plasminogen related growth factors novartis foundation symposia

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Plasminogen Related Growth Factors

Author : Gregory Bock
ISBN : 0471974560
Genre : Medical
File Size : 56. 67 MB
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Plasminogen is the inactive precursor of the blood proteinase plasmin, the enzyme responsible for the dissolution of fibrin clots. It has been recognized for several years, however, that plasmin has a broad substrate specificity and can cleave a number of other proteins, including several components of the extracellular matrix. Specific cell surface receptors for the two major plasminogen activators exist on a number of cell types and probably play an important role in controlling plasminogen activation. The identification of plasminogen fragments that lack enzymic activity but affect cell growth and migration, and the discovery of the plasminogenrelated growth factors, has highlighted previously unsuspected links between blood coagulation and fibrinolysis on the one hand, and regulation of cell behaviour on the other. This book brings together these two lines of work and discusses two main areas: first, the evolutionary and structural relationship between plasminogen-related growth factors and second, the role of plasminogen activation in cell regulation. Chapters in the book deal specifically with the evolutionary and structural links between the clotting and fibrinolytic proteins and the plasminogenrelated growth factors; the role of individual domains for enzymic or receptor binding activity; general features of the receptors for plasminogen-related growth factors and signalling via these receptors; the role of plasmin and the plasminogen-activators in cell regulation and organogenesis; the role of plasminogen-related growth factors in development, in the regeneration of epithelial organs and in angiogenesis; and the role of these growth factors in cancer and in atherogenesis

Plasminogen Related Growth Factors

Author : CIBA Foundation Symposium
ISBN : 9780470515471
Genre : Science
File Size : 79. 27 MB
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A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic proteins and plasminogen-related growth factors is also comprehensively examined.

Klotho

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ISBN : 9780128052358
Genre : Science
File Size : 70. 26 MB
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Klotho is the latest edition of a series first published in 1943 on Vitamins and Hormones and the longest-running serial published by Academic Press. It provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic, with volumes focusing on a single molecule or on a disease that is related to vitamins or hormones that are interpreted broadly so that related substances, such as transmitters, cytokines, growth factors, and others can be reviewed. Contains contributions from experts in the field of vitamins and hormones Covers a vast array of subjects In-depth, current information at the molecular to clinical levels

Development Of The Vascular System

Author : CIBA Foundation Symposium
ISBN : 9780470718513
Genre : Science
File Size : 88. 40 MB
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Protein Degradation In Health And Disease

Author : CIBA Foundation Symposium
ISBN : 9780470718261
Genre : Science
File Size : 64. 54 MB
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Parvoviruses

Author : Jonathan Kerr
ISBN : 9780340811986
Genre : Medical
File Size : 41. 5 MB
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This comprehensive reference work brings together for the first time information on every aspect of the parvoviruses in a single volume. It presents the new system of parvovirus classification, as agreed by the International Committee for the Taxonomy of Viruses (ICTV), and includes cutting edge information on the virology, molecular and cellular biology, immunology and clinical manifestations of infection with each known and proposed member of the family Parvoviridae. The book also describes the rapidly expanding basic and clinical science which underpins gene therapy applications using helper-dependent and helper-independent parvoviruses. The respected editorial group has drawn together renowned contributors from around the world to produce what will undoubtedly become the standard reference on the subject. It is essential reading for clinical or research virologists and microbiologists, infectious disease specialists, and public health specialists and laboratories.

Protein Turnover

Author : CIBA Foundation Symposium
ISBN : 9780470717592
Genre : Science
File Size : 49. 51 MB
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Cellular Migration And Formation Of Neuronal Connections

Author :
ISBN : 9780123973474
Genre : Science
File Size : 80. 27 MB
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The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity.

Pharmacology Of Purine And Pyrimidine Receptors

Author : Kenneth A. Jacobson
ISBN : 9780123855268
Genre : Medical
File Size : 82. 75 MB
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This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development.

Books In Print 2004 2005

Author :
ISBN : 0835246477
Genre : Literature
File Size : 43. 36 MB
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