cognitive impairment in schizophrenia

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Cognitive Impairment In Schizophrenia

Author : Philip D. Harvey
ISBN : 9781107013209
Genre : Medical
File Size : 53. 90 MB
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Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.

Cognition In Schizophrenia

Author : Tonmoy Sharma
ISBN : UOM:39015050012973
Genre : Medical
File Size : 48. 28 MB
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Although it has been known for 100 years that cognitive functioning is impaired in schizophrenia, the implications of this impairment have only recently been clearly understood. While in the past, cognitive deficits were thought to be the result of other aspects of the illness, such as poorco- operation, or as a result of the treatment of the illness, it is now known that these factors exert only a very minor influence on cognitive deficit. This book, with contributions from the major international names in the field, reviews the most recent research on the impairment of cognitivefunctioning in schizophrenia, covering: what it is, how wide-ranging it can be, what the clinical implications are, and how it can be treated? The book is divided into three sections. The first section provides background information on the important aspects of cognitive functioning inschizophrenia. The second section provides information on the correlates of cognitive functioning, examining classical symptoms of the illness, as well as social and adaptive functional deficits. The final section provides information on the treatment of cognitive functioning in schizophrenia,from the older less effective treatments with conventional antipsychotics, to the developing treatment strategies using experimental compounds. A clear insight into cognitive deficit is the key to understanding why previous treatments have failed, and the key by which new treatments may change thisterrible illness, treatments significantly more effective than earlier interventions.

Cognitive Deficits In Schizophrenia And Other Neuropsychiatric Disorders Convergence Of Preclinical And Clinical Evidence

Author : Ales Stuchlik
ISBN : 9782889196791
Genre :
File Size : 74. 25 MB
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Neuropsychiatric diseases, such as schizophrenia, Alzheimer's disease, and etc., represent a serious medical and socioeconomic problems. These diseases are often accompanied by impairments of cognitive function, e.g., abstract thinking, decision-making, attention, and several types of memory. Such deficits significantly disrupt quality of life and daily functioning of patients. Cognitive deficits in neuropsychiatric diseases are associated with alterations of brain morphology and function, and are often resistant to therapeutic interventions. In schizophrenia and related disorders, cognitive deficits are also defined as endophenotypes, i.e. measurable phenotypes linking these disaeses with discrete heritable and reproducible traits. This points to the importance of elucidating these endophenotypes in translational studies. Animal models may not mimic the full spectrum of clinical symptoms, but may act as analogies of particular behaviors or other pathological outcomes. They are useful to search for the etiology of particular psychiatric illnesses and novel therapeutics. Moreover, several behavioral tests to measure cognitive performance in rodents and other species have been implemented. The primary focus of the present topic is to provide up-to-date information on cognitive deficits of neuropsychiatric disorders, such as schizophrenia. This Research Topic also delineates future directions for translational studies aimed at developing novel treatments/interventions of cognitive disturbances.

Cognitive Remediation For Psychological Disorders

Author : Alice Medalia
ISBN : 9780190608453
Genre : Medical
File Size : 25. 13 MB
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"Cognitive Remediation for Psychological Disorders contains all the information therapists need to set up a cognitive remediation program that helps clients strengthen the cognitive skills necessary for everyday functioning"--

Social Cognition And Metacognition In Schizophrenia

Author : Paul Lysaker
ISBN : 9780124051744
Genre : Psychology
File Size : 66. 29 MB
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Deficits in social cognition and metacognition in schizophrenics makes it difficult for them to understand the speech, facial expressions and hence emotion and intention of others, as well as allowing little insight into their own mental state. These deficits are associated with poor social skills, fewer social relationships, and are predictive of poorer performance in a work setting. Social Cognition and Metacognition in Schizophrenia reviews recent research advances focusing on the precise nature of these deficits, when and how they manifest themselves, what their effect is on the course of schizophrenia, and how each can be treated. These deficits may themselves be why schizophrenia is so difficult to resolve; by focusing on the deficits, recovery may be quicker and long lasting. This book discusses such deficits in early onset, first episode, and prolonged schizophrenia; how the deficits relate to each other and to other forms of psychopathology; how the deficits affect social, psychological, and vocational functioning; and how best to treat the deficits in either individual or group settings. Summarizes the types of social cognitive and metacognitive deficits present in schizophrenia Discusses how deficits are related to each other and to other forms of psychopathology Describes how deficits impact function and affect the recovery process Provides treatment approaches for these deficits

The American Psychiatric Publishing Textbook Of Schizophrenia

Author : Jeffrey A. Lieberman
ISBN : 9781585626465
Genre : Medical
File Size : 89. 84 MB
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Although there are many books that consider aspects of schizophrenia such as research or clinical care, now there is a single resource that puts the many facets of this widely misunderstood disorder in perspective. The American Psychiatric Publishing Textbook of Schizophrenia offers broad coverage that encompasses the current state of knowledge the cause, nature, and treatment of schizophrenia. Experts in a wide range of disciplines from North America and Europe have contributed chapters that address the complexity of schizophrenia in a comprehensive volume on this singularly perplexing mental illness. No disorder is more challenging to psychiatrists and mental health care providers than schizophrenia, a condition that robs people of their personality and intellect and leaves them permanently disabled. This book leads readers through the maze of questions surrounding the disorder, from historical overview and epidemiology to consideration of comorbid conditions. It covers both genetic and environmental causes, describes all of the leading theories of schizophrenia -- neurodevelopmental, neurochemical, phospholipid, and neuroprogressive -- and explores the involvement of abnormal brain circuitry and the results of the latest neuroimaging studies. For practicing clinicians, the topics covered represent the most essential, timely, and informative insights for treating this most prototypic of mental illnesses: Approaching cognitive impairment as a potential psychopharmacological target for treatment, plus treatment strategies for improving functioning in individuals with social or vocational impairment. An overview of selected antipsychotic drugs -- including common side effects -- as well as antianxiety/hypnotics, antidepressants, mood stabilizers, and dopamine agonists. A review of current proven psychosocial interventions designed to augment and complement drug therapy, highlighting the trend toward optimizing patient preference in the choice of treatment modality. Keys to early identification of individuals vulnerable to psychoses and to assessing the potential for intervention with the promise of treatment earlier in life. Optimal treatment approaches for first episodes -- including individual, group, and family therapies -- to increase the likelihood of full recovery. Special considerations for treatment of chronic schizophrenia, addressing frequently asked questions faced by psychiatrists in their daily encounters with patients. While its causes and cure remain elusive, schizophrenia can be better understood with the help of the authoritative knowledge collected in these pages. Squarely confronting a disease that has long afflicted and baffled human society, this textbook will serve as a dependable source of knowledge for a generation of students, scientists, and clinicians to come.

Novel Antischizophrenia Treatments

Author : Mark A. Geyer
ISBN : 9783642257582
Genre : Medical
File Size : 83. 41 MB
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This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.

Modeling The Psychopathological Dimensions Of Schizophrenia

Author : Mikhail Pletnikov
ISBN : 9780128011843
Genre : Medical
File Size : 82. 96 MB
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Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader’s understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia Edited and authored by leading researchers in the field of schizophrenia and related psychoses

The Cognitive Neuropsychology Of Schizophrenia Classic Edition

Author : Christopher Donald Frith
ISBN : 9781317608301
Genre : Psychology
File Size : 25. 66 MB
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This is a classic edition of Christopher Frith’s award winning book on cognitive neuropsychology and schizophrenia, which now includes a new introduction from the author. The book explores the signs and symptoms of schizophrenia using the framework of cognitive neuropsychology, looking specifically at the cognitive abnormalities that underlie these symptoms. The book won the British Psychological Society book award in 1996, and is now widely seen as a classic in the field of brain disorders. The new introduction sees the author reflect on the influence of his research and the subsequent developments in the field, more than 20 years since the book was first published.

Neurocognition And Social Cognition In Schizophrenia Patients

Author : V. Roder
ISBN : 9783805593397
Genre : Psychology
File Size : 29. 69 MB
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Research shows that neuro- and social cognition have a decisive influence on functional outcome in people with schizophrenia. In this publication, world-renowned experts summarize the latest research on approaches to assessing and treating cognition in schizophrenia. The book is organized to take the reader through the steps from definitions and assessment of cognition to research on the relevance of cognition in everyday life, to chapters which focus on treatments for cognitive disorders. The reader will learn about the NIMH MATRICS initiative which has provided clinicians and researchers with the tools to define and assess neuro- and social cognitive functioning in people with schizophrenia. Then the treatments for neuro and social cognitive deficits are discussed in several chapters which give an overview of cognitive remediation approaches, accompanied by concrete treatment examples. The reader will also learn about the latest results of pharmacological interventions for cognitive deficits. A final chapter focuses on the importance of addressing motivational deficits when treating cognition, and offers treatment approaches to enhance motivation. This publication is essential reading for clinicians and researchers in the fields of psychiatry, psychology as well as students and other professions working with people who have schizophrenia.

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