metallomics analytical techniques and speciation methods

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Metallomics

Author : Bernhard Michalke
ISBN : 9783527339693
Genre : Science
File Size : 56. 23 MB
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Latest developments, new insights and knowledge derived from speciation analysis in one unique compilation: The reader gets acquainted with relevant instrumental as well as application aspects of metallomics approaches, paving the road to understanding fate, pathway, and action of metals in environment and organisms. Upon an introductory chapter on analytical methods and strategies, the full bandwidth of applications is discussed. Expert chapter authors cast spotlights on recent topics such as metallomics applications to environmental and nutrition studies as well as biology and medicine. Special chapters deal with the impact of manganese and iron on neurodegeneration, and the impact of nanoparticles on health.

Nuclear Analytical Techniques For Metallomics And Metalloproteomics

Author : Chunying Chen
ISBN : 9781847559012
Genre : Science
File Size : 42. 33 MB
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This authoritative book provides readers with a comprehensive view of advanced nuclear analytical techniques for metallomics and metalloproteomics.

Metallomics

Author : Yasumitsu Ogra
ISBN : 9784431564638
Genre : Medical
File Size : 40. 76 MB
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This book focuses on recent topics in metallomics, a study of the metallome, or metal-containing biomolecules. Metals can induce various physiological and toxicological effects in a very small amounts, in other words, the concentrations of biometals are very low in organisms. Thus, analytical techniques for a trace amount of metal are crucial to understand the biological and toxicological functions of metals.This volume begins with an overview of metallomics including the history and development of the field. Subsequent parts provide basic and advanced techniques for metallomics. Speciation and imaging of metals are basic approaches to reveal the function of the metallome. The applications of speciation using an HPLC hyphenated with inductively coupled plasma mass spectrometry (LC-ICP-MS) and flow cytometry ICP-MS are described. As advanced approaches, the applications using a micro-flow injection-ICP-MS, an ICP-triple quadrupole mass spectrometer, an ICP-sector field mass spectrometer, and an ICP-multi-collector mass spectrometer are mentioned. For the imaging of metals, basic principles and applications of several techniques such as scanning X-ray fluorescence microscopy and ICP-MS equipped with laser ablation (LA-ICP-MS) are presented. Speciation analyses using electrospray ionization mass spectrometry (ESI-MS), X-ray Absorption Spectroscopy (XAS), and nuclear magnetic resonance spectroscopy (NMR) are also introduced. The last part highlights the medical and pharmaceutical applications of metallomics. Molecular biological approaches to reveal the effects of toxic metals, metal functions in brain and neurodegenerative diseases, and metallodrugs are explained. The topic of metal transporters is also presented.

Metallomics

Author : Marco Aurélio Zezzi Arruda
ISBN : 9783319901435
Genre : Science
File Size : 26. 76 MB
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This book covers the new Omics area, Metallomics. As Metallomics is intrinsically a transdisciplinary area, this book is authored by experts in the field on such diverse topics as Environmental, Nuclear, and Human Metallomics. Within these topics metals play important role, as being part of biomolecules, controlling different biochemical process, being signaling agents, being catalyst of biochemical reactions, among others. This volume demonstrates the importance of more investigation about metals and their interactions with biomolecules. As the knowledge in this field is growing and growing daily, then new challenges concerning studies involving Metallomics is appearing, such as comparative metallomics, speciation metallomics, real-time metallomics, new predictions of metals in biomolecules, metalloprotein databank expansion, interactions between metalloprotein-metalloprotein, among others.

Nuclear Analytical Techniques For Metallomics And Metalloproteomics

Author : Chunying Chen
ISBN : 9781847559012
Genre : Science
File Size : 60. 51 MB
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This authoritative book provides readers with a comprehensive view of advanced nuclear analytical techniques for metallomics and metalloproteomics.

Oil And Gas Exploration

Author : Said Gaci
ISBN : 9781119227427
Genre : Science
File Size : 80. 54 MB
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Oil and Gas Exploration: Methods and Application presents a summary of new results related to oil and gas prospecting that are useful for theoreticians and practical professionals. The study of oil and gas complexes and intrusions occurring in sedimentary basins is crucial for identifying the location of oil and gas fields and for making accurate predictions on oil findings. Volume highlights include: Advanced geophysical techniques for achieving hydrocarbon exploration efficiency from beneath the Earth Discussion of theoretical and practical approaches in solving problems related to exploring and mining new oil and gas deposits New geological concepts for predicting potential hydrocarbon targets Novel methods of control of the outworking of these deposits using different geophysical methods, significant for optimization of mining hydrocarbon and carbonate deposits Estimation of the degree of outworking of oil and gas deposits, to facilitate the use of space-time monitoring of different kinds of fields Analysis of exploration data by an efficient processing system, based on strong methods proven mathematically Oil and Gas Exploration is a valuable resource for exploration geophysicists, petroleum engineers, geoengineers, petrologists, mining engineers, and economic geologists, who will gain insights into exploring new methods involved in finding natural resources from our Earth. Read an interview with the editors to find out more: https://eos.org/editors-vox/where-and-how-can-we-find-new-sources-of-oil-and-gas

Metalloproteomics

Author : Eugene Permyakov
ISBN : 0470447745
Genre : Science
File Size : 27. 23 MB
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Synthesizes the current knowledge in the field and provides new insights into medical applications Metalloproteomics is the large-scale study of metal-binding proteins. These proteins, which represent about one quarter of all the proteins in the Protein Data Bank, play important roles in all biological systems and all biological processes. Metalloproteomics provides the latest information on all major families of metal-binding proteins, including their structural, physico-chemical, and functional properties, enabling readers to better understand these proteins. Moreover, the book demonstrates how understanding the structures, properties, and functions of intracellular and extracellular metal-binding proteins may unlock the key to drug development for the treatment of a myriad of diseases. Written by Eugene Permyakov, an international expert and pioneer in the structural analysis of metal-binding proteins, the book offers Theoretical introduction to cation binding Broad range of methods for investigating the binding of different cations to proteins Characteristics of interactions of physiologically important cations of Ca, Mg, Zn, Fe, Mn, Co, Cu, Ni, Mo, W, Na, and K with proteins Detailed considerations of structural and physico-chemical properties of the metal-binding proteins Interactions of all other metal cations with proteins Interactions of different types of cations with nucleic acids Throughout the text, the author integrates principles of proteomics. In addition, detailed examples underscore the role metal-binding proteins play in health and medicine. Bringing together and analyzing all the latest findings, Metalloproteomics' scope and level of insight are unparalleled. It is recommended for biophysicists, biochemists, enzymologists, cell and molecular biologists, protein and peptide scientists, organic and bioinorganic chemists, and chemical biologists.

Microwave Assisted Sample Preparation For Trace Element Determination

Author : Erico Marlon Moraes Flores
ISBN : 9780444594440
Genre : Science
File Size : 35. 75 MB
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Microwave-Assisted Sample Preparation for Trace Element Analysis describes the principles, equipment, and applications involved in sample preparation with microwaves for trace element analysis. The book covers well-established applications as well as new trends in this field. Hot topics such as sample preparation for speciation, metabolomics, and halogen determination, as well as the alternatives of sample preparation for special samples (for example, carbon nanotubes, polymers, petroleum products), are also discussed. The use of microwaves in sample preparation has increased in recent decades. Several applications of microwaves for sample preparation can be found in the literature for practically all types of sample matrices, especially for the determination of trace elements by atomic spectrometric techniques, safely and cleanly reducing the time involved in this step. Microwave-assisted sample preparation is not only a tool for research but also for routine analysis laboratories; the state-of-the-art in sample preparation in trace element analysis. This book is the only resource for chemists specifically focused on this topic. The first book to describe the principles, equipment, and applications in microwave-assisted sample preparation Written by experts in the field who provide a comprehensive overview of the important concepts Introduces new alternatives and trends in microwave-assisted techniques

Analysis Of Chemical Warfare Degradation Products

Author : Karolin K. Kroening
ISBN : 9781119970194
Genre : Science
File Size : 20. 28 MB
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This book describes nerve agents and vesicants, their decomposition and their degradation products' chemistry as well as their toxicity including a list of detection techniques of nerve agents and their degradation products. This book will present their history, toxicity, comparison between different sample preparation methods, separation techniques, and detection methods all together in a short, easy to read book, tied together by a single group doing the writing and the editing to assure smooth transition from chapter to chapter, with sufficient Tables and literature references for the reader who looks to further detail.The text will illustrate the pluses and minuses of the various techniques with sufficient references for the reader to obtain extensive detail.

Analytical Techniques For Clinical Chemistry

Author : Sergio Caroli
ISBN : 9781118271841
Genre : Science
File Size : 77. 16 MB
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Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progress in instrumentation and applications in such fields as biomonitoring, diagnostics, food quality, biomarkers, pharmaceuticals, and forensics. Comprised of twenty-five chapters divided into three sections exploring Fundamentals, Selected Applications, and Future Trends, the book covers such critical topics as: Uncertainty in clinical chemistry measurements Metal toxicology in clinical, forensic, and chemical pathology Role of analytical chemistry in the safety of drug therapy Atomic spectrometric techniques for the analysis of clinical samples Biosensors for drug analysis Use of X-ray techniques in medical research Each chapter is written by one or more leading pioneers and experts in analytical chemistry. Contributions are based on a thorough review and analysis of the current literature as well as the authors' own firsthand experiences in the lab. References at the end of each chapter serve as a gateway to the literature, enabling readers to explore individual topics in greater depth. Presenting the latest achievements and challenges in the field, Analytical Techniques for Clinical Chemistry sets the foundation for future advances in laboratory research techniques.

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