molecular nutrition and diabetes a volume in the molecular nutrition series

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Molecular Nutrition And Diabetes

Author : Didac Mauricio
ISBN : 9780128017616
Genre : Medical
File Size : 28. 11 MB
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Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is a prelude to better nutritional control. Part One of the book provides general coverage of nutrition and diabetes in terms of dietary patterns, insulin resistance, and the glucose-insulin axis, while Part Two presents the molecular biology of diabetes and focuses on areas such as oxidative stress, mitochondrial function, insulin resistance, high-fat diets, nutriceuticals, and lipid accumulation. Final sections explore the genetic machinery behind diabetes and diabetic metabolism, including signaling pathways, gene expression, genome-wide association studies, and specific gene expression. While the main focus of each chapter is the basic and clinical research on diabetes as a nutritional problem, all chapters also end with a translational section on the implications for the nutritional control of diabetes. Offers updated information and a perspective on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of diabetes mellitus Explores how nutritional factors are involved in the pathogenesis of both type1 and type2 diabetes and their complications Investigates the molecular and genetic bases of diabetes and diabetic metabolism through the lens of a rapidly evolving field of molecular nutrition

Molecular Basis Of Nutrition And Aging

Author : Marco Malavolta
ISBN : 9780128018279
Genre : Medical
File Size : 25. 13 MB
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Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging Explores how nutritional factors are involved in the pathogenesis of aging across body systems Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition

The Molecular Nutrition Of Amino Acids And Proteins

Author : Dominique Dardevet
ISBN : 9780128023754
Genre : Health & Fitness
File Size : 82. 77 MB
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The Molecular Nutrition of Amino Acids and Proteins provides an in-depth look at the involvement and role of amino acids and proteins in molecular nutrition. Editor Dominique Dardevet has assembled a collection of chapters written by leading researchers and top professors that provide the reader with a comprehensive understanding of amino acids and proteins. The book provides an introduction to the fundamentals of amino acids and proteins as well as the composition of food. It then delves into the molecular biology of the cell and genetic machinery and its function. The Molecular Nutrition of Amino Acids and Proteins also features reference guides for terms and bullet-point summaries, making it readily accessible to novices while still providing the most up-to-date and detailed information that experienced researchers need. Provides a gentle introduction to the subject by first addressing nutritional information and then building in molecular aspects, clearly establishing fundamental information for the reader Facilitates reader comprehension by including succinct summary points in each chapter Contains a glossary of definitions that allows readers to easily reference terms Provides both a deep and broad understanding of the subject by containing overviews as well as detail-focused chapters

Molecular Aspects Of Alcohol And Nutrition

Author : Vinood B. Patel
ISBN : 9780128010037
Genre : Medical
File Size : 23. 97 MB
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Molecular Aspects of Alcohol and Nutrition is a valuable resource for nutrition researchers and nutritionists who study or treat alcohol-related diseases. Experts from across the field of alcohol research explain how alcohol disrupts normal fat, carbohydrate, and protein metabolic processes occurring in the liver as well as other parts of the body. The book discusses how this can lead to alcoholic liver disease (ALD) as well as contribute to the onset of Type 2 diabetes and the metabolic syndrome. It also explores how alcohol affects nutrient absorption in the gastrointestinal tract and can lead to anemia and reduced amounts of fat soluble vitamins. This book explores both the primary and secondary consequences of alcohol consumption. Chapters in the first section investigate the basic science of alcohol metabolism – focusing on how alcohol and its toxic metabolites disrupt and impair normal nutrient regulation at the molecular level. Further chapters explore how alcohol affects many extra-hepatic organs and tissues as well as the secondary consequences of alcohol consumption such as reduced levels of minerals like magnesium, calcium, and trace elements like zinc. Offers a valuable resource for nutrition researchers and nutritionists who study alcohol-related diseases and attempt to treat them through nutritional strategies Explores how alcohol and its toxic metabolite acetaldehyde disrupt and impair normal macro and micro nutrient regulation at the molecular level Investigates how alcohol affects and interferes with cell signaling, cell death pathways, calcium homeostasis leading to osteoporosis, oxygen balance, as well as the pathophysiology of alcohol consumption and abuse

Molecular And Cell Biology Of Type 2 Diabetes And Its Complications

Author : Francesco Belfiore
ISBN : 9783805566445
Genre : Medical
File Size : 23. 41 MB
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The present volume summarizes current research on type 2 diabetes, its etiology, pathogenesis and long-term vascular and neurological consequences, with special emphasis on molecular and biochemical mechanisms. Alterations in insulin secretion are comprehensively treated, focusing on the role of glucokinase as glucose sensor. Moreover, insulin action is analyzed with regard to both nonoxidative glucose utilization and glucose oxidation. Concerning the complications in chronic diabetes, topics covered include the effects of high glucose concentration on cellular and endothelial functions and on the glucose phosphorylation rate in non-insulin-sensitive tissues. Furthermore, the role of oxidative stress and advanced glycation end products as well as the significance of alterations in lipoprotein structure are considered. Finally, the pericyte loss in retinopathy and microalbuminuria as related to cardiovascular risk are discussed. Taken as a whole, the contributions included in this book represent a large body of information that will be of great interest to diabetologists, endocrinologists and internists interested in both the basic and clinical aspects of diabetes and its complications.

Molecular And Cellular Effects Of Nutrition On Disease Processes

Author : Grant Pierce
ISBN : 9781461557630
Genre : Science
File Size : 46. 27 MB
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Molecular Nutrition

Author : Jeffrey I. Mechanick
ISBN : 193670482X
Genre : Molecular biology
File Size : 51. 42 MB
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Molecular Basis Of Human Nutrition

Author : Tom Sanders
ISBN : 1420023225
Genre : Medical
File Size : 72. 7 MB
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Molecular Basis of Human Nutrition focuses on the metabolic basis of human nutrition, detailing recent knowledge and research in this field. It explains the biochemical functions of the essential nutrients and the physiological consequences of deficient and excessive intakes. These are described within the context of normal human diets and requirements for health. Although this book is about human nutrition, in some instances there are comparisons with and examples of other mammalian species to facilitate understanding of the principles. Molecular Basis of Human Nutrition is the only book to cover this particular subject and will prove very popular with both students and lecturers alike.

Gastrointestinal Tissue

Author : Jordi Gracia-Sancho
ISBN : 9780128093009
Genre : Medical
File Size : 48. 79 MB
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Gastrointestinal Tissue: Oxidative Stress and Dietary Antioxidants brings together leading experts from world renowned institutions, combining the basic mechanisms of gastrointestinal diseases with information regarding new and alternative treatments. The processes within the science of oxidative stress are described in concert with other processes, including apoptosis, cell signaling and receptor mediated responses, further recognizing that diseases are often multifactorial with oxidative stress as a component. By combining the critical molecular processes underlying free radical mediated pathologies and the role of dietary antioxidant molecules, a connection is made that helps advance therapies and the prevention of gastrointestinal pathological processes. This important reference is well designed with two complementary sections. Section One, Oxidative Stress and Gastroenterology, covers the basic processes of oxidative stress from molecular biology to whole organs, the gastrointestinal anatomy and sources of oxidative stress and free radicals and their products in gastrointestinal diseases. Section Two, Antioxidants and Gastroenterology covers antioxidants in foods, including plants and components. Covers the science of oxidative stress in gastrointestinal tissue and associated conditions and scenarios Provides information on optimal levels for human consumption of antioxidants, suggested requirements per day, recommended dietary allowances and curative/preventive effects of dietary antioxidants Presents an easy to reference guide with two complementary sections that discuss the pathophysiology of gastrointestinal diseases in relation to oxidative stress and antioxidant therapies

Diabesity

Author : Francine R. Kaufman, M.D.
ISBN : 0553900846
Genre : Health & Fitness
File Size : 49. 43 MB
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Experts now predict that more than one-third of American children born in 2000 will develop diabetes in their lifetime. Written by one of the world’s leading authorities on the link between obesity and diabetes, this passionate, frightening–but ultimately hopeful–book points the way to a solution. To enter Dr. Francine Kaufman’s clinic is to see the future of America: a 220-pound twelve-year-old boy…a 267-pound thirteen-year-old girl…their concerned but equally overweight parents…the human faces and human suffering behind the epidemic of type 2 diabetes that threatens to overwhelm our health care system. Once a disease of the elderly, type 2 diabetes now strikes adults in their prime–and, increasingly, children. It has nearly doubled in the last decade. The cause? Our soaring rates of obesity. Diabesity takes us to the front lines of the fight against this preventable but deadly disease. Through vivid patient stories, it explains how excess weight destroys the body’s ability to process sugar properly–with life-threatening consequences. It shows what happens when the genes that evolved to protect us from famine collide with a sedentary lifestyle that has put bacon cheeseburgers on every corner. And it demonstrates why our usual blame-the-victim response is futile in face of the complex, worldwide forces behind this epidemic. Detailing the tools for change at every level–from families to school systems to government–and reporting on innovative programs that are already making a difference, Diabesity offers a compelling action plan for winning this battle. From the Hardcover edition.

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