forward time population genetics simulations methods implementation and applications

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Forward Time Population Genetics Simulations

Author : Bo Peng
ISBN : 9781118180341
Genre : Science
File Size : 46. 49 MB
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The only book available in the area of forward-time populationgenetics simulations—applicable to both biomedical andevolutionary studies The rapid increase of the power of personal computers has led tothe use of serious forward-time simulation programs in geneticstudies. Forward-Time Population Genetics Simulationspresents both new and commonly used methods, and introducessimuPOP, a powerful and flexible new program that can be used tosimulate arbitrary evolutionary processes with unique features likecustomized chromosome types, arbitrary nonrandom mating schemes,virtual subpopulations, information fields, and Pythonoperators. The book begins with an overview of important concepts andmodels, then goes on to show how simuPOP can simulate a number ofstandard population genetics models—with the goal ofdemonstrating the impact of genetic factors such as mutation,selection, and recombination on standard Wright-Fisher models. Therest of the book is devoted to applications of forward-timesimulations in various research topics. Forward-Time Population Genetics Simulationsincludes: An overview of currently available forward-time simulationmethods, their advantages, and shortcomings An overview and evaluation of currently available software A simuPOP tutorial Applications in population genetics Applications in genetic epidemiology, statistical genetics, andmapping complex human diseases The only book of its kind in the field today, Forward-TimePopulation Genetics Simulations will appeal to researchers andstudents of population and statistical genetics.

Foundations Of Risk Analysis

Author : Terje Aven
ISBN : 9781119945789
Genre : Mathematics
File Size : 45. 39 MB
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Foundations of Risk Analysis presents the issues core to risk analysis – understanding what risk means, expressing risk, building risk models, addressing uncertainty, and applying probability models to real problems. The author provides the readers with the knowledge and basic thinking they require to successfully manage risk and uncertainty to support decision making. This updated edition reflects recent developments on risk and uncertainty concepts, representations and treatment. New material in Foundations of Risk Analysis includes: An up to date presentation of how to understand, define and describe risk based on research carried out in recent years. A new definition of the concept of vulnerability consistent with the understanding of risk. Reflections on the need for seeing beyond probabilities to measure/describe uncertainties. A presentation and discussion of a method for assessing the importance of assumptions (uncertainty factors) in the background knowledge that the subjective probabilities are based on A brief introduction to approaches that produce interval (imprecise) probabilities instead of exact probabilities. In addition the new version provides a number of other improvements, for example, concerning the use of cost-benefit analyses and the As Low As Reasonably Practicable (ALARP) principle. Foundations of Risk Analysis provides a framework for understanding, conducting and using risk analysis suitable for advanced undergraduates, graduates, analysts and researchers from statistics, engineering, finance, medicine and the physical sciences, as well as for managers facing decision making problems involving risk and uncertainty.

Forest Pathology And Plant Health

Author : Matteo Garbelotto
ISBN : 9783038426714
Genre : Science
File Size : 73. 18 MB
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This book is a printed edition of the Special Issue "Forest Pathology and Plant Health" that was published in Forests

Landscape Genetics

Author : Niko Balkenhol
ISBN : 9781118525241
Genre : Science
File Size : 54. 79 MB
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Despite the substantial interest in landscape genetics from the scientific community, learning about the concepts and methods underlying the field remains very challenging. The reason for this is the highly interdisciplinary nature of the field, which combines population genetics, landscape ecology, and spatial statistics. These fields have traditionally been treated separately in classes and textbooks, and very few scientists have received the interdisciplinary training necessary to efficiently teach or apply the diversity of techniques encompassed by landscape genetics. To address the current knowledge gap, this book provides the first in depth treatment of landscape genetics in a single volume. Specifically, this book delivers fundamental concepts and methods underlying the field, covering particularly important analytical methods in detail, and presenting empirical and theoretical applications of landscape genetics for a variety of environments and species. Consistent with the interdisciplinary nature of landscape genetics, the book combines an introductory, textbook like section with additional sections on advanced topics and applications that are more typical of edited volumes. The chapter topics and the expertise of the authors and the editorial team make the book a standard reference for anyone interested in landscape genetics. The book includes contributions from many of the leading researchers in landscape genetics. The group of scientists we have assembled has worked on several collaborative projects over the last years, including a large number of peer reviewed papers, several landscape genetics workshops at international conferences, and a distributed graduate seminar on landscape genetics. Based on the experiences gained during these collaborative teaching and research activities, the book includes chapters that synthesize fundamental concepts and methods underlying landscape genetics (Part 1), chapters on advanced topics that deserve a more in depth treatment (Part 2), and chapters illustrating the use of concepts and methods in empirical applications (Part 3). This structure ensures a high usefulness of the book for beginning landscape geneticists and experienced researchers alike, so that it has a broad target audience. At least one of the four co editors is involved in almost every chapter of the book, thereby ensuring a high consistency and coherency among chapters.

Pacific Symposium On Biocomputing

Author : Russ Altman
ISBN : 9812564632
Genre : Biology
File Size : 90. 31 MB
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The Pacific Symposium on Biocomputing (PSB) 2006 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2006 will be held January 3?7, 2006 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference. PSB 2006 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB has been designed to be responsive to the need for critical mass in

The Journal Of Cetacean Research And Management

Author :
ISBN : UCSD:31822009594870
Genre : Cetacea
File Size : 29. 63 MB
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Evolutionary Biology Of Bacterial And Fungal Pathogens

Author : Fernando Baquero
ISBN : UOM:39015076129124
Genre : Medical
File Size : 88. 30 MB
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This volume was inspired by the 2004 Fundacion Lilly conference that focused on the series of successive events characterizing the emergence, development, spread, variation, or disappearance of the interactions between microbes and humans resulting in a reduced fitness for the human host.

Dissertation Abstracts International

Author :
ISBN : STANFORD:36105131549631
Genre : Science
File Size : 70. 12 MB
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Hybrid Systems Computation And Control

Author : Rajeev Alur
ISBN : 9783540212591
Genre : Computers
File Size : 68. 49 MB
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This book constitutes the refereed proceedings of the 7th International Workshop on Hybrid Systems: Computation and Control, HSCC 2004, held in Philadelphia, PA, USA, in March 2004. The 43 revised full papers presented together with an invited article were carefully reviewed and selected from 117 submissions. The papers address all current issues in hybrid systems such as tools for analysis and verification, control and optimization, modeling and engineering applications, and emerging topics in programming language support and implementation; a special focus is on the interplay between biomolecular networks, systems biology, formal methods, and control of hybrid systems.

International Aerospace Abstracts

Author :
ISBN : STANFORD:36105021108068
Genre : Aeronautics
File Size : 21. 80 MB
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