marine biomedicine from beach to bedside

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Marine Biomedicine

Author : Bill J. Baker
ISBN : 9781466582132
Genre : Medical
File Size : 52. 19 MB
Format : PDF
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Marine Biomedicine: From Beach to Bedside assesses current efforts in marine biomedicine and evaluates the implications of recent advances on the future of the field. Richly illustrated in full color to enhance reader comprehension, the book covers four sections. The first one addresses the technology that has recently been brought to bear on the study of marine natural products, including omics and bioinformatic techniques. The second focuses on lead discovery and reviews various products and their biomedical potential. Examples of clinically successful marine products and discussions of approaches to the clinic are presented in the third section while the last section discusses prospects for the future of marine biodiscovery. Highlighting new technologies, this valuable resource provides an overview of both what is currently possible in the field as well as a detailed look at what is being done in marine natural products research.

Bioprospecting

Author : Russell Paterson
ISBN : 9783319479354
Genre : Science
File Size : 49. 54 MB
Format : PDF, Mobi
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This book considers all aspects of bioprospecting in 14 succinct chapters and a forward by David Hawksworth. The organisms addressed include plants, insects, fungi, bacteria and phages. Bioprospecting has never been more relevant and is of renewed interest, because of the extremely worrying rise in novel, resistant pathogenic microorganisms. The practices in pharmaceutical companies have failed to deliver novel antibiotics to control these infections. We need to look for new sources of drugs from the environment on a massive scale as drug discovery is “too important to fail”. Furthermore, the field can add great value to ecosystems in terms of economics, while providing additional reasons for maintaining associated services, such as food provision, benign climate, effective nutrient cycling and cultural practices. Bioprospecting provides another reason why climate change must be reduced in order to preserve relevant environments. Previous bioprospecting projects should be re-visited and established biodiversity centres have a major role. Many different ecosystems exist which contain unique organisms with the potential to supply novel antibiotics, enzymes, food, and cosmetics, or they may simply have aesthetic value. The book stresses the difficulties in obtaining successful products and yet describes why natural products should be investigated over combinatorial chemistry. Personal experience of bioprospecting projects are given significance. Issues such as how to share the benefits equitably with local communities are described and why pharmaceutical companies can be reluctant to be involved. Legal issues are discussed. Finally, there has never been a better time for a new book on bioprospecting, because of the need to preserve ecosystems, and from the emergence of resistant pathogenic microorganisms.

Chemical Biology Of Natural Products

Author : David J. Newman
ISBN : 9781351643283
Genre : Medical
File Size : 23. 57 MB
Format : PDF, Mobi
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Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.

Wilson And Walker S Principles And Techniques Of Biochemistry And Molecular Biology

Author : Andreas Hofmann
ISBN : 9781107162273
Genre : Medical
File Size : 34. 29 MB
Format : PDF
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A major update of a best-selling textbook that introduces students to the key experimental and analytical techniques underpinning life science research.

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