life extension lessons from drosophila healthy ageing and longevity

Download Book Life Extension Lessons From Drosophila Healthy Ageing And Longevity in PDF format. You can Read Online Life Extension Lessons From Drosophila Healthy Ageing And Longevity here in PDF, EPUB, Mobi or Docx formats.

Life Extension

Author : Alexander Vaiserman
ISBN : 9783319183268
Genre : Medical
File Size : 41. 71 MB
Format : PDF, Kindle
Download : 347
Read : 607

Download Now


​This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in bio gerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecular and cellular processes that underlie aging process, and it can perhaps provide new therapeutic targets for the treatment of age-related disorders in humans. Drosophila models have been developed for a large variety of aging-related processes and diseases, and this book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process. Themes of health span, life extension and longevity-associated genes emerge in this collation of international research on Drosophila that is of relevance to geriatrics and gerontology, animal genetics and genomics, and biomedicine. This fascinating, illustrated book will be of interest to a wide audience, ranging from academic researchers to the general reader.

Epigenetics Of Aging And Longevity

Author : Alexey Moskalev
ISBN : 9780128110836
Genre : Medical
File Size : 42. 46 MB
Format : PDF, ePub, Docs
Download : 192
Read : 835

Download Now


Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan

Longevity Promotion Multidisciplinary Perspectives

Author : Ilia Stambler PhD
ISBN : 9781387164059
Genre : Science
File Size : 71. 41 MB
Format : PDF, Kindle
Download : 343
Read : 516

Download Now


This book considers the multidisciplinary aspects of longevity promotion, from the advocacy, historical, philosophical and scientific perspectives. The first part on longevity advocacy includes examples of pro-longevity campaigns, outreach materials, frequent debates and policy suggestions. The second part on longevity history includes historical analyses of life-extensionism as a social and intellectual movement. The third part on longevity philosophy surveys the aspirations and arguments for increasing healthy longevity in the philosophical and religious traditions of ancient Greece, India, the Middle East, in particular in Islam and Judaism, and the Christian tradition. Finally, the fourth part on longevity science includes brief discussions of some of the scientific issues in life extension research. These discussions are in no way exhaustive, but are intended to simulate additional interest, consultation and study of longevity science and its social and cultural implications.

Insect Epigenetics

Author :
ISBN : 9780128118344
Genre : Science
File Size : 52. 57 MB
Format : PDF, Mobi
Download : 728
Read : 451

Download Now


Insect Epigenetics, Volume 53 provides readers with the latest interdisciplinary reviews on the topic. Updated chapters in this new release include Epigenetics in insects: Mechanisms, ecological outcomes, and evolutionary consequences, Nutrition and epigenetic change in insects, microRNAs in Drosophila insulin regulation, Epigenetic regulation of longevity in insects, Epigenetic influences on diapause, the Impact of parasites on epigenetics of their insect hosts, The molecular physiology of locust swarming behavior, The future of environmental epigenetics: insights using the clonal water-flea model, and. Epigenetics – A hidden target of insecticides. Led by volume editor Heleen Verlinden, this is an essential reference source for entomologists, zoologists, geneticists and insect chemists. Presents a comprehensive overview of environmental impacts on insect epigenetics Written by leaders in their respective areas of research Ideal resource for entomologists, zoologists, geneticists and insect chemists

The Spatiotemporal Dynamics Of Longevity Defining Cellular Processes And Its Modulation By Genetic Dietary And Pharmacological Anti Aging Interventions

Author : Vladimir I. Titorenko
ISBN : 2889190900
Genre :
File Size : 88. 66 MB
Format : PDF, ePub, Docs
Download : 285
Read : 408

Download Now


Aging of multicellular and unicellular eukaryotic organisms is a highly complex biological phenomenon that affects a plethora of processes within cells. This wide array of longevity-defining cellular processes - which are governed by an evolutionarily conserved signaling network - includes oxidative metabolism and protein synthesis in mitochondria, lipid and carbohydrate metabolism, NAD+ homeostasis, amino acid biosynthesis and degradation, ammonium and amino acid uptake, ribosome biogenesis and translation, proteasomal protein degradation, nuclear DNA replication, chromatin assembly and maintenance, actin organization, apoptosis, necrosis, autophagy, protein folding, stress response, signal transduction, cell cycle, and cell growth. The focus of this Frontiers Special Topic Issue is on an important conceptual advance in our understanding of how cells integrate and control these numerous processes and how genetic, dietary and pharmacological anti-aging interventions extend longevity by altering their functional states and spatiotemporal dynamics. The Issue will highlight the various strategies used by evolutionarily diverse organisms for coordinating these longevity-defining cellular processes in space and time, critically evaluate the molecular and cellular mechanisms underlying such coordination, and outline the most important unanswered questions and directions for future research in this vibrant and rapidly evolving field.

Gerontology

Author : Kenneth F. Ferraro, PhD
ISBN : 9780826109668
Genre : Social Science
File Size : 58. 73 MB
Format : PDF
Download : 308
Read : 781

Download Now


This newest edition of a core graduate level textbook has added six new chapters to further enrich the ìgerontological imagination,î and encourage an interdisciplinary approach to the study of aging. Academically rigorous yet clear and accessible, the text provides the most current findings from leading gerontological researchers and practitioners. New and updated chapters examine biology, exercise science/nutrition, communication science, geriatric medicine and nursing, demography, anthropology, economics, human development, psychology, political science, sociology, social work, and law, to provide broadly drawn perspectives on the study of aging. Special emphasis is placed on current challenges regarding policy and service delivery in the face of fiscal uncertainty. Additionally, this new edition covers international outlooks on aging given the increasing influence of globalization on individual lives. By interweaving knowledge from a broad range of disciplines, Wilmoth and Ferraro have created a comprehensive picture of gerontology today that will enhance course instruction and provide a new window into the future of the discipline. New chapters address: Geriatric medicine and nursing Communication disorders and aging International and cross-cultural perspectives on aging Public policy and the needs of diverse aging populations Geriatric social work Legal perspectives on aging Key Features: Interweaves current gerontological research and ideas from multiple disciplines Addresses biology, psychology, human development, sociology, and economics as they relate to gerontology Presents additional disciplinary perspectives including exercise science/nutrition, communication science, geriatric medicine and nursing, demography, anthropology, political science, social work, and law. Includes Ferraroís classic chapter on ìThe Gerontological Imaginationî

The Future Of Aging

Author :
ISBN : 9789048139996
Genre : Medical
File Size : 30. 70 MB
Format : PDF, Mobi
Download : 114
Read : 627

Download Now


Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.

Pinsa B

Author : Indian National Science Academy
ISBN : UOM:39015057932934
Genre : Biology
File Size : 43. 29 MB
Format : PDF
Download : 726
Read : 313

Download Now



Proceedings Of The Indian National Science Academy

Author : Indian National Science Academy
ISBN : CHI:66269541
Genre : Biology
File Size : 85. 52 MB
Format : PDF, Mobi
Download : 998
Read : 1007

Download Now



Issues In Geriatric Medicine And Aging Research 2011 Edition

Author :
ISBN : 9781464964985
Genre : Medical
File Size : 38. 53 MB
Format : PDF, ePub, Docs
Download : 828
Read : 907

Download Now


Issues in Geriatric Medicine and Aging Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Geriatric Medicine and Aging Research. The editors have built Issues in Geriatric Medicine and Aging Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Geriatric Medicine and Aging Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Geriatric Medicine and Aging Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Top Download:

Best Books