dynamic regression models for survival data statistics for biology and health

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Statistical And Methodological Aspects Of Oral Health Research

Author : Emmanuel Lesaffre
ISBN : 047074412X
Genre : Mathematics
File Size : 84. 65 MB
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Statistical and Methodological Aspects of Oral Health Research provides oral health researchers with an overview of the methodological aspects that are important in planning, conducting and analyzing their research projects whilst also providing biostatisticians with an idea of the statistical problems that arise when tackling oral health research questions. This collection presents critical reflections on oral health research and offers advice on practical aspects of setting up research whilst introducing the reader to basic as well as advanced statistical methodology. Features: An introduction to research methodology and an exposition of the state of the art. A variety of examples from oral health research. Contributions from well-known oral health researchers, epidemiologists and biostatisticians, all of whom have rich experience in this area. Recent developments in statistical methodology prompted by a variety of dental applications. Presenting both an introduction to research methodology and an exposition of the latest advances in oral health research, this book will appeal both beginning and experienced oral health researchers as well as biostatisticians and epidemiologists.

Dynamic Regression Models For Survival Data

Author : Torben Martinussen
ISBN : 9780387339603
Genre : Medical
File Size : 53. 23 MB
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This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and alternative models with the aim of describing time-varying effects of explanatory variables. Use of the suggested models and methods is illustrated on real data examples, using the R-package timereg developed by the authors, which is applied throughout the book with worked examples for the data sets.

Dynamic Regression Models For Survival Data

Author : Torben Martinussen
ISBN : 0387202749
Genre : Mathematics
File Size : 51. 5 MB
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In survival analysis there has long been a need for models that goes beyond the Cox model as the proportional hazards assumption often fails in practice. This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and alternative models with the specific aim of describing time-varying effects of explanatory variables. One model that receives special attention is Aalen’s additive hazards model that is particularly well suited for dealing with time-varying effects. The book covers the use of residuals and resampling techniques to assess the fit of the models and also points out how the suggested models can be utilised for clustered survival data. The authors demonstrate the practically important aspect of how to do hypothesis testing of time-varying effects making backwards model selection strategies possible for the flexible models considered. The use of the suggested models and methods is illustrated on real data examples. The methods are available in the R-package timereg developed by the authors, which is applied throughout the book with worked examples for the data sets. This gives the reader a unique chance of obtaining hands-on experience. This book is well suited for statistical consultants as well as for those who would like to see more about the theoretical justification of the suggested procedures. It can be used as a textbook for a graduate/master course in survival analysis, and students will appreciate the exercises included after each chapter. The applied side of the book with many worked examples accompanied with R-code shows in detail how one can analyse real data and at the same time gives a deeper understanding of the underlying theory. Torben Martinussen is at the Department of Natural Sciences at the Royal Veterinary and Agricultural University. He has a Ph.D. from University of Copenhagen and is associate editor of the Scandinavian Journal of Statistics. Thomas Scheike is at the Department of Biostatistics at University of Copenhagen. He has a Ph.D. from University of California at Berkeley and is Doctor of Science at the University of Copenhagen. He is the editor of the Scandinavian Journal of Statistics and associate editor of several other journals.

Dynamic Prediction In Clinical Survival Analysis

Author : Hans van Houwelingen
ISBN : 9781439835432
Genre : Mathematics
File Size : 22. 82 MB
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There is a huge amount of literature on statistical models for the prediction of survival after diagnosis of a wide range of diseases like cancer, cardiovascular disease, and chronic kidney disease. Current practice is to use prediction models based on the Cox proportional hazards model and to present those as static models for remaining lifetime after diagnosis or treatment. In contrast, Dynamic Prediction in Clinical Survival Analysis focuses on dynamic models for the remaining lifetime at later points in time, for instance using landmark models. Designed to be useful to applied statisticians and clinical epidemiologists, each chapter in the book has a practical focus on the issues of working with real life data. Chapters conclude with additional material either on the interpretation of the models, alternative models, or theoretical background. The book consists of four parts: Part I deals with prognostic models for survival data using (clinical) information available at baseline, based on the Cox model Part II is about prognostic models for survival data using (clinical) information available at baseline, when the proportional hazards assumption of the Cox model is violated Part III is dedicated to the use of time-dependent information in dynamic prediction Part IV explores dynamic prediction models for survival data using genomic data Dynamic Prediction in Clinical Survival Analysis summarizes cutting-edge research on the dynamic use of predictive models with traditional and new approaches. Aimed at applied statisticians who actively analyze clinical data in collaboration with clinicians, the analyses of the different data sets throughout the book demonstrate how predictive models can be obtained from proper data sets.

Analyzing Ecological Data

Author : Alain Zuur
ISBN : 9780387459721
Genre : Science
File Size : 64. 22 MB
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This book provides a practical introduction to analyzing ecological data using real data sets. The first part gives a largely non-mathematical introduction to data exploration, univariate methods (including GAM and mixed modeling techniques), multivariate analysis, time series analysis, and spatial statistics. The second part provides 17 case studies. The case studies include topics ranging from terrestrial ecology to marine biology and can be used as a template for a reader’s own data analysis. Data from all case studies are available from www.highstat.com. Guidance on software is provided in the book.

Reliability Life Testing And The Prediction Of Service Lives

Author : Sam C. Saunders
ISBN : 0387325220
Genre : Computers
File Size : 75. 9 MB
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This book is intended for students and practitioners who have had a calculus-based statistics course and who have an interest in safety considerations such as reliability, strength, and duration-of-load or service life. Many persons studying statistical science will be employed professionally where the problems encountered are obscure, what should be analyzed is not clear, the appropriate assumptions are equivocal, and data are scant. In this book there is no disclosure with many of the data sets what type of investigation should be made or what assumptions are to be used.

Mathematical Reviews

Author :
ISBN : UOM:39015076649915
Genre : Mathematics
File Size : 39. 44 MB
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