nonlinear mixture models a bayesian approach

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Nonlinear Mixture Models

Author : Tatiana Tatarinova
ISBN : 9781783266272
Genre : Mathematics
File Size : 29. 33 MB
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This book, written by two mathematicians from the University of Southern California, provides a broad introduction to the important subject of nonlinear mixture models from a Bayesian perspective. It contains background material, a brief description of Markov chain theory, as well as novel algorithms and their applications. It is self-contained and unified in presentation, which makes it ideal for use as an advanced textbook by graduate students and as a reference for independent researchers. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary background material needed to go further into the subject and explore the research literature. In this book the authors present Bayesian methods of analysis for nonlinear, hierarchical mixture models, with a finite, but possibly unknown, number of components. These methods are then applied to various problems including population pharmacokinetics and gene expression analysis. In population pharmacokinetics, the nonlinear mixture model, based on previous clinical data, becomes the prior distribution for individual therapy. For gene expression data, one application included in the book is to determine which genes should be associated with the same component of the mixture (also known as a clustering problem). The book also contains examples of computer programs written in BUGS. This is the first book of its kind to cover many of the topics in this field. Contents:IntroductionMathematical Description of Nonlinear Mixture ModelsLabel Switching and TrappingTreatment of Mixture Models with an Unknown Number of ComponentsApplications of BDMCMC, KLMCMC, and RPSNonparametric MethodsBayesian Clustering Methods Readership: Graduate students and researchers in bioinformatics, mathematical biology, probability and statistics, mathematical modeling, and pharmacokinetics. Keywords:Nonlinear Mixture Models;Bayesian Analysis;Monte Carlo Markov Chain

Finite Mixture And Markov Switching Models

Author : Sylvia Frühwirth-Schnatter
ISBN : 9780387357683
Genre : Mathematics
File Size : 45. 12 MB
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The past decade has seen powerful new computational tools for modeling which combine a Bayesian approach with recent Monte simulation techniques based on Markov chains. This book is the first to offer a systematic presentation of the Bayesian perspective of finite mixture modelling. The book is designed to show finite mixture and Markov switching models are formulated, what structures they imply on the data, their potential uses, and how they are estimated. Presenting its concepts informally without sacrificing mathematical correctness, it will serve a wide readership including statisticians as well as biologists, economists, engineers, financial and market researchers.

Finite Mixture Models

Author : Geoffrey McLachlan
ISBN : 9780471654063
Genre : Mathematics
File Size : 43. 6 MB
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An up-to-date, comprehensive account of major issues in finite mixture modeling This volume provides an up-to-date account of the theory and applications of modeling via finite mixture distributions. With an emphasis on the applications of mixture models in both mainstream analysis and other areas such as unsupervised pattern recognition, speech recognition, and medical imaging, the book describes the formulations of the finite mixture approach, details its methodology, discusses aspects of its implementation, and illustrates its application in many common statistical contexts. Major issues discussed in this book include identifiability problems, actual fitting of finite mixtures through use of the EM algorithm, properties of the maximum likelihood estimators so obtained, assessment of the number of components to be used in the mixture, and the applicability of asymptotic theory in providing a basis for the solutions to some of these problems. The author also considers how the EM algorithm can be scaled to handle the fitting of mixture models to very large databases, as in data mining applications. This comprehensive, practical guide: * Provides more than 800 references-40% published since 1995 * Includes an appendix listing available mixture software * Links statistical literature with machine learning and pattern recognition literature * Contains more than 100 helpful graphs, charts, and tables Finite Mixture Models is an important resource for both applied and theoretical statisticians as well as for researchers in the many areas in which finite mixture models can be used to analyze data.

Flexible Regression And Smoothing

Author : Mikis D. Stasinopoulos
ISBN : 9781351980371
Genre : Mathematics
File Size : 49. 66 MB
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This book is about learning from data using the Generalized Additive Models for Location, Scale and Shape (GAMLSS). GAMLSS extends the Generalized Linear Models (GLMs) and Generalized Additive Models (GAMs) to accommodate large complex datasets, which are increasingly prevalent. GAMLSS allows any parametric distribution for the response variable and modelling all the parameters (location, scale and shape) of the distribution as linear or smooth functions of explanatory variables. This book provides a broad overview of GAMLSS methodology and how it is implemented in R. It includes a comprehensive collection of real data examples, integrated code, and figures to illustrate the methods, and is supplemented by a website with code, data and additional materials.

Mixed Models

Author : Eugene Demidenko
ISBN : 9781118091579
Genre : Mathematics
File Size : 39. 87 MB
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Mixed modeling is one of the most promising and exciting areas of statistical analysis, enabling the analysis of nontraditional, clustered data that may come in the form of shapes or images. This book provides in-depth mathematical coverage of mixed models' statistical properties and numerical algorithms, as well as applications such as the analysis of tumor regrowth, shape, and image. The new edition includes significant updating, over 300 exercises, stimulating chapter projects and model simulations, inclusion of R subroutines, and a revised text format. The target audience continues to be graduate students and researchers. An author-maintained web site is available with solutions to exercises and a compendium of relevant data sets.

Predictive Modeling Applications In Actuarial Science

Author : Edward W. Frees
ISBN : 9781107029873
Genre : Business & Economics
File Size : 40. 56 MB
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This book is for actuaries and financial analysts developing their expertise in statistics and who wish to become familiar with concrete examples of predictive modeling.

Predictive Modeling Applications In Actuarial Science Volume 1 Predictive Modeling Techniques

Author : Edward W. Frees
ISBN : 9781139992312
Genre : Business & Economics
File Size : 85. 34 MB
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Predictive modeling involves the use of data to forecast future events. It relies on capturing relationships between explanatory variables and the predicted variables from past occurrences and exploiting this to predict future outcomes. Forecasting future financial events is a core actuarial skill - actuaries routinely apply predictive-modeling techniques in insurance and other risk-management applications. This book is for actuaries and other financial analysts who are developing their expertise in statistics and wish to become familiar with concrete examples of predictive modeling. The book also addresses the needs of more seasoned practising analysts who would like an overview of advanced statistical topics that are particularly relevant in actuarial practice. Predictive Modeling Applications in Actuarial Science emphasizes lifelong learning by developing tools in an insurance context, providing the relevant actuarial applications, and introducing advanced statistical techniques that can be used by analysts to gain a competitive advantage in situations with complex data.

Mixed Effects Models In S And S Plus

Author : José C. Pinheiro
ISBN : 9781441903174
Genre : Computers
File Size : 76. 25 MB
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R, linear models, random, fixed, data, analysis, fit.

Bayesian Data Analysis Third Edition

Author : Andrew Gelman
ISBN : 9781439898208
Genre : Mathematics
File Size : 46. 87 MB
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Winner of the 2016 De Groot Prize from the International Society for Bayesian Analysis Now in its third edition, this classic book is widely considered the leading text on Bayesian methods, lauded for its accessible, practical approach to analyzing data and solving research problems. Bayesian Data Analysis, Third Edition continues to take an applied approach to analysis using up-to-date Bayesian methods. The authors—all leaders in the statistics community—introduce basic concepts from a data-analytic perspective before presenting advanced methods. Throughout the text, numerous worked examples drawn from real applications and research emphasize the use of Bayesian inference in practice. New to the Third Edition Four new chapters on nonparametric modeling Coverage of weakly informative priors and boundary-avoiding priors Updated discussion of cross-validation and predictive information criteria Improved convergence monitoring and effective sample size calculations for iterative simulation Presentations of Hamiltonian Monte Carlo, variational Bayes, and expectation propagation New and revised software code The book can be used in three different ways. For undergraduate students, it introduces Bayesian inference starting from first principles. For graduate students, the text presents effective current approaches to Bayesian modeling and computation in statistics and related fields. For researchers, it provides an assortment of Bayesian methods in applied statistics. Additional materials, including data sets used in the examples, solutions to selected exercises, and software instructions, are available on the book’s web page.

Latent Growth Curve Modeling

Author : Kristopher J. Preacher
ISBN : 9781412939553
Genre : Social Science
File Size : 48. 3 MB
Format : PDF
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Provides easy-to-follow, didactic examples of several common growth modeling approaches

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