negative affective states and cognitive impairments in nicotine dependence

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Negative Affective States And Cognitive Impairments In Nicotine Dependence

Author : F. Scott Hall
ISBN : 9780128026694
Genre : Medical
File Size : 70. 73 MB
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Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions. The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function. Provides a unique perspective on nicotine dependence that emphasizes negative reinforcement rather than positive reinforcement Examines psychiatric comorbidities and alleviation of withdrawal states as motivation for continued tobacco use Includes both clinical and preclinical perspectives Includes genetic and multi-neurotransmitter perspectives on nicotine use and withdrawal Emphasizes heterogeneity of underlying reasons for smoking, the need for multiple animal models to understand this heterogeneity, and the expectation of heterogeneous responses to potential treatments, underscoring the need for personalized therapeutics

Neural Mechanisms Of Addiction

Author : Mary Torregrossa
ISBN : 9780128123317
Genre : Medical
File Size : 46. 85 MB
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Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. Transcends multiple neural, neurochemical and behavioral domains Summarizes advances in the field of addiction research since the advent of optogenetics Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms

Biomarkers In Psychiatry

Author : Judith Pratt
ISBN : 9783319996424
Genre :
File Size : 88. 29 MB
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Translational Neuropsychopharmacology

Author : Trevor W. Robbins
ISBN : 9783319339139
Genre : Medical
File Size : 90. 68 MB
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This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.

Neuropathology Of Drug Addictions And Substance Misuse Volume 1

Author : Victor R. Preedy
ISBN : 9780128003763
Genre : Science
File Size : 90. 82 MB
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Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader’s knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body

Mindfulness Related Treatments And Addiction Recovery

Author : Marianne Marcus
ISBN : 9781135757038
Genre : Social Science
File Size : 55. 55 MB
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While mindfulness meditation has been used in clinical settings as an adjunctive treatment for substance use disorders for some time, there has been limited empirical evidence to support this practice. Mindfulness-Related Treatments and Addiction Recovery bridges this gap by reporting the findings of studies in which mindfulness practice has been combined with other behavioural treatments and/or adapted to meet the needs of a variety of client populations in recovery. Therapies used as interventions in the described studies include Mindfulness-Based Stress Reduction (MBSR), Mindfulness-Based Cognitive Therapy (MBCT), Dialectical Behavior Therapy (DBT), Acceptance and Commitment Therapy (ACT), Mindfulness-Based Relapse Prevention (MBRP), and Mindfulness-Based Therapeutic Community (MBTC) treatment. The book offers a glimpse into the many ways in which mindfulness strategies have been applied to various facets of the recovery process including stress, craving, anxiety, and other relapse related factors. Preliminary evidence, while not conclusive, suggests that mindfulness-based therapies are effective, safe, satisfying to clients, and that an individual, at-home mindfulness practice can be potentially sustained over time, beyond the intervention duration. This book was originally published as a special issue of Substance Abuse.

Health Consequences Of Smoking

Author : C. Everett Koop, M.D.
ISBN : 0788123149
Genre : Health & Fitness
File Size : 41. 22 MB
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Examines the scientific evidence that cigarettes and other forms of tobacco are addicting. Concludes that processes that determine tobacco addiction are similar to those that determine addiction to other drugs such as heroin and cocaine. Tables and figures. Bibliography. Index.

Abeloff S Clinical Oncology E Book

Author : John E. Niederhuber
ISBN : 9781455728817
Genre : Medical
File Size : 68. 99 MB
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Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

Journal Of The National Cancer Institute

Author :
ISBN : MINN:30000010710014
Genre : Cancer
File Size : 71. 84 MB
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Adolescent Brain Development

Author : Ronald E. Dahl
ISBN : STANFORD:36105119423361
Genre : Medical
File Size : 90. 21 MB
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Adolescent development involves complex changes in neurobehavioral systems underpinning the control of emotion and behavior. The adolescent transition is often difficult - morbidity and mortality increase 300 per cent during adolescence with the majority of the serious health problems related to difficulties with the control of behavior and emotions (e.g., suicide, homicide, depression, alcohol, nicotine, and other substance abuse). A critical gap in advancing research is the general lack of basic knowledge about human brain development during puberty and adolescence. In recent years, however, there have been several areas of research progress, and what is critically needed is better integration across disciplines with a specific focus on the neurobehavioral changes during normal adolescent development that contribute to increased risk-taking and/or reward seeking.

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