pharmaceutical suspensions

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Pharmaceutical Suspensions

Author : Alok K. Kulshreshtha
ISBN : 1441910875
Genre : Medical
File Size : 81. 78 MB
Format : PDF
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The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.

Pharmaceutical Emulsions And Suspensions

Author : Françoise Nielloud
ISBN : 1420001515
Genre : Medical
File Size : 80. 54 MB
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Analyzes construction of experiments, focusing on variables, models, matrices, and reproducibility. This timely reference systematically examines the basic concepts and theoretical issues, methodologies for experiment and measurement, and practical health applications of emulsions and dispersions-describing formulation problems and identifying potential carriers for the delivery or targeting of new drugs. Evaluates anionic, cationic, and nonionic surfactants as dispersing, emulsifying, foaming, penetrating, and wetting agents. Written by more than 20 international researchers, Pharmaceutical Emulsions and Suspensions discusses uses of macroemulsions and (submicron) microemulsions illuminates delivery devices such as microparticles, nanospheres, liposomes, and mixed micelles investigates the application of self-emulsifying drug delivery systems (SEDDS) introduces techniques for increasing drug solubility with nanosuspensions addresses stabilization, flocculation, and coagulation problems in pharmaceutical and cosmetic suspensions surveys drug delivery by way of dermatological, follicular, and ocular routes explains the pharmacodynamics, bioavailability, and pharmacokinetics in the drug formulation development process compares and contrasts monomeric and micellar adsorption at oil-water interfaces and more! Containing over 1800 references, tables, equations, drawings, and micrographs, Pharmaceutical Emulsions and Suspensions is an ideal resource for pharmacists; physical, surface, colloid, cosmetic, food, and agricultural chemists; and upper-level undergraduate and graduate students in these disciplines.


Author : David B. Troy
ISBN : 0781746736
Genre : Medical
File Size : 70. 87 MB
Format : PDF
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For over 100 years, Remington has been the definitive textbook and reference on the science and practice of pharmacy. This Twenty-First Edition keeps pace with recent changes in the pharmacy curriculum and professional pharmacy practice. More than 95 new contributors and 5 new section editors provide fresh perspectives on the field. New chapters include pharmacogenomics, application of ethical principles to practice dilemmas, technology and automation, professional communication, medication errors, re-engineering pharmacy practice, management of special risk medicines, specialization in pharmacy practice, disease state management, emergency patient care, and wound care. Purchasers of this textbook are entitled to a new, fully indexed Bonus CD-ROM, affording instant access to the full content of Remington in a convenient and portable format.

Fasttrack Pharmaceutics Dosage Form And Design 2nd Edition

Author : David S. Jones
ISBN : 9780857110787
Genre : Medical
File Size : 76. 5 MB
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FASTtrack Pharmaceutics – Dosage Form and Design focuses on what you really need to know in order to pass your pharmacy exams. It provides concise, bulleted information, key points, tips and an all-important self-assessment section, including MCQs.

Applied Surfactants

Author : Tharwat F. Tadros
ISBN : 9783527604531
Genre : Science
File Size : 67. 47 MB
Format : PDF
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While currently available titles either focus on the basics or on very specific subtopics, this text meets the need for a comprehensive survey of surfactants and their properties, with a strong emphasis on applications and their correlation to the fundamentals. The author covers their classification, physical properties, phase behavior, adsorption, effects - such as wetting, spreading and adhesion - as well as industrial applications in personal care and cosmetics, pharmaceuticals, agrochemicals and food products. Professor Tadros is a well-known expert on the topic of surfactants, with much experience in colloid science. Here, he uses his industrial experience to close the gap between fundamentals of surfactants and their relevance and applications in practice.

Theory And Practice Of Physical Pharmacy E Book

Author : Gaurav Jain
ISBN : 9788131232651
Genre : Medical
File Size : 78. 7 MB
Format : PDF, Kindle
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A core subject in pharmaceutics, physical pharmacy is taught in the initial semesters of B. Pharm. The methodical knowledge of the subject is required, and is essential, to understand the principles pertaining to design and development of drug and drug products. Theory and Practice of Physical Pharmacy is unique as it fulfils the twin requirements of physical pharmacy students: the authentic text on theoretical concepts and its application including illustrative exercises in the form of practicals. Covers all the topics included in various existing syllabi of physical pharmacy Provides an integrated understanding of theory and practical applications associated with physicochemical concepts Explore the latest developments in the field of pharmaceutics Reviews the relevance of physicochemical principles in the design of dosage form Ensures proper recapitulation through sufficient end-of-chapter questions Provides valuable learning tool in the form of multiple choice questions Multiple choice questions section especially useful for GPAT aspirants

Pharmaceutical Practice E Book

Author : Arthur J. Winfield
ISBN : 9780702041877
Genre : Medical
File Size : 25. 78 MB
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This comprehensive book covers a wide range of subjects relevant to pharmacy practice, including communication skills, managing a business, quality assurance, dispensing, calculations, packaging, storage and labeling of medicines, sterilization, prescriptions, hospital-based services, techniques and treatments, adverse drug reactions, pharmacoeconomics, and medicines management. Features useful appendices on medical abbreviations, pharmaceutical Latin terms, weights and measures, and presentation skills. This is a core text for pharmacy practice and dispensing modules of the pharmacy curriculum Covers key exam material for essential review and test preparation Features a user-friendly design with clear headings, chapter summaries, helpful boxes, and key points Text restructured with 14 new or radically revised chapters. All text revised in light of current pharmaceutical practice. New design using two colours.

Rheology Of Pharmaceutical Suspensions

ISBN : UOM:39015032290275
Genre : Rheology
File Size : 50. 51 MB
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Pharmaceutical Compounding And Dispensing

Author : John F. Marriott
ISBN : 9780853699125
Genre : Medical
File Size : 30. 50 MB
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Pharmacists have been responsible for compounding medicines for centuries. Although most modern medicines are not compounded in a local pharmacy environment, there are still occasions when it is imperative that pharmacists have this knowledge. Pharmaceutical Compounding and Dispensing provides a comprehensive guide to producing extemporaneous formulations safely and effectively. The book covers three core sections: the history of compounding; pharmaceutical forms and their preparation; product formulae. This is a modern, detailed and practical guide to the theory and practice of extemporaneous compounding and dispensing. Fully revised and updated, this new edition will be an indispensable reference for pharmacy students and practicing pharmacists. Supplementary videos demonstrating various dispensing procedures can be viewed online.

Bentley S Textbook Of Pharmaceutics E Book

Author : Sanjay Kumar Jain
ISBN : 9788131232668
Genre : Medical
File Size : 90. 87 MB
Format : PDF
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This adaptation of Bentley's Textbook of Pharmaceutics follows the same goals as those of the previous edition, albeit in a new look. The content of the old edition has been updated and expanded and several new chapters, viz. Complexations, Stability Testing as per ICH Guidelines, Parenteral Formulations, New Drug Delivery Systems and Pilot Plant Manufacturing, have been included, with an intention to make the book more informative for the modern pharmacists. The book has six sections: Section I deals with the physicochemical principles. Two new chapters: Complexations and ICH Guidelines for Stability Testing, have been added to make it more informative. Section II conveys the information regarding pharmaceutical unit operations and processes. Section III describes the area of pharmaceutical practice. Extensive recent updates have been included in many chapters of this section. Two new chapters: Parenteral Formulations and New Drug Delivery Systems, have been added. Section IV contains radioactivity principles and applications. Section V deals with microbiology and animal products. Section VI contains the formulation and packaging aspects of pharmaceuticals. Pilot Plant Manufacturing concepts are added as a new chapter, which may be beneficial to readers to understand the art of designing of a plant from the pilot plant model.

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