quantitative cardiac electrophysiology

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Quantitative Cardiac Electrophysiology

Author : David Rosenbaum
ISBN : 0824743865
Genre : Medical
File Size : 40. 6 MB
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Provides an in-depth study of the theoretical and engineering principles behind the methods and technologies used to solve problems in experimental and clinical cardiac electrophysiology. Each chapter gives an extensive description of the principles underlying a simple method or technology and illustrates how it can be applied to solve problems in basic research and the clinical environment.

Quantitative Coronary Arteriography

Author : Johan H. C. Reiber
ISBN : 9789401137263
Genre : Medical
File Size : 74. 22 MB
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In June 1989, a third conference concentrating on the progress in quantita tive coronary angiography and related techniques was held in Rotterdam, again very successful as the two preceding events in 1985 and 1987. Tech nical as well as clinical aspects of digital and digitized coronarography, morphometry, parametric imaging and functional quantification of the human coronary circulation were presented and discussed by prominent exponents of those groups who have been active in this particular field for many years. This book contains the chapters representing the lectures held by leading experts during the symposium that update the knowledge currently available, including most recent aspects in angioscopy and intravascular ultrasound imaging. It also includes a historical review on the development of angiogra phic techniques from the very early days on to our times given by one of the pioneers in heart catheterization and angiography, Dr. Kurt Amplatz. Those who had the chance to listen to his talk, will surely remember his impressive, humorous lecture as one of the highlights of this meeting.

Cardiac Electrophysiology Circulation And Transport

Author : S. Sideman
ISBN : 0792311450
Genre : Medical
File Size : 39. 72 MB
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The cardiac system represents one of the most exciting challenges to human ingenuity. Critical to our survival, it consists of a tantalizing array of interacting phenomena, from ionic microscopic transport, membrane channels and receptors through cellular metabolism, energy production to fiber mechanics, microcirculation, electrical activation to the global, clinically observed, function, which is measured by pressure, volume, coronary flow, heart rate, shape changes and responds to imposed loads and pharmaceutical challenges. It is a complex interdisciplinary system requiring the joint efforts of the life sciences, the exact sciences, engineering and technology to understand and control the pathologies involved. The Henry Goldberg Workshops were set up to address these challenges. Briefly, our goals are: 1. To foster interdisciplinary interaction between scientists from different areas of cardiology, identify missing links, and catalyze new questions. 2. To relate micro scale cellular phenomena to the global, clinically manifested cardiac function. 3. To relate conceptual modeling and quantitative analysis to experimental and clinical data. 4. To encourage international cooperation so as to disperse medical and technological know how and lead to better understanding of the cardiac system. Today we celebrate the 7th birthday of a dream come true; a dream to bring together the diversified expertise in the various fields of science, engineering and medicine, to relate to the numerous interactive parameters and disciplines involved in the performance of the heart.

Bioelectricity

Author : Robert Plonsey
ISBN : 9781475731521
Genre : Technology & Engineering
File Size : 51. 13 MB
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In the first edition of Bioelectricity, Plonsey and Barr provided an introduction to electrophysiology following a quantitative approach. In this second edition they address new discoveries in the field of ion channels. The text is an introduction to electrophysiology utilizing a quantitative approach. It describes the principles of electrical fields, using basic principles from science and engineering while taking the biological applications into consideration. The book thus provides an introduction to the quantitative description of underlying electrophysiology with illustrative application to cardiac electrophysiology and functional electrical stimulation. The book can be used as a bridge to more advanced texts, particularly those that stress a quantitative approach.

Cardiac Sodium Channel Disorders An Issue Of Cardiac Electrophysiology Clinics

Author : Hugues Abriel
ISBN : 9780323326414
Genre : Medical
File Size : 35. 44 MB
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The sodium channel, a ubiquitous member of the cardiac, neural, and muscular conduction systems, has been implicated in the pathogenesis of an array of human diseases. Mutations associated with the cardiac sodium channel are responsible for a wide spectrum of disorders. The cardiac sodium channel and associated disorders are comprehensively examined in this issues of the Cardiac Electrophysiology Clinics.

Clinical And Electrophysiologic Management Of Syncope An Issue Of Cardiac Electrophysiology Clinics

Author : Antonio Raviele
ISBN : 9780323260893
Genre : Medical
File Size : 42. 19 MB
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This issue of Cardiac Electrophysiology Clinics devoted to syncope a disorder that is associated with increased mortality. Internationally recognized experts discuss the many causes of syncope, helping the clinician to distinguish life-threatening etiologies from benign ones.

Cardiac Electrophysiology Methods And Models

Author : Daniel C. Sigg
ISBN : 1441966587
Genre : Medical
File Size : 85. 32 MB
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Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

Cardiac Electrophysiology From Cell To Bedside

Author : Douglas P. Zipes
ISBN : 9781455728565
Genre : Medical
File Size : 62. 84 MB
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Cardiac Electrophysiology: From Cell to Bedside puts the latest knowledge in this subspecialty at your fingertips, giving you a well-rounded, expert grasp of every cardiac electrophysiology issue that affects your patient management. Drs. Zipes, Jalife, and a host of other world leaders in cardiac electrophysiology use a comprehensive, multidisciplinary approach to guide you through all of the most recent cardiac drugs, techniques, and technologies. Get well-rounded, expert views of every cardiac electrophysiology issue that affects your patient management from preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world. Visually grasp and easily absorb complex concepts through an attractive full-color design featuring color photos, tables, flow charts, ECGs, and more! Integrate the latest scientific understanding of arrhythmias with the newest clinical applications, to select the right treatment and management options for each patient. Stay current on the latest advancements and developments with sweeping updates and 52 NEW chapters - written by many new authors - on some of the hottest cardiology topics, such as new technologies for the study of the molecular structure of ion channels, molecular genetics, and the development of new imaging, mapping and ablation techniques. Get expert advice from Dr. Douglas P. Zipes - a leading authority in electrophysiology and editor of Braunwald's Heart Disease and the Heart Rhythm Journal - and Dr. Jose Jalife - a world-renowned leader and researcher in basic and translational cardiac electrophysiology. Access the full text online at Expert Consult, including supplemental text, figures, tables, and video clips. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.

Frontiers Of Cardiac Electrophysiology

Author : M.B. Rosenbaum
ISBN : 9789400967816
Genre : Medical
File Size : 56. 47 MB
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The goal of this book is to provide an integrated overview of some intriguing problems of cardiac electrophysiology. Topics have been selected that encompass mainly aspects which have been a matter of concern and interest in our Department over the past few years. We requested from the authors not only that they provide information about their own investiga tions, but also that they integrate their results with those published by oth ers. Furthermore, we urged them to be speculative in their interpretations in order to encourage exploration of related areas of investigation. To this end, the authors have presented their ,contributions in sufficient detail so that the information may not only educate the reader but also encourage and chal lenge him. It is through the concept of total integration -from in vitro to in vivo, from animal to man, from the pure scientist to the clinician -that we hope to advance our understanding of cardiac electrophysiology. The book brings together scientific work in which important advances have been made in the seventies, and in which even more substantial pro gress is likely to be made in the present decade. The chapters have been written by investigators who are authorities in the relevant scientific field. No attempt at summarizing has been made as this may not seldom lead to oversimplification, a risk that we do not dare take. The table of contents and list of contributors are, in this regard, self-explanatory.

Analytical And Quantitative Cardiology

Author : S. Sideman
ISBN : 9781461559597
Genre : Science
File Size : 70. 99 MB
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The tenth Henry Goldberg Workshop is an excellent occasion to recall our goals and celebrate some of our humble achievements. Vision and love of our fellow man are combined here to: 1) Foster interdisciplinary interaction between leading world scientists and clinical cardiologists so as to identify missing knowledge and catalyze new research ideas; 2) relate basic microscale, molecular and subcellular phenomena to the global clinically manifested cardiac performance; 3) apply conceptual modelling and quantitative analysis to better explore, describe, and understand cardiac physiology; 4) interpret available clinical data and design new revealing experiments; and 5) enhance international cooperation in the endless search for the secrets of life and their implication on cardiac pathophysiology. The first Goldberg Workshop, held in Haifa, in 1984, explored the interaction of mechanics, electrical activation, perfusion and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects. The third Goldberg Workshop, held in the USA at Rutgers University, in 1986, highlighted the transformation of the microscale activation phenomena to macro scale activity and performance, relating electrophysiology, energy metabolism and cardiac mechanics. The fourth Goldberg Workshop continued the effort to elucidate the various parameters affecting cardiac performance, with emphasis on the ischemic heart. The fifth Workshop concentrated on the effect of the inhomogeneity of the cardiac muscle on its performance. The sixth Workshop highlighted new imaging techniques which allow insight into the local and global cardiac performance.

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