lipidomics comprehensive mass spectrometry of lipids wiley series on mass spectrometry

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Author : Xianlin Han
ISBN : 9781119085287
Genre : Science
File Size : 54. 57 MB
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Covers the area of lipidomics from fundamentals and theory to applications Presents a balanced discussion of the fundamentals, theory, experimental methods and applications of lipidomics Covers different characterizations of lipids including Glycerophospholipids; Sphingolipids; Glycerolipids and Glycolipids; and Fatty Acids and Modified Fatty Acids Includes a section on quantification of Lipids in Lipidomics such as sample preparation; factors affecting accurate quantification; and data processing and interpretation Details applications of Lipidomics Tools including for Health and Disease; Plant Lipidomics; and Lipidomics on Cellular Membranes

Protein Carbonylation

Author : Joaquim Ros
ISBN : 9781119374961
Genre : Science
File Size : 30. 43 MB
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Protein carbonylation has attracted the interest of a great number of laboratories since the pioneering studies at the Earl Stadtman’s lab at NIH started in early 1980s. Since then, detecting protein carbonyls in oxidative stress situations became a highly efficient tool to uncover biomarkers of oxidative damage in normal and altered cell physiology. In this book, research groups from several areas of interest have contributed to update the knowledge regarding detection, analyses and identification of carbonylated proteins and the sites where these modifications occur. The scientific community will benefit from these reviews since they deal with specific, detailed technical approaches to study formation and detection of protein carbonyls. Moreover, the biological impact of such modifications in metabolic, physiologic and structural functions and, how these alterations can help understanding the downstream effects on cell function are discussed. Oxidative stress occurs in all living organisms and affects proteins and other macromolecules: Protein carbonylation is a measure of oxidative stress in biological systems Mass spectrometry, fluorescent labelling, antibody based detection, biotinylated protein selection and other methods for detecting protein carbonyls and modification sites in proteins are described Aging, neurodegenerative diseases, obstructive pulmonary diseases, malaria, cigarette smoke, adipose tissue and its relationship with protein carbonylation Direct oxidation, glycoxidation and modifications by lipid peroxidation products as protein carbonylation pathways Emerging methods for characterizing carbonylated protein networks and affected metabolic pathways

Mass Spectrometry And Stable Isotopes In Nutritional And Pediatric Research

Author : Henk Schierbeek
ISBN : 9781119341246
Genre : Science
File Size : 35. 37 MB
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A guide for scientists, pediatricians and students involved in metabolic studies in pediatric research Addresses the availability of modern analytical techniques and how to apply these techniques in metabolic studies Covers the whole range of available mass spectrometric techniques used for metabolic studies including Stable Isotope Methodology Presents the relevance of mass spectrometry and stable isotope methodology in pediatric research covering applications in Nutrition, Obesity, Metabolic Disorders, and Kidney Disorders Focuses on the interactions between nutrients and the endogenous metabolism within the body and how these factors affect the health of a growing infant

Interpretation Of Ms Ms Mass Spectra Of Drugs And Pesticides

Author : Wilfried M. A. Niessen
ISBN : 9781119294245
Genre : Science
File Size : 31. 26 MB
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Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

Chemical Analysis Of Non Antimicrobial Veterinary Drug Residues In Food

Author : Jack F. Kay
ISBN : 9781119325901
Genre : Science
File Size : 59. 4 MB
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Provides a single-source reference for readers interested in the development of analytical methods for analyzing non-antimicrobial veterinary drug residues in food Provides a comprehensive set of information in the area of consumer food safety and international trade Covers general issues related to analytical quality control and quality assurance, measurement uncertainty, screening and confirmatory methods Details many techniques including nanotechnology and aptamer based assays covering current and potential applications for non-antimicrobial veterinary drugs Provides guidance for analysis of banned drugs including natural and synthetic steroids, Resorcylic acid lactones, and Beta-agonists


Author : Herbert Budzikiewicz
ISBN : 9783527665884
Genre : Science
File Size : 76. 16 MB
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Die Massenspektrometrie, besonders in Kombination mit anderen Verfahren hat sich mittlerweile zu einer der wichtigsten Analysemethoden entwickelt, und zwar nicht nur in der Chemie, sondern auch in Nachbardisziplinen wie der Umweltanalytik, den Polymerwissenschaften, oder der Medizin. Die Neuauflage dieser bew?hrten Einf?hrung vermittelt den Nutzern die Grundlagen der Massenspektrometrie, tr?gt aber auch den rasanten Weiterentwicklungen der letzten Jahre Rechnung. Neben apparativen Neuentwicklungen auf dem Gebiet der Analysatoren sowie bei neuen Ionisationsmethoden werden auch inzwischen etablierte Methoden und neue Anwendungsfelder - Umwelt-, Doping-, Lebensmittel-, Proteomics- Analytik - anhand von ausgearbeiteten Beispielen erl?utert. Master-Studenten aller chemie-nahen Studieng?nge werden mit klarer Didaktik Grundlagen, aktuelle Techniken sowie neue Entwicklungen in der Massenspektrometrie vermittelt.


Author : Donald Armstrong
ISBN : STANFORD:36105131243250
Genre : Lipids
File Size : 46. 30 MB
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Metabolic Profiling Of Biologically Active Conjugated Dienes Using Diels Alder Derivatization And Electrospray Ionization Tandem Mass Spectrometry

Author : Pavel Andreevich Aronov
ISBN : UCAL:X78830
Genre :
File Size : 31. 20 MB
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Annual Plant Reviews Biology Of Plant Metabolomics

Author : Robert D. Hall
ISBN : 9781444339949
Genre : Science
File Size : 53. 63 MB
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Following a general introduction to the book, the first section of the book will include details of metabolomics of model species, including Arabidopsis, tomato and the legume Medicago. Chapters within the second section will consider the use and inter relationships of data integration, systems biology, genetics, genomics, metabolomics, chemometrics and biostatisitcs. The final section of the book will look at the use of metabolomics in food science, plant ecology, biodiversity and bioprocessing.Plant Metabolomicsis an essential purchase for plant scientists, plant geneticists and physiologists.

Handbuch Der Organischen Chemie

Author : F.K. Beilstein
ISBN : 9785885023368
Genre : Science
File Size : 53. 5 MB
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Pages 808-1586

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