diffuse optical tomography principles and applications

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Diffuse Optical Tomography

Author : Huabei Jiang
ISBN : 1439847584
Genre : Science
File Size : 22. 59 MB
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Written by an authority involved in the field since its nascent stages, Diffuse Optical Tomography: Principles and Applications is a long-awaited profile of a revolutionary imaging method. Diffuse Optical Tomography (DOT) provides spatial distributions of intrinsic tissue optical properties or molecular contrast agents through model-based reconstruction algorithms using NIR measurements along or near the boundary of tissue. Despite the practical value of DOT, many engineers from electrical or applied mathematics backgrounds do not have a sufficient understanding of its vast clinical applications and portability value, or its uncommon advantages as a tool for obtaining functional, cellular, and molecular parameters. A collection of the author’s research and experience, this book fuses historical perspective and experiential anecdotes with fundamental principles and vital technical information needed to successfully apply this technology—particularly in medical imaging. This reference finally outlines how to use DOT to create experimental image systems and adapt the results of laboratory studies for use in clinical applications including: Early-stage detection of breast tumors and prostate cancer "Real-time" functional brain imaging Joint imaging to treat progressive diseases such as arthritis Monitoring of tumor response New contrast mechanisms and multimodality methods This book covers almost every aspect of DOT—including reconstruction algorithms based on nonlinear iterative Newton methods, instrumentation and calibration methods in both continuous-wave and frequency domains, and important issues of imaging contrast and spatial resolution. It also addresses phantom experiments and the development of various image-enhancing schemes, and it describes reconstruction methods based on contrast agents and fluorescence DOT. Offering a concise description of the particular problems involved in optical tomography, this reference illustrates DOT’s fundamental foundations and the principle of image reconstruction. It thoroughly explores computational methods, forward mathematical models, and inverse strategies, clearly illustrating solutions to key equations.

Quantitative Biomedical Optics

Author :
ISBN : 9780521876568
Genre :
File Size : 74. 66 MB
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Molecular Imaging

Author : Markus Rudin
ISBN : 9781783260379
Genre : Science
File Size : 76. 18 MB
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Molecular imaging is a rapidly emerging field that translates many concepts developed for molecular biology and cellular imaging to the in vivo imaging of intact organisms. The technique allows the study of molecular biological events in their full context and will therefore become an indispensable tool for biomedical research and drug discovery and development. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities and the design of target reporter constructs are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events: the biodistribution of drugs/ligands, the expression of drug targets (receptors, enzymes), and the consequences of the molecular drug-target interactions (pathway activations, system responses). A final chapter deals with visualization of cell migration (cell therapies). Contents: Methodologies:Imaging TechniquesMolecular Reporter Systems, Design of Molecular Imaging ProbesApplications:Drug ImagingImaging Gene ExpressionImaging the Function of Gene ProductsMonitoring of Cell Migration Readership: Academics (medicine, pharmacology, biomedical technology) and industry (pharmaceutical, diagnostic, biomedical technology). Key Features:Written in a textbook manner, it is handy for students and newcomers to the field who wish to learn the basic concepts of molecular imagingThis book is perhaps the first of its kind to cover the topic as comprehensively as possible for an evolving technologyKeywords:Molecular Imaging;Magnetic Resonance Imaging;Positron-Emission Tomogrpahy;Near-Infrared Fluorescence Imaging;Bioluminescence Imaging;Ultrasound Imaging;Drug Biodistribution and Pharmacokinetics

Biomedical Optical Imaging Technologies

Author : Rongguang Liang
ISBN : 9783642283918
Genre : Science
File Size : 77. 51 MB
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This book provides an introduction to design of biomedical optical imaging technologies and their applications. The main topics include: fluorescence imaging, confocal imaging, micro-endoscope, polarization imaging, hyperspectral imaging, OCT imaging, multimodal imaging and spectroscopic systems. Each chapter is written by the world leaders of the respective fields, and will cover: principles and limitations of optical imaging technology, system design and practical implementation for one or two specific applications, including design guidelines, system configuration, optical design, component requirements and selection, system optimization and design examples, recent advances and applications in biomedical researches and clinical imaging. This book serves as a reference for students and researchers in optics and biomedical engineering.

Principles And Applications Of Magnetic Particle Imaging

Author : Bernhard Gleich
ISBN : 9783658019617
Genre : Medical
File Size : 76. 66 MB
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Bernhard Gleich introduces Magnetic Particle Imaging (MPI) including all aspects that are necessary for a complete understanding. MPI is a new imaging modality invented by Bernhard Gleich and Jürgen Weizenecker. The method is capable of imaging the distribution of superparamagnetic iron oxide particles (SPIOs) with high sensitivity, high spatial resolution, and high imaging speed. The author summarizes the results of a number of original papers and countless innovations he has elaborated in the young discipline of magnetic particle imaging.

Optical Imaging For Biomedical And Clinical Applications

Author : Ahmad Fadzil Mohamad Hani
ISBN : 9781315351384
Genre : Medical
File Size : 71. 42 MB
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Optical imaging is a rapidly emerging imaging technique that has been successfjully translated into biomedical applications ranging from clinical diagnosis to molecular biology. This book includes an introductory section to explore various optical imaging devices and their functionality and roles for biomedical applications such as dermatology and ophthalmology. Recent developments as exemplified with the authors research are explored in detail. In depth discussion of other disease conditions and their diagnosis with optical imaging techniques are also covered.

Molecular Imaging

Author : Ralph Weissleder
ISBN : 1607950057
Genre : Medical
File Size : 72. 47 MB
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The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Biomedical Optics

Author : Lihong V. Wang
ISBN : 9780470177006
Genre : Science
File Size : 89. 17 MB
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This entry-level textbook, covering the area of tissue optics, is based on the lecture notes for a graduate course (Bio-optical Imaging) that has been taught six times by the authors at Texas A&M University. After the fundamentals of photon transport in biological tissues are established, various optical imaging techniques for biological tissues are covered. The imaging modalities include ballistic imaging, quasi-ballistic imaging (optical coherence tomography), diffusion imaging, and ultrasound-aided hybrid imaging. The basic physics and engineering of each imaging technique are emphasized. A solutions manual is available for instructors; to obtain a copy please email the editorial department at ialine@wiley.com.

Optical And Digital Image Processing

Author : Gabriel Cristobal
ISBN : 9783527635252
Genre : Technology & Engineering
File Size : 87. 96 MB
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In recent years, Moore's law has fostered the steady growth of the field of digital image processing, though the computational complexity remains a problem for most of the digital image processing applications. In parallel, the research domain of optical image processing has matured, potentially bypassing the problems digital approaches were suffering and bringing new applications. The advancement of technology calls for applications and knowledge at the intersection of both areas but there is a clear knowledge gap between the digital signal processing and the optical processing communities. This book covers the fundamental basis of the optical and image processing techniques by integrating contributions from both optical and digital research communities to solve current application bottlenecks, and give rise to new applications and solutions. Besides focusing on joint research, it also aims at disseminating the knowledge existing in both domains. Applications covered include image restoration, medical imaging, surveillance, holography, etc... "a very good book that deserves to be on the bookshelf of a serious student or scientist working in these areas." Source: Optics and Photonics News

Webb S Physics Of Medical Imaging Second Edition

Author : M A Flower
ISBN : 9781466568952
Genre : Science
File Size : 88. 37 MB
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Since the publication of the best-selling, highly acclaimed first edition, the technology and clinical applications of medical imaging have changed significantly. Gathering these developments into one volume, Webb’s Physics of Medical Imaging, Second Edition presents a thorough update of the basic physics, modern technology and many examples of clinical application across all the modalities of medical imaging. New to the Second Edition Extensive updates to all original chapters Coverage of state-of-the-art detector technology and computer processing used in medical imaging 11 new contributors in addition to the original team of authors Two new chapters on medical image processing and multimodality imaging More than 50 percent new examples and over 80 percent new figures Glossary of abbreviations, color insert and contents lists at the beginning of each chapter Keeping the material accessible to graduate students, this well-illustrated book reviews the basic physics underpinning imaging in medicine. It covers the major techniques of x-radiology, computerised tomography, nuclear medicine, ultrasound and magnetic resonance imaging, in addition to infrared, electrical impedance and optical imaging. The text also describes the mathematics of medical imaging, image processing, image perception, computational requirements and multimodality imaging.

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