molecular photofitting predicting ancestry and phenotype using dna

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Molecular Photofitting

Author : Tony Frudakis, Ph.D.
ISBN : 0080551378
Genre : Social Science
File Size : 65. 21 MB
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In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects. Molecular Photofitting provides an accessible roadmap for both the forensic scientist hoping to make use of the new tests becoming available, and for the human genetic researcher working to discover the panels of markers that comprise these tests. By implementing population structure as a practical forensics and clinical genomics tool, Molecular Photofitting serves to redefine the way science and history look at ancestry and genetics, and shows how these tools can be used to maximize the efficacy of our criminal justice system. Explains how physical descriptions of individuals can be generated using only their DNA Contains case studies that show how this new forensic technology is used in practical application Includes over 100 diagrams, tables, and photos to illustrate and outline complex concepts

Fundamentals Of Forensic Dna Typing

Author : John M. Butler
ISBN : 0080961762
Genre : Law
File Size : 38. 20 MB
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Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Genetics And The Unsettled Past

Author : Keith Wailoo
ISBN : 9780813553368
Genre : Medical
File Size : 20. 38 MB
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Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to perform a kind of racially charged cultural work: to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present. Genetics and the Unsettled Past considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history. This unique collection brings together scholars from a wide range of disciplines—biology, history, cultural studies, law, medicine, anthropology, ethnic studies, sociology—to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, Native Americans, South Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.

Ancestors And Relatives

Author : Eviatar Zerubavel
ISBN : 9780199912315
Genre : Social Science
File Size : 61. 7 MB
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Genealogy has long been one of humanity's greatest obsessions. But with the rise of genetics, and increasing media attention to it through programs like Who Do You Think You Are? and Faces of America, we are now told that genetic markers can definitively tell us who we are and where we came from. The problem, writes Eviatar Zerubavel, is that biology does not provide us with the full picture. After all, he asks, why do we consider Barack Obama black even though his mother was white? Why did the Nazis believe that unions of Germans and Jews would produce Jews rather than Germans? In this provocative book, he offers a fresh understanding of relatedness, showing that its social logic sometimes overrides the biological reality it supposedly reflects. In fact, rather than just biological facts, social traditions of remembering and classifying shape the way we trace our ancestors, identify our relatives, and delineate families, ethnic groups, nations, and species. Furthermore, genealogies are more than mere records of history. Drawing on a wide range of evidence, Zerubavel introduces such concepts as braiding, clipping, pasting, lumping, splitting, stretching, and pruning to shed light on how we manipulate genealogies to accommodate personal and collective agendas of inclusion and exclusion. Rather than simply find out who our ancestors were and identify our relatives, we actually construct the genealogical narratives that make them our ancestors and relatives. An eye-opening re-examination of our very notion of relatedness, Ancestors and Relatives offers a new way of understanding family, ethnicity, nationhood, race, and humanity.

Genetic Justice

Author : Sheldon Krimsky
ISBN : 9780231145206
Genre : Law
File Size : 62. 93 MB
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Explores how different countries balance the use of DNA databanks in criminal justice with the rights of their citizens, including arguments about the dangers of collecting DNA from arrested individuals and the myth behind DNA profiling.

Race And The Genetic Revolution

Author : Sheldon Krimsky
ISBN : 9780231527699
Genre : Science
File Size : 51. 99 MB
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Do advances in genomic biology create a scientific rationale for long-discredited racial categories? Leading scholars in law, medicine, biology, sociology, history, anthropology, and psychology examine the impact of modern genetics on the concept of race. Contributors trace the interplay between genetics and race in forensic DNA databanks, the biology of intelligence, DNA ancestry markers, and racialized medicine. Each essay explores commonly held and unexamined assumptions and misperceptions about race in science and popular culture. This collection begins with the historical origins and current uses of the concept of "race" in science. It follows with an analysis of the role of race in DNA databanks and racial disparities in the criminal justice system. Essays then consider the rise of recreational genetics in the form of for-profit testing of genetic ancestry and the introduction of racialized medicine, specifically through an FDA-approved heart drug called BiDil, marketed to African American men. Concluding sections discuss the contradictions between our scientific and cultural understandings of race and the continuing significance of race in educational and criminal justice policy.

A Genetic Assay For Estimating Scalp Hair Pigmentation From Forensic Specimens

Author : Sara Lynn Jubelirer
ISBN : MSU:31293030635522
Genre : DNA
File Size : 46. 9 MB
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