placebo and pain from bench to bedside

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Placebo And Pain

Author : Luana Colloca
ISBN : 9780123979315
Genre : Science
File Size : 56. 26 MB
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The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain: “This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues. --Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School Contains historical aspects of the placebo effect Discusses biological and psychological mechanisms of placebo analgesic responses Reviews implications of the placebo effect for clinical research and pain management Includes methodological and ethical aspects of the placebo effect

Neuroscience Of Pain Stress And Emotion

Author : Magne Arve Flaten
ISBN : 9780128006665
Genre : Psychology
File Size : 88. 75 MB
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Neuroscience of Pain, Stress, and Emotion: Psychological and Clinical Implications presents updated research on stress, pain, and emotion, all key research areas within both basic and clinical neuroscience. Improved research understanding of their interaction is ultimately necessary if clinicians and those working in the field of psychosomatic medicine are to alleviate patient suffering. This volume offers broad coverage of that interaction, with chapters written by major researchers in the field. After reviewing the neuroscience of pain and stress, the contents go on to address the interaction between stress and chronic/acute pain, the role of different emotions in pain, neurobiological mechanisms mediating these various interactions, individual differences in both stress and pain, the role of patient expectations during treatment (placebo and nocebo responses), and how those relate to stress modulation. While there are books on the market which discuss pain, stress, and emotion separately, this volume is the first to tackle their nexus, thus appealing to both researchers and clinicians. Represents the only comprehensive reference detailing the link between pain, stress and emotion, covering the neuroscientific underpinnings, related psychological processes, and clinical implications Compiles, in one place, research which promises to improve the methodology of clinical trials and the use of knowledge of pain-stress-emotion effects in order to reduce patients’ suffering Provides comprehensive chapters authored by global leaders in the field, the broadest, most expert coverage available

Pain Assessment And Pharmacologic Management

Author : Chris Pasero
ISBN : 9780323082631
Genre : Medical
File Size : 71. 42 MB
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Pain Assessment and Pharmacologic Management, by highly renowned authors Chris Pasero and Margo McCaffery, is destined to become the definitive resource in pain management in adults. It provides numerous reproducible tables, boxes, and figures that can be used in clinical practice, and emphasizes the benefits of a multimodal analgesic approach throughout. In addition, Patient Medication Information forms for the most commonly used medications in each analgesic group can be copied and given to patients. This title is an excellent resource for nurses to become certified in pain management. Presents best practices and evidence-based guidelines for assessing and managing pain most effectively with the latest medications and drug regimens. Features detailed, step-by-step guidance on effective pain assessment to help nurses appropriately evaluate pain for each patient during routine assessments. Provides reproducible tables, boxes, and figures that can be used in clinical practice. Contains Patient Medication Information forms for the most commonly used medications in each analgesic group, to be copied and given to patients. Offers the authors' world-renowned expertise in five sections: Underlying Mechanisms of Pain and the Pathophysiology of Neuropathic Pain includes figures that clearly illustrate nociception and classification of pain by inferred pathology. Assessment includes tools to assess patients who can report their pain as well as those who are nonverbal, such as the cognitively impaired and critically ill patients. Several pain-rating scales are translated in over 20 languages. Nonnopioids includes indications for using acetaminophen or NSAIDs, and the prevention and treatment of adverse effects. Opioids includes guidelines for opioid drug selection and routes of administration, and the prevention and treatment of adverse effects. Adjuvant Analgesics presents different types of adjuvant analgesics for a variety of pain types, including persistent (chronic) pain, acute pain, neuropathic pain, and bone pain. Prevention and treatment of adverse effects is also covered. Includes helpful Appendices that provide website resources and suggestions for the use of opioid agreements and for incorporating pain documentation into the electronic medical record. Covers patients from young adults to frail older adults. Provides evidence-based, practical guidance on planning and implementing pain management in accordance with current TJC guidelines and best practices. Includes illustrations to clarify concepts and processes such as the mechanisms of action for pain medications. Features spiral binding to facilitate quick reference.

The Handbook Of Cannabis Therapeutics

Author : Ethan B. Russo
ISBN : 9781136752858
Genre : Health & Fitness
File Size : 22. 33 MB
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Learn the facts behind the pharmacology and pharmacokinetics of controversial cannabis therapeutics The Handbook of Cannabis Therapeutics: From Bench to Bedside sets aside the condemnation and hysteria of society’s view of cannabis to concentrate on the medically sound aspects of cannabis therapeutics. The world’s foremost experts provide a reasoned, thoroughly researched overview of the controversial subject of cannabis, from its history as a medicine through its latest therapeutic uses. The latest studies on the botany, history, biochemistry, pharmacology, toxicology, clinical use for various illnesses such as AIDS, epilepsy, and multiple sclerosis, and side effects of marijuana are all examined and discussed in depth. This comprehensive resource is a compendium of articles from the Journal of Cannabis Therapeutics—with additional contemporary commentary. It presents startling research that explores and supports the medicinal value of cannabis use and its derivatives as a valid therapeutic resource for pain and inflammation, for several illnesses less responsive to other therapies, and even for certain veterinary uses. Cannabinoids such as nabilone, THC, levonantradol, ajulemic acid, dexanabinal, and others are extensively described, with a review of new indications for cannabinoid pharmaceuticals. The book is carefully referenced to encourage your examination of previous studies and provides tables and figures to enhance understanding of information. The Handbook of Cannabis Therapeutics discusses: the uses of cannabis in Arabic, Greek, Roman, and early English medicines absorption rates pharmacokinetics pharmacodynamics separate extracts versus the use of cannabis in its entirety the therapeutic value of the endocannabinoid system cannabinoids and newborn feeding a comparison of smoking versus oral preparations clinical research data on eating cannabis therapeutic uses as appetite stimulant treatments in obstetrics and gynecology medicinal treatments used in Jamaica the use of cannabis in the treatment of multiple sclerosis the benefits versus the adverse side effects of cannabis use The Handbook of Cannabis Therapeutics is a reference work certain to become crucial to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public.

Botanical Medicine

Author : Raymond Cooper
ISBN : PSU:000067166275
Genre : Medical
File Size : 25. 87 MB
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"Based loosely on the workshop Clinical Pharmacognosy: Contribution of Pharmacognosy to Clinical Trials of Botanicals and Dietary Supplements, held at the American Society of Pharmacognosy (ASP) meeting in Portland, Maine"--P. [xi].

Textbook Of Neural Repair And Rehabilitation Volume 1 Neural Repair And Plasticity

Author : Michael Selzer
ISBN : 9781139915953
Genre : Medical
File Size : 85. 11 MB
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In two freestanding volumes, the Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. Revised throughout, bringing the book fully up to date, this volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal central nervous system, mechanisms of neuronal death, axonal regeneration, stem cell biology, and research strategies targeted at axon regeneration and neuron replacement. New chapters have been added covering pathophysiology and plasticity in cerebral palsy, stem cell therapies for brain disorders and neurotrophin repair of spinal cord damage, along with numerous others. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.

Gender Differences In Mood And Anxiety Disorders

Author : Ellen Leibenluft
ISBN : 0880489588
Genre : Medical
File Size : 45. 28 MB
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Gender Differences in Mood and Anxiety Disorders: From Bench to Bedside compiles the latest research on gender differences in mood and anxiety disorders. It examines studies investigating whether the presentation and course of illness differ by gender, including the symptom profile, the likelihood of relapse, and the chronicity of the illness.

Wolff S Headache And Other Head Pain

Author : Stephen D. Silberstein
ISBN : NWU:35558005594904
Genre : Medical
File Size : 48. 89 MB
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The 8th edition of Wolff's Headache and Other Head Pain remains the definitive reference text in the field. Our knowledge and understanding of headache and its management have changed significantly in the twenty-first century. A new international headache classification has been adopted; headache pathophysiology and genetics have advanced; and epidemiologic studies have burgeoned. We have greater insights into the diagnosis and treatment of the secondary headaches. New treatments are available for primary headache disorders, including migraine, cluster, and chronic daily headache, and our understanding and knowledge are increasing by means of ongoing trials. The 8th edition encompasses all of this new material, with all chapters updated and many new authors added.

Principles Of Analgesic Use In The Treatment Of Acute Pain And Cancer Pain

Author : APS (American Psychological Society)
ISBN : 0000555010
Genre : Medical
File Size : 44. 59 MB
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Translational Pain Research

Author : Lawrence Kruger
ISBN : 1439812098
Genre : Health & Fitness
File Size : 36. 76 MB
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One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes. Distinguished Team of International Contributors In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on: Nociceptor sensitization Muscle nociceptors and metabolite detection Visceral afferents in disease Innovative rodent model for bone cancer pain Highly specific receptor cloning Modular molecular mechanisms relevant to painful neuropathies This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences.

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