metallomics analytical techniques and speciation methods

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Metallomics

Author : Bernhard Michalke
ISBN : 9783527694914
Genre : Science
File Size : 33. 36 MB
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Latest developments, new insights and knowledge derived from speciation analysis in one unique compilation: The reader gets acquainted with relevant instrumental as well as application aspects of metallomics approaches, paving the road to understanding fate, pathway, and action of metals in environment and organisms. Upon an introductory chapter on analytical methods and strategies, the full bandwidth of applications is discussed. Expert chapter authors cast spotlights on recent topics such as metallomics applications to environmental and nutrition studies as well as biology and medicine. Special chapters deal with the impact of manganese and iron on neurodegeneration, and the impact of nanoparticles on health.

Metallomics

Author : Yasumitsu Ogra
ISBN : 9784431564638
Genre : Medical
File Size : 40. 18 MB
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This book focuses on recent topics in metallomics, a study of the metallome, or metal-containing biomolecules. Metals can induce various physiological and toxicological effects in a very small amounts, in other words, the concentrations of biometals are very low in organisms. Thus, analytical techniques for a trace amount of metal are crucial to understand the biological and toxicological functions of metals.This volume begins with an overview of metallomics including the history and development of the field. Subsequent parts provide basic and advanced techniques for metallomics. Speciation and imaging of metals are basic approaches to reveal the function of the metallome. The applications of speciation using an HPLC hyphenated with inductively coupled plasma mass spectrometry (LC-ICP-MS) and flow cytometry ICP-MS are described. As advanced approaches, the applications using a micro-flow injection-ICP-MS, an ICP-triple quadrupole mass spectrometer, an ICP-sector field mass spectrometer, and an ICP-multi-collector mass spectrometer are mentioned. For the imaging of metals, basic principles and applications of several techniques such as scanning X-ray fluorescence microscopy and ICP-MS equipped with laser ablation (LA-ICP-MS) are presented. Speciation analyses using electrospray ionization mass spectrometry (ESI-MS), X-ray Absorption Spectroscopy (XAS), and nuclear magnetic resonance spectroscopy (NMR) are also introduced. The last part highlights the medical and pharmaceutical applications of metallomics. Molecular biological approaches to reveal the effects of toxic metals, metal functions in brain and neurodegenerative diseases, and metallodrugs are explained. The topic of metal transporters is also presented.

Nuclear Analytical Techniques For Metallomics And Metalloproteomics

Author : Chunying Chen
ISBN : 9781847559012
Genre : Science
File Size : 80. 40 MB
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This authoritative book provides readers with a comprehensive view of advanced nuclear analytical techniques for metallomics and metalloproteomics.

Metallomics

Author : Marco Aurélio Zezzi Arruda
ISBN : 9783319901435
Genre : Science
File Size : 65. 11 MB
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This book covers the new Omics area, Metallomics. As Metallomics is intrinsically a transdisciplinary area, this book is authored by experts in the field on such diverse topics as Environmental, Nuclear, and Human Metallomics. Within these topics metals play important role, as being part of biomolecules, controlling different biochemical process, being signaling agents, being catalyst of biochemical reactions, among others. This volume demonstrates the importance of more investigation about metals and their interactions with biomolecules. As the knowledge in this field is growing and growing daily, then new challenges concerning studies involving Metallomics is appearing, such as comparative metallomics, speciation metallomics, real-time metallomics, new predictions of metals in biomolecules, metalloprotein databank expansion, interactions between metalloprotein-metalloprotein, among others.

Nuclear Analytical Techniques For Metallomics And Metalloproteomics

Author : Chunying Chen
ISBN : 9781847559012
Genre : Science
File Size : 73. 45 MB
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This authoritative book provides readers with a comprehensive view of advanced nuclear analytical techniques for metallomics and metalloproteomics.

Environmental Problems In Marine Biology

Author : Tamara Garcia Barrera
ISBN : 1482264501
Genre : Aquatic organisms
File Size : 29. 8 MB
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Marine environment can be affected by several pollutants such as the presence of elements and their chemical species, pharmaceuticals, nanoparticles and other emerging contaminants. Environmental monitoring can be assessed by genomics, proteomics (i.e. redox proteomics), chemical speciation analysis and metallomics, metabolomics as well as other advanced strategies. The present book is a useful methodological tool for researchers and specialists in the field of analytical chemistry, environmental sciences, biochemistry, genomics and toxicology. The book includes for the first time the methodological aspects and applications related to chemical speciation and �omics strategies applied to marine environment.

Microwave Assisted Sample Preparation For Trace Element Determination

Author : Erico Marlon Moraes Flores
ISBN : 9780444594440
Genre : Science
File Size : 40. 9 MB
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Microwave-Assisted Sample Preparation for Trace Element Analysis describes the principles, equipment, and applications involved in sample preparation with microwaves for trace element analysis. The book covers well-established applications as well as new trends in this field. Hot topics such as sample preparation for speciation, metabolomics, and halogen determination, as well as the alternatives of sample preparation for special samples (for example, carbon nanotubes, polymers, petroleum products), are also discussed. The use of microwaves in sample preparation has increased in recent decades. Several applications of microwaves for sample preparation can be found in the literature for practically all types of sample matrices, especially for the determination of trace elements by atomic spectrometric techniques, safely and cleanly reducing the time involved in this step. Microwave-assisted sample preparation is not only a tool for research but also for routine analysis laboratories; the state-of-the-art in sample preparation in trace element analysis. This book is the only resource for chemists specifically focused on this topic. The first book to describe the principles, equipment, and applications in microwave-assisted sample preparation Written by experts in the field who provide a comprehensive overview of the important concepts Introduces new alternatives and trends in microwave-assisted techniques

Analytical Techniques For Clinical Chemistry

Author : Sergio Caroli
ISBN : 9781118271841
Genre : Science
File Size : 58. 30 MB
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Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progress in instrumentation and applications in such fields as biomonitoring, diagnostics, food quality, biomarkers, pharmaceuticals, and forensics. Comprised of twenty-five chapters divided into three sections exploring Fundamentals, Selected Applications, and Future Trends, the book covers such critical topics as: Uncertainty in clinical chemistry measurements Metal toxicology in clinical, forensic, and chemical pathology Role of analytical chemistry in the safety of drug therapy Atomic spectrometric techniques for the analysis of clinical samples Biosensors for drug analysis Use of X-ray techniques in medical research Each chapter is written by one or more leading pioneers and experts in analytical chemistry. Contributions are based on a thorough review and analysis of the current literature as well as the authors' own firsthand experiences in the lab. References at the end of each chapter serve as a gateway to the literature, enabling readers to explore individual topics in greater depth. Presenting the latest achievements and challenges in the field, Analytical Techniques for Clinical Chemistry sets the foundation for future advances in laboratory research techniques.

Analysis Of Chemical Warfare Degradation Products

Author : Karolin K. Kroening
ISBN : 9781119993698
Genre : Science
File Size : 77. 81 MB
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This book describes nerve agents and vesicants, their decomposition and their degradation products' chemistry as well as their toxicity including a list of detection techniques of nerve agents and their degradation products. This book will present their history, toxicity, comparison between different sample preparation methods, separation techniques, and detection methods all together in a short, easy to read book, tied together by a single group doing the writing and the editing to assure smooth transition from chapter to chapter, with sufficient Tables and literature references for the reader who looks to further detail.The text will illustrate the pluses and minuses of the various techniques with sufficient references for the reader to obtain extensive detail.

The Evolution Of Meteorology

Author : Kevin Anthony Teague
ISBN : 9781119136156
Genre : Science
File Size : 87. 81 MB
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The essential guide to the history, current trends, and the future of meteorology This comprehensive review explores the evolution of the field of meteorology, from its infancy in 3000 bc, through the birth of fresh ideas and the naming of the field as a science, to the technology boom, to today. The Evolution of Meteorology reveals the full story of where meteorology was then to where it is now, where the field is heading, and what needs to be done to get the field to levels never before imagined. Authored by experts of the topic, this book includes information on forecasting technologies, organizations, governmental agencies, and world cooperative projects. The authors explore the ancient history of the first attempts to understand and predict weather and examine the influence of the very early birth of television, computers, and technologies that are useful to meteorology. This modern-day examination of meteorology is filled with compelling research, statistics, future paths, ideas, and suggestions. This vital resource: Examines current information on climate change and recent extreme weather events Starts with the Ancient Babylonians and ends with the largest global agreement of any kind with the Paris Agreement Includes current information on the most authoritative research in the field of meteorology Contains data on climate change theories and understanding, as well as extreme weather statistics and histories This enlightening text explores in full the history of the study of meteorology in order to bring awareness to the overall path and future prospects of meteorology.

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