. Moreover, the book sets the foundation for the development of new applications, including assays, imaging, biosensors, drug delivery, and diagnostics. Chemistry of Bioconjugates features contributions from an international team of leading experts and pioneers in the field. These contributions reflect the authors’ firsthand laboratory experience as well as a thorough review of the current literature. The book’s six sections examine: General methods of bioconjugation Polymer bioconjugates Organic nanoparticle-based bioconjugates Inorganic nanomaterial bioconjugates, including metals and metal oxides Cell-based, hydrogel/microgel, and glyco-bioconjugates Characterization, physico-(bio)chemical properties, and applications of bioconjugates This comprehensive exploration of bioconjugates includes discussions of polymers, dendrimers, lipids, nanoparticles, and nanotubes. References at the end of each chapter serve as a gateway to the most important original research findings and reviews in the field. By drawing together and analyzing all the latest chemical methods and research findings on the physico-chemical and biochemical properties of bioconjugates, Chemistry of Bioconjugates sheds new light on the significance and potential of bioconjugation. The book is recommended for organic and polymer chemists, biochemists, biomaterial scientists, carbohydrate chemists, biophysicists, bioengineers, and drug and gene delivery scientists.

Chemoselective And Bioorthogonal Ligation Reactions

Author : W. Russ Algar
ISBN : 9783527683475
Genre : Technology & Engineering
File Size : 44. 7 MB
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This timely, one-stop reference is the first on an emerging and interdisciplinary topic. Covering both established and recently developed ligation chemistries, the book is divided into two didactic parts: a section that focuses on the details of bioorthogonal and chemoselective ligation reactions at the level of fundamental organic chemistry, and a section that focuses on applications, particularly in the areas of chemical biology, biomaterials, and bioanalysis, highlighting the capabilities and benefits of the ligation reactions. With chapters authored by outstanding scientists who range from trailblazers in the field to young and emerging leaders, this book on a highly interdisciplinary topic will be of great interest for biochemists, biologists, materials scientists, pharmaceutical chemists, organic chemists, and many others.

Biomedical Applications Of Polymeric Materials And Composites

Author : Raju Francis
ISBN : 9783527690947
Genre : Technology & Engineering
File Size : 68. 32 MB
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With its content taken from only the very latest results, this is an extensive summary of the various polymeric materials used for biomedical applications. Following an introduction listing various functional polymers, including conductive, biocompatible and conjugated polymers, the book goes on to discuss different synthetic polymers that can be used, for example, as hydrogels, biochemical sensors, functional surfaces, and natural degradable materials. Throughout, the focus is on applications, with worked examples for training purposes as well as case studies included. The whole is rounded off with a look at future trends.

Engineered Carbohydrate Based Materials For Biomedical Applications

Author : Ravin Narain
ISBN : 9781118002247
Genre : Technology & Engineering
File Size : 51. 95 MB
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This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.

Semiconductor Nanomaterials

Author : Challa S. S. R. Kumar
ISBN : 9783527321667
Genre : Science
File Size : 30. 5 MB
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The must-have ten-volume successor to the critically acclaimed Nanotechnologies for the Life Sciences series, Nanomaterials for the Life Sciences, 10 Volume Set provides an excellent, in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis strategies, structure-property relationships, material behavior fine-tuning, biological effects, and applications in the life sciences. This landmark set provides materials scientists, chemists, biologists, molecular biologists, clinical physicists, physiological chemists, medicinal chemists, and toxicologists with essential awareness of life science applications.

Nanocomposite Particles For Bio Applications

Author : Tito Trindade
ISBN : 9789814267786
Genre : Medical
File Size : 60. 17 MB
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This book provides a concise state of the art of the synthesis and properties of nanocomposite particles with interest for diverse bio-applications. Contributions are mainly related to the chemical design of nanocomposite particles, their properties as well as their constituent materials, and the tailoring of bio-interfaces that may be relevant to the fields of clinical diagnosis and drug delivery procedures, among other bio-applications.

Polymers For Biomedical Applications

Author : Anil Mahapatro
ISBN : UOM:39015075620875
Genre : Science
File Size : 22. 57 MB
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The aging of the "baby boomers" population and the focus on health issues continues to drive the demand for better medical devices and health care solutions. Significant developments over the last two decades particularly in the field of biomaterials have revolutionized the biomaterials-based health care industry. Polymers represent the largest and most promising class of biomaterials based on their wide spread use in various medical applications. A large number of polymeric biomaterials have been developed and new developments continue to appear in journals and patent literatures. Although several excellent books and reviews cover specific areas in this interdisciplinary field; not many books strive to cover a comprehensive overview to the wide applications of polymers in the medical industry. Also, due to the significant growth of research and new technological advancements in biomaterials, this creates a need for updated and revised books within few years. This book covers some of the recent research developments in the field of polymeric biomaterials and their biomedical applications with a particular emphasis on work presented in the symposium entitled "Polymers for Biomedical Applications". The Book starts with a review of the synthesis of new and improved biomaterials and continues with a survey of the various tools and characterization techniques that are being used to characterize the polymeric biomaterials. Later, specific applications are discussed; such as applications of polymers for controlled release of bioactive agents, reactive coatings for biological applications, scaffolds for tissue engineering and as a base material for development of medical devices and biosensors.

Bioconjugation Protocols

Author : Christof M. Niemeyer
ISBN : 9781592598137
Genre : Medical
File Size : 56. 2 MB
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Expert laboratorians update the classic bioconjugation methods and introduce valuable new techniques that go beyond pure biomedical applications to include elements from advanced organic synthesis, molecular biology, and materials science. These readily reproducible methods cover the preparation of protein conjugates using covalent and noncovalent conjugation, the synthesis of nucleic acid conjugates using a variety of labeling techniques, and approaches to semisynthetic conjugates of proteins. Additional chapters address the biofunctionalization of inorganic surfaces, including the on-chip synthesis of peptide nucleic acids to generate microarrays for the high-throughput analysis of RNA and DNA, gold nanaoparticles, and carbon nanotube probes for atomic force microscopy.

Inorganic Nanoprobes For Biological Sensing And Imaging

Author : Hedi Mattoussi
ISBN : 9781596931978
Genre : Technology & Engineering
File Size : 56. 5 MB
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This groundbreaking resource offers you an up-to-date account of the pioneering activity pushing new boundaries in the emerging area of inorganic nanoprobes and their use in biology and medicine. Written and edited by leading experts in the field, this unique book places particular emphasis nanoprobes made of luminescent semiconductor nanocrystals (quantum dots or QDs) and magnetic nanoparticles (MNPs). You find an insightful discussion on the synthesis, characterization, and analysis of the unique properties of luminescent QDs and MNPs.

Cationic Polymers In Regenerative Medicine

Author : Sangram Keshari Samal
ISBN : 9781782620105
Genre : Technology & Engineering
File Size : 42. 69 MB
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The unique physico-chemical properties of cationic polymers and their ability to be easily modified make them attractive for many biological applications. As a result there is a vast amount of research focussed on designing novel natural or synthetic cationic polymers with specific biological functionality. Cationic Polymers in Regenerative Medicine brings together the expertise of leading experts in the field to provide a comprehensive overview of the recent advances in cationic polymer synthesis, modification and the design of biomaterials with different structures for therapeutic applications. Chapters cover recent developments in novel cationic polymer based systems including poly(L-lysine), Poly(N,N-dimethylaminoethyl methacrylate) and cationic triazine dendrimers as well as cationic polymer-coated micro- and nanoparticles and cationic cellulose and chitin nanocrystals. Applications discussed in the book include drug and gene delivery, therapeutics in thrombosis and inflammation as well as gene therapy. Suitable both for an educational perspective for those new to the field and those already active in the field, the book appeals to postgraduates and researchers. The broad aspects of the topics covered are suitable for polymer chemists interested in the fundamentals of the materials systems as well as pharmaceutical chemists, bioengineering and medical professionals interested in their applications.

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