new trends in genetic risk assessment

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New Trends In Genetic Risk Assessment

Author : G. Jolles
ISBN : 9781483265674
Genre : Social Science
File Size : 38. 88 MB
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New Trends in Genetic Risk Assessment is based on the Fifth International Round Table of the Rhône-Poulenc Santé Foundation, held in Nice 1987. The conference was an attempt to review the latest theories and mechanisms stipulated for the various aspects of genotoxicity; it was above all an open forum to discuss the new trends, the new tests, and the new battery of tests for assessing the genetic risk of chemicals and especially drugs. This volume is actually not a proceedings of the meeting but a monograph specially edited to report the reviews which were presented and the discussions which took place; it was designed to provide a better understanding of the knowledge obtained in the most recent years and to help in the practical choice of approaches or tests for the prediction of the various forms of genotoxicity. The main subjects of this review concern molecular analysis of mutagenesis, detection of DNA damage, gene mutation, clastogenesis, aneuploidy, and germ cells. Each theme is preceded by a short overview summarizing the state of the art and the contributions of each author. Finally, special attention was given to the personal views of some leading toxicologists as to the battery of tests presently available or recommended.

Risk Assessment And Decision Making Using Test Results

Author : V. Chankong
ISBN : 9781468455953
Genre : Science
File Size : 21. 37 MB
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The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields engineering, epidemiology, chemistry, etc. These difficulties are particularly common in problems that have dynamic and stochastic characteristics driven by multiple purposes and goals, with complex interconnections and inter dependencies. Acquiring an appropriate data base, processing and analyzing model results, and transmitting these results at an appropriate technical, social, political, and institutional level are additional difficulties that must be addressed. This book is grounded on the premise that risks are best assessed on the basis of experimental results and sound mathematical analyses, coupled with the knowledge of experts. The carcinogenicity prediction and battery selection (ePBS) approach described herein provides a systematic mechan ism-a synthesis of systems and statistical and decision analyses-to aid researchers and decision makers in the critical field of carcinogenicity prediction in selecting an appropriate battery of tests to use and in translating experimental results into information that can be used as an aid to decision making.

Genetic Erosion And Pollution Assessment Methodologies

Author :
ISBN : 9789290437109
Genre : Plant diversity
File Size : 41. 20 MB
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New Trends In Brain Research

Author : F. J. Chen
ISBN : 159454834X
Genre : Medical
File Size : 60. 58 MB
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The brain is omnipresent in bodily functions. Its vast array of responsibilities includes the regulation of all physical movements, memory, learning and emotions, as well as the reception and interpretation of all sensory inputs. These numerous responsibilities require the facility of a very complex organ, and the brain is complex, to say the least. The brain's complexity provides a constant challenge for scientists to explore new theories. Because of the brain's wide-ranging role in bodily functions these studies have an impact on many other realms of science, such as psychology, neurology, and genetics. This book features recent studies from this important field of scientific research.

Methods For Risk Assessment Of Transgenic Plants

Author : Klaus Ammann
ISBN : 9783034880336
Genre : Science
File Size : 38. 41 MB
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For centuries, TK has been used almost exclusively by its creators, that is, indigenous and local communities. Access to, use of and handing down of TK has been regulated by local laws, customs and tmditions. Some TK has been freely accessible by all members of an indigenous or local community and has been freely exchanged with other communities; other TK has only been known to particular individuals within these communities such as shamans, and has been handed down only to particular individuals of thc next generation. Over many generations, indigenous and local communities have accumulated a great deal of TK which has generally been adapted, developed and improved by the generations that followed. For a long time, Western anthropologists and other scientists have generally been able to freely access TK and have documented it in their works. Still, this TK was only seldom used outside the indigenous and local communities that created it. More recently, however, Western scientists have become aware that TK is neither outdated nor valueless knowledge, but, instead, 1 can be useful to solve some of the problems facing today's world. Modem science, for example, has shown an increased interest in some fornls ofTK as knowledge that can be used in 4 research and development (R&D) activities and be integrated in modem innovations. This holds especially true for TK regarding genetic resources, which has been integrated in modem 6 phannaceuticals,s agro-chemicals and seed.

Handbook Of Breast Cancer Risk Assessment

Author : Victor G. Vogel
ISBN : 0763718602
Genre : Medical
File Size : 69. 73 MB
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This Essential Book Provides On-The-Spot Clinical Guidelines For Assessing And Advising Patients On Their Risk Of Breast Cancer, Therapeutic Options, And Other Issues Of Critical Importance To Women Concerned About Their Breast Health. In Highly-Condensed, Outline Format, The Handbook Provides Extensive, Authoritative, And Current Recommendations On Such Critical Issues As Hormone Replacement Therapy, Chemoprevention, Lifestyle Factors, Genetic Counseling, Imaging Of High-Risk Patients, Economic Factors, And Much More.

Human Gene Therapy Current Opportunities And Future Trends

Author : G. M. Rubanyi
ISBN : 3540004130
Genre : Medical
File Size : 70. 37 MB
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Advances in genetics, molecular biology and gene delivery technologies in recent years have led to new gene therapy strategies for treatment of a variety of diseases. This book gives a comprehensive overview of the present status and future directions of gene delivery systems and therapeutic strategies for the clinical application of gene therapy in cancer, cardiovascular and central nervous system diseases. Stem cell-based therapies and gene expression regulatory systems as novel platform technologies for various gene therapy applications are also discussed. Leading experts give excellent overviews of basic molecular aspects and clinical applications in this new emerging biomedical field.

Introgression From Genetically Modified Plants Into Wild Relatives

Author : Hans C. M. den Nijs
ISBN : 9780851998169
Genre : Science
File Size : 76. 77 MB
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Hybridization, transgene, crop, gene flow, resistant.

Clinical Genetics In Nursing Practice

Author : Felissa R. Lashley, PhD, RN, FABMGG
ISBN : 0826123678
Genre : Medical
File Size : 71. 22 MB
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Designated a Doody's Core Title! The third edition of this award-winning text provides new and updated knowledge about genetics issues relevant to nursing practice. Read in sequence or used as a reference, this is a comprehensive overview of how genetics affetcs the care that nurses provide. In addition to a summary of basic human genetics and discussion of the Human Genome Project, this new edition includes the latest research findings and implications about inheritance, major genetic disorders (cytogenetics or chromosomal, inherited biochemical, and congenital anomalies), and genetics in twin studies. A consideration of the ethical impact of genetics on society and future generations, as well as information on assisted reproduction round out the overview. Includes over 100 illustrations and photos of specific genetic disorders; tables and figures on the distribution of disease; and an extensive appendix listing associations, organizations, and websites relevant to genetics.

Annual Review Of Nursing Research Volume 29

Author : Ginette A. Pepper, PhD, RN, FAAN
ISBN : 9780826157553
Genre : Medical
File Size : 78. 30 MB
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This landmark annual review has provided three decades of knowledge, insight, and research on topics critical to the continued advancement of the nursing profession. This latest edition is a compilation of the most significant nursing research in genetics and genomics. Articles have been carefully selected by the editors, highly respected scholars and researchers in the field of genetics, to bring together current research that has particular relevance for translation into a clinical setting or expansion into other research areas. The review provides authoritative information of the highest caliber not only to researchers, but also to clinicians and undergraduate and graduate nursing students. Key Topics: The current status of genomic molecular science Ethical, legal, and social issues in genomics Genetics of diseases and symptoms Genomics across the lifespan

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