here is a human being at the dawn of personal genomics

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Here Is A Human Being

Author : Misha Angrist
ISBN : 9780062010469
Genre : Science
File Size : 33. 79 MB
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Here is a Human Being delivers the first in-depth look at the Personal Genome Project—the effort to construct complete genomic maps of a specific human beings—written by one of the study’s ten human participants. Misha Angrist recounts the project’s fascinating nuances, including the larger-than-life personalities of the research subjects, the entrepreneurial scientists at the helm, the bewildered and overwhelmed physicians and regulators who negotiated for it, the fascinating technology it employed, and the political, social, ethical and familial issues it continues to raise. In the vein of James Shreeve’s The Genome War, Craig J. Ventner’s My Life Decoded, and Francis J. Collins’ The Language of Life, Angrist’s informed exploration of this cutting-edge science is a gripping look at the present and future of genomics.

Biotechnology And Society

Author : Hallam Stevens
ISBN : 9780226046150
Genre : Science
File Size : 62. 29 MB
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With Biotechnology and Society, Hallam Stevens offers an up-to-date primer to help us understand the interactions of biotechnology and society and the debates, controversies, fears, and hopes that have shaped how we think about bodies, organisms, and life in the twenty-first century. Stevens addresses such topics as genetically modified foods, cloning, and stem cells; genetic testing and the potential for discrimination; fears of (and, in some cases, hopes for) designer babies; personal genomics; biosecurity; and biotech art. Taken as a whole, the book presents a clear, authoritative picture of the relationship between biotechnology and society today, and how our conceptions (and misconceptions) of it could shape future developments. It is an essential volume for students and scholars working with biotechnology, while still being accessible to the general reader interested in the truth behind breathless media accounts about biotech’s promise and perils.

Dna

Author : James D. Watson
ISBN : 9780385351188
Genre : Medical
File Size : 46. 26 MB
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Updated edition of: DNA: the secret of life.

One In A Billion

Author : Kathleen Gallagher
ISBN : 9781451661323
Genre : Biography & Autobiography
File Size : 88. 81 MB
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The breathtaking story of a young boy with a never-before-seen disease, and the doctors who take a bold step into the future of medicine to save him—based on the authors’ Pulitzer Prize–winning reporting. In this landmark medical narrative, in the tradition of The Immortal Life of Henrietta Lacks and The Spirit Catches You and You Fall Down, Pulitzer Prize–winning journalists Mark Johnson and Kathleen Gallagher chronicle the story of Nic Volker, the Wisconsin boy at the center of a daring breakthrough in medicine—a complete gene sequencing to discover the cure for an otherwise undiagnosable illness. At just two years old, Nic experienced a searing pain that signaled the awakening of a new and deadly disease, one that would hurl Nic and his family up against the limits of modern medicine. For years, through false starts and failed cures, Nic holds on to life, buoyed up by his mother’s fierce drive to get him the care he needs. But when even the world’s experts are stumped by Nic’s illness, his doctors come up with a radical, long-shot plan: a step into the unknown. The next major scientific frontier, following the completion of the Human Genome Project, was to figure out how to use our new knowledge to save lives—to bring genomic or personalized medicine into reality. It’s a quest that is undertaken by researchers around the world. But it is only when geneticist Howard Jacob hears about young Nic that the finish line finally comes into sight: It’s no longer a race to make history. It’s a race to save this boy’s life. One in a Billion is an unforgettable tale of the lives that converged to launch a medical revolution. As pioneering geneticist Mary-Claire King pronounced upon learning Nic’s story: “It was as if one had heard about Case Zero of AIDS and the cure, all at once.”

The Creative Destruction Of Medicine

Author : Eric J. Topol
ISBN : 9780465025503
Genre : Medical
File Size : 61. 37 MB
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A professor of medicine reveals how technology like wireless internet, individual data, and personal genomics can be used to save lives.

Regenesis

Author : George M. Church
ISBN : 9780465038657
Genre : Science
File Size : 31. 86 MB
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“Bold and provocative… Regenesis tells of recent advances that may soon yield endless supplies of renewable energy, increased longevity and the return of long-extinct species.”—New Scientist In Regenesis, Harvard biologist George Church and science writer Ed Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

Me Medicine Vs We Medicine

Author : Donna Dickenson
ISBN : 9780231534413
Genre : Medical
File Size : 47. 51 MB
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Personalized healthcare—or what the award-winning author Donna Dickenson calls "Me Medicine"—is radically transforming our longstanding "one-size-fits-all" model. Technologies such as direct-to-consumer genetic testing, pharmacogenetically developed therapies in cancer care, private umbilical cord blood banking, and neurocognitive enhancement claim to cater to an individual's specific biological character, and, in some cases, these technologies have shown powerful potential. Yet in others they have produced negligible or even negative results. Whatever is behind the rise of Me Medicine, it isn't just science. So why is Me Medicine rapidly edging out We Medicine, and how has our commitment to our collective health suffered as a result? In her cogent, provocative analysis, Dickenson examines the economic and political factors fueling the Me Medicine phenomenon and explores how, over time, this paradigm shift in how we approach our health might damage our individual and collective well-being. Historically, the measures of "We Medicine," such as vaccination and investment in public-health infrastructure, have radically extended our life spans, and Dickenson argues we've lost sight of that truth in our enthusiasm for "Me Medicine." Dickenson explores how personalized medicine illustrates capitalism's protean capacity for creating new products and markets where none existed before—and how this, rather than scientific plausibility, goes a long way toward explaining private umbilical cord blood banks and retail genetics. Drawing on the latest findings from leading scientists, social scientists, and political analysts, she critically examines four possible hypotheses driving our Me Medicine moment: a growing sense of threat; a wave of patient narcissism; corporate interests driving new niche markets; and the dominance of personal choice as a cultural value. She concludes with insights from political theory that emphasize a conception of the commons and the steps we can take to restore its value to modern biotechnology.

Cracking The Genome

Author : Kevin Davies
ISBN : 0801871409
Genre : Medical
File Size : 40. 80 MB
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This newly updated edition sheds light on the secrets of the sequence, highlighting the myriad ways in which genomics will impact human health for generations to come.

Biocode

Author : Dawn Field
ISBN : 9780199687756
Genre : Science
File Size : 65. 40 MB
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The living world runs on genomic software - what Dawn Field and Neil Davies call the 'biocode' - the sum of all DNA on Earth. In Biocode, they tell the story of a new age of scientific discovery: the growing global effort to read and map the biocode, and what that might mean for the future. The structure of DNA was identified in 1953, and the whole human genome was mapped by 2003. Since then the new field of genomics has mushroomed and is now operating on an industrial scale. Genomes can now be sequenced rapidly and increasingly cheaply. The genomes of large numbers of organisms from mammals to microbes, have been mapped. Getting your genome sequenced is becoming affordable for many. You too can check paternity, find out where your ancestors came from, or whether you are at risk of some diseases. Some check out the pedigree of their pets, while others turn genomes into art. A stray hair is enough to crudely reconstruct the face of the owner. From reading to constructing: the first steps to creating artificial life have already been taken. Some may find the rapidity of developments, and the potential for misuse, alarming. But they also open up unprecedented possibilities. The ability to read DNA has changed how we view ourselves and understand our place in nature. From the largest oceans, to the insides of our guts, we are able to explore the biosphere as never before, from the genome up. Sequencing technology has made the invisible world of microbes visible, and biodiversity genomics is revealing whole new worlds within us and without. The findings are transformational: we are all ecosystems now. Already the first efforts at 'barcoding' entire ecological communities and creating 'genomic observatories' have begun. The future, the authors argue, will involve biocoding the entire planet.

A Life Decoded

Author : J. Craig Venter
ISBN : 9781101202562
Genre : Biography & Autobiography
File Size : 28. 60 MB
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The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.

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