immunohistochemistry basics and methods

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Immunohistochemistry Basics And Methods

Author : Igor B. Buchwalow
ISBN : 3642046096
Genre : Medical
File Size : 43. 19 MB
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This concise yet comprehensive guide to the methods and protocols of immunohistochemistry covers established techniques and current developments in the field such as the use of epitope tags, multiple immunolabeling and diagnostic immunohistochemistry.

Basic Science Techniques In Clinical Practice

Author : Hitendra R.H. Patel
ISBN : 9781846287404
Genre : Medical
File Size : 25. 53 MB
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A complete guide to implementing research projects for anyone in the medical professions. This book covers all the main areas, allowing anyone to set up and complete research projects. The techniques outlined here can easily be adapted to clinical projects. Written by international authors to provide a flavor from many institutions, the book’s appeal is cross-sectional, both at hospital and primary care levels worldwide. Providing cutting-edge information in an accessible manner, and containing diagrams and easy-to-follow step-by-step guides, this is the first guide of its kind. It contains a complete section on setting up and funding research projects.


Author : Alexander E. Kalyuzhny
ISBN : 9783319308937
Genre : Science
File Size : 41. 61 MB
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Aimed at both beginners and experienced researchers unfamiliar with the technique, this book provides a concise and easy-to-understand guide to using immunohistochemistry. It identifies the proper place and purpose of each component of immunohistochemistry, emphasizes the components that are of critical importance, and explains the logistics of experimental approaches. Understanding the principles of immunohistochemistry allows for the identification and localization of protein targets and is of crucial use in the following experiments: · producing transgenic animals · studying the effects of drug treatments · electrophysiological studies · animal surgery · isolating and differentiating stem cells · super-resolution microscopy Immunohistochemistry for the Non-Expert is aimed at a wide audience, including molecular biologists, pharmacologists, immunologists, chemists, cell biologists, physiologists, and researchers involved with animal anatomy studies.

Toxicologic Pathology

Author : Pritam S. Sahota
ISBN : 9781439872123
Genre : Medical
File Size : 55. 77 MB
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As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Safety Assessment presents a histopathologic description of lesions observed during drug development and discusses their implication in the drug development process. Divided into two sections, the book systematically assists pathologists in making a determination as to the origin and potential importance of a lesion and its relevance for assessing human risk. The first section includes eight "concept" chapters to orient pathologists in areas that are important for effective interaction with other pathologists as well as the many non-pathologists involved in drug development. The second section is made up of organ-based chapters, each including light microscopic and electron microscopic descriptions of pathological lesions, differential diagnoses, biological consequences, pathogenesis, mechanism of lesion formation, and the expected clinical pathology correlates. This volume presents critical information—both published and unpublished and gained through personal experience—to improve the quality of drug safety evaluation and to expedite and improve the efficiency of the process. This book is crafted to assist students, residents, and toxicologic pathologists in their early career phase by serving as a resource that can effectively be used as a ready reference next to the microscope. In addition, more experienced pathologists will find this volume to be invaluable during their assessments. The book is also a valuable reference for toxicologists to assist in understanding compound-related pathological findings and to provide background for working on a range of toxicological problems.


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File Size : 33. 4 MB
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Neurogastroenterology From The Basics To The Clinics

Author : H.-J. Krammer
ISBN : 0792387570
Genre : Medical
File Size : 63. 80 MB
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In the last decade, some outstanding progress has been made in the field of neurogastroenterology, a term which has been introduced to account for the crucial role of the enteric, autonomic and central nervous system in the regulation of gastrointestinal functions in health and disease. These proceedings of Falk Symposium No. 112 on Neurogastroenterology - From the Basics to the Clinics, held in Freiburg, Germany, on 21-22 June 1999, reviews and discusses the fast-growing knowledge in this field in order to initiate more interdiscliplinary discussions along with new research. Contributors include basic scientists, clinicians of various specialities, morphologists, physiologists, molecular biologists, embryologists, pharmacologists, surgeons, gastroenterologists and behavioural scientists interested in the central and the autonomic nervous system in relation to the gastrointestinal tract.

Archives Of Pathology Laboratory Medicine

Author :
ISBN : NWU:35558005694936
Genre : Diagnosis, Laboratory
File Size : 77. 62 MB
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Author : Freida L. Carson
ISBN : 089189411X
Genre : Medical
File Size : 37. 19 MB
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(1E 1990) Includes electron microscopy histochemistry nuclear & cytoplasmic staining pigments & minerals etc.

In Situ Molecular Pathology And Co Expression Analyses

Author : Gerard J. Nuovo
ISBN : 9780124160019
Genre : Science
File Size : 60. 48 MB
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In Situ Molecular Pathology and Co-Expression Analyses explains, in easy-to-understand language, simplified ways of understanding and performing in situ hybridization and immunohistochemistry tests. The book also focuses on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. The fields of in situ hybridization and immunohistochemistry have expanded rapidly due to the use of computer-based analysis. To get the most out of these automated platforms, researchers and diagnostic biomedical investigators must have a solid understanding of the basics of in situ-based tests, protocols, and regimens for troubleshooting. Practicing molecular pathologists, clinical chemists, and toxicologists, as well as clinicians and researchers in training, will benefit from this book's clear presentation of protocols and theoretical framework. Includes over 200 easy-to-follow experimental protocols Features chapter-ending summaries of "Key Points to Remember" to bring beginners up to speed with any seasoned veteran in the field Offers two chapters written by industry leaders in the fields of in situ hybridization, immunohistochemistry, and computer software for co-expression analyses

Cawson S Essentials Of Oral Pathology And Oral Medicine E Book

Author : Roderick A. Cawson
ISBN : 9780702053719
Genre : Medical
File Size : 45. 94 MB
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Cawson's Essentials of Oral Pathology and Oral Medicine E-Book

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