handbook of spatial epidemiology chapman hall crc handbooks of modern statistical methods

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Handbook Of Spatial Statistics

Author : Alan E. Gelfand
ISBN : 1420072889
Genre : Mathematics
File Size : 23. 17 MB
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Assembling a collection of very prominent researchers in the field, the Handbook of Spatial Statistics presents a comprehensive treatment of both classical and state-of-the-art aspects of this maturing area. It takes a unified, integrated approach to the material, providing cross-references among chapters. The handbook begins with a historical introduction detailing the evolution of the field. It then focuses on the three main branches of spatial statistics: continuous spatial variation (point referenced data); discrete spatial variation, including lattice and areal unit data; and spatial point patterns. The book also contains a section on space–time work as well as a section on important topics that build upon earlier chapters. By collecting the major work in the field in one source, along with including an extensive bibliography, this handbook will assist future research efforts. It deftly balances theory and application, strongly emphasizes modeling, and introduces many real data analysis examples.

Handbook Of Spatial Epidemiology

Author : Andrew B. Lawson
ISBN : 9781482253023
Genre : Mathematics
File Size : 41. 16 MB
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Handbook of Spatial Epidemiology explains how to model epidemiological problems and improve inference about disease etiology from a geographical perspective. Top epidemiologists, geographers, and statisticians share interdisciplinary viewpoints on analyzing spatial data and space–time variations in disease incidences. These analyses can provide important information that leads to better decision making in public health. The first part of the book addresses general issues related to epidemiology, GIS, environmental studies, clustering, and ecological analysis. The second part presents basic statistical methods used in spatial epidemiology, including fundamental likelihood principles, Bayesian methods, and testing and nonparametric approaches. With a focus on special methods, the third part describes geostatistical models, splines, quantile regression, focused clustering, mixtures, multivariate methods, and much more. The final part examines special problems and application areas, such as residential history analysis, segregation, health services research, health surveys, infectious disease, veterinary topics, and health surveillance and clustering. Spatial epidemiology, also known as disease mapping, studies the geographical or spatial distribution of health outcomes. This handbook offers a wide-ranging overview of state-of-the-art approaches to determine the relationships between health and various risk factors, empowering researchers and policy makers to tackle public health problems.

Handbook Of Graphical Models

Author : Marloes Maathuis
ISBN : 9780429874246
Genre : Mathematics
File Size : 27. 29 MB
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A graphical model is a statistical model that is represented by a graph. The factorization properties underlying graphical models facilitate tractable computation with multivariate distributions, making the models a valuable tool with a plethora of applications. Furthermore, directed graphical models allow intuitive causal interpretations and have become a cornerstone for causal inference. While there exist a number of excellent books on graphical models, the field has grown so much that individual authors can hardly cover its entire scope. Moreover, the field is interdisciplinary by nature. Through chapters by leading researchers from different areas, this handbook provides a broad and accessible overview of the state of the art. Key features: * Contributions by leading researchers from a range of disciplines * Structured in five parts, covering foundations, computational aspects, statistical inference, causal inference, and applications * Balanced coverage of concepts, theory, methods, examples, and applications * Chapters can be read mostly independently, while cross-references highlight connections The handbook is targeted at a wide audience, including graduate students, applied researchers, and experts in graphical models.

Handbook Of Statistical Methods And Analyses In Sports

Author : Jim Albert
ISBN : 9781351678964
Genre : Mathematics
File Size : 50. 15 MB
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This handbook will provide both overviews of statistical methods in sports and in-depth treatment of critical problems and challenges confronting statistical research in sports. The material in the handbook will be organized by major sport (baseball, football, hockey, basketball, and soccer) followed by a section on other sports and general statistical design and analysis issues that are common to all sports. This handbook has the potential to become the standard reference for obtaining the necessary background to conduct serious statistical analyses for sports applications and to appreciate scholarly work in this expanding area.

Handbook Of Approximate Bayesian Computation

Author : Scott A. Sisson
ISBN : 9781351643467
Genre : Mathematics
File Size : 71. 43 MB
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As the world becomes increasingly complex, so do the statistical models required to analyse the challenging problems ahead. For the very first time in a single volume, the Handbook of Approximate Bayesian Computation (ABC) presents an extensive overview of the theory, practice and application of ABC methods. These simple, but powerful statistical techniques, take Bayesian statistics beyond the need to specify overly simplified models, to the setting where the model is defined only as a process that generates data. This process can be arbitrarily complex, to the point where standard Bayesian techniques based on working with tractable likelihood functions would not be viable. ABC methods finesse the problem of model complexity within the Bayesian framework by exploiting modern computational power, thereby permitting approximate Bayesian analyses of models that would otherwise be impossible to implement. The Handbook of ABC provides illuminating insight into the world of Bayesian modelling for intractable models for both experts and newcomers alike. It is an essential reference book for anyone interested in learning about and implementing ABC techniques to analyse complex models in the modern world.

Handbook Of Methods For Designing Monitoring And Analyzing Dose Finding Trials

Author : John O'Quigley
ISBN : 9781351648028
Genre : Mathematics
File Size : 20. 85 MB
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Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted therapies, immunotherapy, combination treatments and complex group structures has provided the stimulus to these advances. Typically, we deal with very small samples, sequential methods that need to be efficient, while, at the same time adhering to ethical principles due to the involvement of human subjects. Statistical inference is difficult since the standard techniques of maximum likelihood do not usually apply as a result of model misspecification and parameter estimates lying on the boundary of the parameter space. Bayesian methods play an important part in overcoming these difficulties, but nonetheless, require special consideration in this particular context. The purpose of this handbook is to provide an expanded summary of the field as it stands and also, through discussion, provide insights into the thinking of leaders in the field as to the potential developments of the years ahead. With this goal in mind we present: An introduction to the field for graduate students and novices A basis for more established researchers from which to build A collection of material for an advanced course in early phase clinical trials A comprehensive guide to available methodology for practicing statisticians on the design and analysis of dose-finding experiments An extensive guide for the multiple comparison and modeling (MCP-Mod) dose-finding approach, adaptive two-stage designs for dose finding, as well as dose–time–response models and multiple testing in the context of confirmatory dose-finding studies.? John O’Quigley is a professor of mathematics and research director at the French National Institute for Health and Medical Research based at the Faculty of Mathematics, University Pierre and Marie Curie in Paris, France. He is author of Proportional Hazards Regression and has published extensively in the field of dose finding. Alexia Iasonos is an associate attending biostatistician at the Memorial Sloan Kettering Cancer Center in New York. She has over one hundred publications in the leading statistical and clinical journals on the methodology and design of early phase clinical trials. Dr. Iasonos has wide experience in the actual implementation of model based early phase trials and has given courses in scientific meetings internationally. Björn Bornkamp is a statistical methodologist at Novartis in Basel, Switzerland, researching and implementing dose-finding designs in Phase II clinical trials. He is one of the co-developers of the MCP-Mod methodology for dose finding and main author of the DoseFinding R package. He has published numerous papers on dose finding, nonlinear models and Bayesian statistics, and in 2013 won the Royal Statistical Society award for statistical excellence in the pharmaceutical industry. ? ?

Handbook Of Markov Chain Monte Carlo

Author : Steve Brooks
ISBN : 9781420079425
Genre : Mathematics
File Size : 72. 52 MB
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Since their popularization in the 1990s, Markov chain Monte Carlo (MCMC) methods have revolutionized statistical computing and have had an especially profound impact on the practice of Bayesian statistics. Furthermore, MCMC methods have enabled the development and use of intricate models in an astonishing array of disciplines as diverse as fisheries science and economics. The wide-ranging practical importance of MCMC has sparked an expansive and deep investigation into fundamental Markov chain theory. The Handbook of Markov Chain Monte Carlo provides a reference for the broad audience of developers and users of MCMC methodology interested in keeping up with cutting-edge theory and applications. The first half of the book covers MCMC foundations, methodology, and algorithms. The second half considers the use of MCMC in a variety of practical applications including in educational research, astrophysics, brain imaging, ecology, and sociology. The in-depth introductory section of the book allows graduate students and practicing scientists new to MCMC to become thoroughly acquainted with the basic theory, algorithms, and applications. The book supplies detailed examples and case studies of realistic scientific problems presenting the diversity of methods used by the wide-ranging MCMC community. Those familiar with MCMC methods will find this book a useful refresher of current theory and recent developments.

Kompendium Systembiologie

Author : Andreas Kremling
ISBN : 9783834886071
Genre : Science
File Size : 59. 75 MB
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Das Buch beschreibt die Grundlagen der mathematischen Modellierung zellulärer Systeme. Nach einer Klassifikation von Modellen wird schwerpunktmäßig auf deterministische Modelle eingegangen und für alle relevanten zellulären Prozesse entsprechende Gleichungen angegeben. Anschließend werden eine Reihe von Verfahren zur Modellanalyse vorgestellt. Etwas kürzer werden Verfahren zum Reverse Engineering und zur Analyse von Netzwerkgraphen abgehandelt. Am Ende werden noch Verfahren der Parameteridentifikation besprochen.

Analyse Von Zeitreihen

Author : Christopher Chatfield
ISBN : 3446135979
Genre :
File Size : 29. 99 MB
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Statistik F R Dummies

Author : Deborah J. Rumsey
ISBN : 9783527692767
Genre : Education
File Size : 48. 1 MB
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Statistik ist ganz sicher kein beliebtes, aber ein notwendiges und auch nï¿1⁄2tzliches Thema. Deborah Rumsey erklï¿1⁄2rt Ihnen in diesem Buch die notwendigen Grundbegriffe, erlï¿1⁄2utert die wichtigsten statistischen Konzepte und schafft einen Bezug zwischen Theorie und Praxis. Dabei kommt Sie fast ohne Formeln aus. Sie lernen die verschiedenen grafischen Darstellungsmï¿1⁄2glichkeiten von statistischem Material kennen und erfahren, wie Sie Ihre Ergebnisse richtig auswerten. Egal ob Mittelwert, Bias, Standardabweichung oder Konfidenzintervall, schon bald kann Ihnen keiner mehr etwas vormachen.

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