genes environment and alzheimer s disease

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Genes Environment And Alzheimer S Disease

Author : Orly Lazarov
ISBN : 9780128028858
Genre : Medical
File Size : 67. 55 MB
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Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease. Provides the first volume to link genetic and environmental risk factors for Alzheimer’s disease and dementia Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer’s disease and cognitive decline Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists

Alzheimer S Disease

Author : Caroline McNeil
ISBN : 078813793X
Genre :
File Size : 74. 14 MB
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This report was written for people who are interested in research on Alzheimer's disease. Briefly covers the following areas of research: neurotransmitters, the proteins, the genes, environmental suspects, the calcium hypothesis, metabolism, cognitive markers, biological markers, caregiving, managing symptoms, potential biomedical treatments, and much more. Technical terms are defined in the glossary. Each chapter ends with a list of review articles and other materials that provide more detail on other studies mentioned in the text. Illustrated.

Alzheimer S Disease

Author : Adela Soliz
ISBN : 0737724420
Genre : Juvenile Nonfiction
File Size : 36. 11 MB
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Presents essays discussing Alzheimer's disease, including possible causes, research being done to find preventions or cures, and best ways to care for those with the disease.

Early Intervention In Psychiatry

Author : Peter Byrne
ISBN : 9781118387771
Genre : Medical
File Size : 58. 2 MB
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Early intervention (EI) is the single most important advance in mental health care in recent decades, representing a key shift in both theoretical standpoint and service delivery. Early Intervention in Psychiatry clearly describes best practice for extending this approach to all psychiatric disorders. Beginning with the rationale for EI, it informs interventions in people from all age groups across the lifespan, from perinatal to old age. It addresses EI in specific settings, such as primary health care, community health, the general hospital, non-government agencies, and in social movements, and for specific disorders including depression and anxiety, alcohol and substance use, childhood disorders, psychoses, bipolar disorders, eating disorders and borderline personality disorders. Early Intervention in Psychiatry is an essential guide for all psychiatrists, general practitioners, family physicians and public health doctors. It is also a valuable resource for mental health professionals and primary care colleagues, including nurses, social workers, psychologists, occupational therapists, vocational rehabilitation specialists, peer and support workers and for mental health commissioners and policy-makers.

Biomedical Index To Phs Supported Research Project Number Listing Investigator Listing

Author :
ISBN : MINN:31951P003778530
Genre : Medicine
File Size : 32. 82 MB
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Psychological Disorders

Author : Sonja. M. Lillrank
ISBN : 9781438118420
Genre : Dementia
File Size : 35. 22 MB
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Dementias are brain disorders that impair memory, thinking, and behavior, and Alzheimer's disease (AD) is the most common form, affecting 50 to 60 percent of dementia patients. Alzheimer's Disease and Other Dementias provides helpful clarification of this group of diseases and their specific types. Readers will learn how to recognize the symptoms of dementia or Alzheimer's disease, how these disorders are diagnosed, the latest theories about their cause, and how they can be treated. The book also directs attention to current research on the subject, the outlook for future prevention and treatment, and resources providing further information.

Research Progress In Alzheimer S Disease And Dementia

Author : Miao-Kun Sun
ISBN : 1600219608
Genre : Medical
File Size : 66. 88 MB
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Alzheimer's disease (AD), the most common form of neurodegenerative disorder in the elderly, is characterised pathologically by extracellular amyloid plaques and intracellular neurofibrillary tangles, pathophysiologically by synaptic dysfunction, and clinically by a progressive decline in cognition. Currently, AD has no cure and its prevalence is predicted to triple by 2050 with the rapid increase in the ageing population, unless more effective treatments are developed. Since the publication of the second book volume, the rapid progress in the research fields of AD and dementia continues through the intensive efforts of research scientists worldwide.This third book volume contains 15 chapters, bringing together a presentation of research frontiers in current AD/dementia research. The topics include molecular genetics of AD, gene expression abnormalities in AD progression, presenilins, taupathy in AD, single - induced(neuron gene expression abnormalities in AD, intracellular A neurodegeneration, roles of lipoprotein receptors in AD onset and progression, cholesterol and tau hyperphosphorylation, AD diagnostics and therapeutic strategies, in vivo visualisation of amyloid-like structures, cathepsin B, antiamyloidogenesis and neuroprotection, environmental enrichment, Fragile X mental retardation gene and dementia, category learning in Parkinson's disease, cerebrovascular disease and dementia, and dementia and hypertension.These chapters cover current advances in our understanding of the pathogenic mechanisms underlying AD and dementia, in the diagnosis of early AD and dementia, and in the development of therapeutic agents that target memory-relevant AD pathogenesis. The book will be highly valuable to students and scientists worldwide who are interested in the scientific research progress in AD and dementia.

Environmental Causes And Prevention Measures For Alzheimer S Disease

Author : George J. Brewer
ISBN : 9780128111635
Genre : Medical
File Size : 53. 90 MB
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Environmental Causes and Prevention Measures for Alzheimer’s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers. Emphasizes the history and epidemiology of Alzheimer’s disease, highlighting its epidemic proportions in developed countries Discusses data on new environmental factors in developed countries Provides prevention measures to potentially reduce Alzheimer’s rates through diet

Genotype Proteotype Phenotype Relationships In Neurodegenerative Diseases

Author : J. Cummings
ISBN : 3540248358
Genre : Medical
File Size : 73. 21 MB
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Neurodegenerative Disorders as Proteinopathies: Phenotypic Relationships.- Towards a Molecular Classification of Neurodegenerative Disease.- Racial and Ethnic Influences on the Expression of the Genotype in Neurodegenerative Diseases.- Causes and Consequences of Oxidative Stress in Neurodegenerative Diseases.- Early Onset Familial Alzheimer's Disease: Is a Mutation Predictive of Pathology?.- Identification of Genes that Modify the Age of Onset in a Large Familial Alzheimer's Disease Kindred.- Variable Phenotype of Alzheimer's Disease with Spastic Paraparesis.- Presenilin Mutations: Variations in the Behavioral Phenotype with an Emphasis on the Frontotemporal Dementia Phenoytpe.- Frontotemporal Dementias: Genotypes and Phenotypes.- Chromosome 17-Linked Frontotemporal Dementia with Ubiquitin-Positive, tau-Negative Inclusions.- Variations of the Phenotype in Frontotemporal Dementias.- Phenotype/Genotype Correlations in Parkinson's Disease.- Subject Index

Investigating Neurological Disease

Author : Albert Hofman
ISBN : 0521000092
Genre : Medical
File Size : 52. 74 MB
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This invaluable handbook for clinicians reviews the epidemiology, treatment and prognosis of all major diseases of the nervous system.

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