cytokines stress and immunity

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Author : Robert E. Faith
ISBN : 9781420003802
Genre : Medical
File Size : 59. 56 MB
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Cytokine involvement in the immune system's response to stress is now very well documented. Cytokine activity has been implicated in a variety of mental and physical diseases, and has been shown to have a significant role in fueling the vicious circle of depression and illness. The first edition of Cytokines: Stress and Immunity pointed out that the immune system does not stand alone, but is profoundly affected by other organ systems, especially the central nervous and the neuroendocrine systems, with cytokines being the common tool of communication. This edition continues on the trailblazing path of the original to once again present current research that informs our evolving understanding of how cytokines function and the clinical implications of cytokine activity. Completely rewritten by the top authorities in their fields, this volume includes 16 entirely new chapters, which document dramatic new developments. It provides a comprehensive overview of the role of cytokines in the neuroendocrine and immune systems, while also addressing the interactions between these systems. It examines cytokine activity and clinical implications from a number of perspectives, including those of immunology, pharmacology, oncology, endocrinology, and psychiatry. Researchers involved with the most specific aspects of cell signaling as well clinicians dealing with the effects of immunosuppression-related diseases will find a wealth of interesting and instantly applicable information. This new edition begins with an extended dedication and tribute to the late Robert A. Good, the father of modern immunology. It documents the life and groundbreaking achievements of Dr. Good who served as an editor for both the former and current editions of this work.

Cytokines Stress And Depression

Author : Robert Dantzer
ISBN : 9780585379708
Genre : Medical
File Size : 79. 64 MB
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Cytokines had been characterized in the early eighties as communication mole cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a pivotal role of some of these molecules in cell death by apoptosis, prompted the investigation of their involvement in several neurological diseases involving an inflammatory component, including multiple sclerosis, brain trauma, stroke, and Alzheimer's disease. This movement started in the late eighties, and the corresponding field of research, known as neuroimmunology, is presently booming. In psychiatry, however, the relationship between cytokines and mental disorders was much less evident and took longer to materialize. The first indication that cytokines might be involved in psychopathology came from cancerology and internal medicine.

Stress And Immunity

Author : Nicholas P. Plotnikoff
ISBN : 0849388457
Genre : Medical
File Size : 68. 11 MB
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Stress and Immunity introduces and updates the status of research on stress and immunity. Clinical aspects of stress and immunity are presented in the first 17 chapters and include discussions regarding the influence of depression disorders on immune functions and stress interrelationships with cancer, AIDS, Chronic Fatigue Syndrome, and Herpes Simplex infections. There is also a review of physical exercise and immunity. The second half of the book is devoted to discussions regarding basic research being conducted in the field of stress and immunity. This includes discussions on the interrelationships of the central nervous system and the immune system and research on stress hormones (e.g., enkephalins, endorphins) as they interrelate with the immune system. In addition, animal models for the study of stress and immunity are discussed. Psychiatrists, neurologists, psychologists, clinical psychologists, internists, immunologists, and researchers in psychosomatic disorders should consider this an essential reference volume.

Handbook Of Human Stress And Immunity

Author : Ronald Glaser
ISBN : 012285960X
Genre : Psychology
File Size : 63. 9 MB
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In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.

Inflammation And Immunity In Depression

Author : Bernhard Baune
ISBN : 9780128110744
Genre : Medical
File Size : 65. 8 MB
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Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

Stress And Immunity

Author : Inna B. Mertsalova
ISBN : 9781525501876
Genre : Self-Help
File Size : 70. 6 MB
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More Than a Book About Stress – A Self-Help Tool That Gathers All You Need to Know to Stay Healthy In recent years, we have gained increasing knowledge of the roles stress and stress hormones play in our health. It is amazing how the presentation of a stressor—whether in one event or a series of events—might involve us in appraising the environmental challenge and lead us to the “fight-or-flight” response on a physiological level. The idea that stress has only harmful effects does not draw a full picture of its role in our health and well-being. It is scientifically proven that stress and stress hormones not only have a negative impact on our bodies, but they also have potentially beneficial properties, aimed at mobilizing our immune system for fighting immunologic confrontations. How does this work? In Stress and Immunity, Dr. Inna B. Mertsalova illustrates how our immune system functions under exposure to stress. Understanding these processes can help us cope with stress and stay healthy. The book also includes a test to check how you cope with stress and the information about sleep habits, physical activities, and nutrition that are necessary for reducing your stress level. This book is a valuable empirically proven source of information about the bi-directional effects of stress on our immune system. This book is written for everyone who wants to understand how stress modifies our body causing illness. Also, this volume has a great potential as a supplemental reading material for graduate students in the broad range of medical education.

Immune Function In Sport And Exercise

Author : Michael Gleeson
ISBN : 9780443101182
Genre : Medical
File Size : 76. 1 MB
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This title is directed primarily towards health care professionals outside of the United States. Designed to help readers understand and evaluate the relationship between exercise, immune function and infection risk, this book presents evidence for the "J-shaped" relationship between exercise load and infection risk. It also describes the components of the human immune system and key functions that protect the body from disease, the impact of acute and chronic psychological stress on immune function, and practical guidelines for minimizing the risk of immunodepression and infection in athletes. Further chapters explore different ways of measuring immune function, as well as the effects of heavy training on innate and specific (acquired) immunity, exercise in environmental extremes, and nutrition. Connections between exercise, infection risk, and immune function in special populations (elderly, obese, diabetic and HIV patients) are also addressed. Authored by a team of highly experienced experts. The "J-shaped" relationship between exercise load and infection risk is described, backed by current research and evidence. Components of the immune system and normal immune function are explained in detail, as well as methods for measuring immune function. The impact of acute and chronic psychological stress on immune function is presented, along with suggestions for minimizing the risk of immunodepression and infection in athletes. The effects of heavy training, exercise in environmental extremes, and nutrition are discussed with regard to their impact on innate and specific (acquired) immunity. Immune function in special populations (elderly, obese, diabetic and HIV patients) is also addressed, exploring links between exercise and infection risk in these groups. Evidence-based coverage includes a list of references in each chapter, as well as suggestions for further reading that direct readers to important texts and review articles. Information is presented in an easily accessible format, following a logical progression of material. LEach chapter begins with a list of learning objectives and ends with a list of key points to reinforce learning. A glossary at the end of the book defines all key terms and abbreviations.

Fundamentals Of Psychoneuroimmunology

Author : Cai Song
ISBN : 0471986712
Genre : Medical
File Size : 48. 99 MB
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Fundamentals of Psychoneuroimmunology Cai Song University of British Columbia, Vancouver, Canada, and Brian E. Leonard National University of Ireland, Galway, Ireland The long-held concept that the nervous, endocrine and immune systems are separate entities has given way to a new understanding of human biology. Psychoneuroimmunology addresses the realisation that the neural, immune, and endocrine systems are inextricably linked and that the effects of each affect all-the systems work together as a complicated set of triggers and balances, an intertwining of the physiological and emotional states. Beginning with the fundamentals of immune and neuroendocrine function, Fundamentals of Psychoneuroimmunology explores the complexities of behavioural assessment, the basic types of immunity, the importance of immune cell redistribution in the response to challenges such as infection and stress, and the multifaceted roles of nerves, hormones and cytokines. This text provides a sound introduction to the field and also serves as a valuable reference to those more familiar with the subject. Fundamentals of Psychoneuroimmunology: * Is the first book to cover this rapidly growing speciality comprehensively * Provides a sound biological basis to the discipline * Covers topics from the biology of immune and neuroendocrine function to the future of psychoneuroimmunology This volume, by the author of the acclaimed Fundamentals of Psychopharmacology, will be an essential reference for psychiatrists, neurologists, neuroimmunologists, neuroendocrinologists and psychologists, and will, it is hoped, stimulate further exploration into this exciting area of research.

Cytokines And Mental Health

Author : Ziad Kronfol
ISBN : 9781461503231
Genre : Medical
File Size : 61. 1 MB
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Cytokines and Mental Health explores the relationship between cytokines, neural circuitry and mental health. It is interdisciplinary and "translational", bringing together information that spans the spectrum from the molecular and cellular levels to the patient and the clinic. Content includes chapters that discuss cytokine pathways in the brain, the neurochemical and neuroendocrine effects of cytokines, and the behavioral effects of cytokines including sickness behavior. These chapters in basic research are followed by a more clinical section that discusses the role of cytokines in neuropsychiatric disorders such as major depression, schizophrenia and Alzheimer's disease. The book offers different things to different people. It should be of great interest to neuroscientists and immunologists working in the field of psychoneuroimmunology. It would also greatly benefit mental health professionals including psychiatrists, psychologists and clinicians of diverse background who are interested in mind-body medicine.

Mind Immunity And Health

Author : Phil Evans
ISBN : CORNELL:31924087299370
Genre : Psychology
File Size : 61. 78 MB
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There is a growing consensus that the mind can affect the immune system and over the past decade a new field - known as psychoneuroimmunology or PNI for short - has established itself to investigate the effects of the mind upon the immune system and vice versa. The authors of this exciting new area of research in the field of health psychology provide a comprehensive and detailed account informed by the latest research. Topics covered are stress and immunity, depression and immunity and assessment of the evidence that PNI effects are directly related to health.

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