streptomyces in nature and medicine the antibiotic makers

Download Book Streptomyces In Nature And Medicine The Antibiotic Makers in PDF format. You can Read Online Streptomyces In Nature And Medicine The Antibiotic Makers here in PDF, EPUB, Mobi or Docx formats.

Streptomyces In Nature And Medicine

Author : David A. Hopwood
ISBN : 0199722285
Genre : Medical
File Size : 69. 54 MB
Format : PDF, ePub
Download : 259
Read : 407

Get This Book


This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth century, but remained a Cinderella group until, in the 1940s, they shot to prominence with the discovery of streptomycin, the first effective treatment for tuberculosis and only the second antibiotic, after penicillin, to become a medical marvel. There followed a massive effort over several decades to find further treatments for infectious diseases and cancer, tempered by the rise of antibiotic resistance consequent on antibiotic misuse and over-use. The book goes on to describe the discovery of gene exchange in the actinomycetes in the context of the rise of microbial genetics in the mid-20th century, leading to determination of the complete DNA sequence of a model member of the group at the turn of the millennium. There follow chapters in which the intricate molecular machinery that adapts the organisms metabolism and development to life in the soil, including antibiotic production, is illuminated by the DNA blueprint. Then come an up-to-the minute account of the use of genetic engineering to make novel, hybrid, antibiotics, and a topical description of techniques to learn the roles of the thousands of genes in a genome sequence, throwing a powerful light on the biology of the organisms and their harnessing for increasing antibiotic productivity. In the final chapter we return to the mycobacteria that cause tuberculosis and leprosy, the first actinomycetes to be discovered, and how methodology, in part derived from the study of the streptomycetes, is being applied to understand and control these still deadly pathogens.

Synthetic Biology

Author : Christopher Voigt
ISBN : 9780123850751
Genre : Medical
File Size : 24. 25 MB
Format : PDF
Download : 840
Read : 805

Get This Book


Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. Encompasses a variety of different approaches, methodologies and disciplines Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation

Encyclopedia Of Biotechnology In Agriculture And Food Print

Author : Dennis R. Heldman
ISBN : 9781351452472
Genre : Technology & Engineering
File Size : 89. 87 MB
Format : PDF, Mobi
Download : 203
Read : 415

Get This Book


The Encyclopedia of Biotechnology in Agriculture and Food provides users with unprecedented access to nearly 200 entries that cover the entire food system, describing the concepts and processes that are used in the production of raw agricultural materials and food product manufacturing. So that users can locate the information they need quickly without having to flip through pages and pages of content, the encyclopedia avoids unnecessary complication by presenting information in short, accessible overviews. Addresses Environmental Issues & Sustainability in the Context of 21st Century Challenges Edited by a respected team of biotechnology experts, this unrivaled resource includes descriptions and interpretations of molecular biology research, including topics on the science associated with the cloning of animals, the genetic modification of plants, and the enhanced quality of foods. It discusses current and future applications of molecular biology, with contributions on disease resistance in animals, drought-resistant plants, and improved health of consumers via nutritionally enhanced foods. Uses Illustrations to Communicate Essential Concepts & Visually Enhance the Text This one-of-a-kind periodical examines regulation associated with biotechnology applications—with specific attention to genetically modified organisms—regulation differences in various countries, and biotechnology’s impact on the evolution of new applications. The encyclopedia also looks at how biotechnology is covered in the media, as well as the biotechnology/environment interface and consumer acceptance of the products of biotechnology. Rounding out its solid coverage, the encyclopedia discusses the benefits and concerns about biotechnology in the context of risk assessment, food security, and genetic diversity. ALSO AVAILABLE ONLINE This Taylor & Francis encyclopedia is also available through online subscription, offering a variety of extra benefits for both researchers, students, and librarians, including: Citation tracking and alerts Active reference linking Saved searches and marked lists HTML and PDF format options For more information, visit Taylor & Francis Online or contact us to inquire about subscription options and print/online combination packages. US: (Tel) 1.888.318.2367 / (E-mail) [email protected] International: (Tel) +44 (0) 20 7017 6062 / (E-mail) [email protected] Dennis R. Heldman speaks about his work on the CRC Press YouTube Channel.

Vaccine

Author : Arthur Allen
ISBN : 0393059111
Genre : Medical
File Size : 74. 88 MB
Format : PDF, Mobi
Download : 821
Read : 577

Get This Book


A definitive history of vaccination ranges from Edward Jenner's 1796 creation of the world's first smallpox inoculation to the present day, looking at both the benefits of vaccination as well as the current controversy over their potential neurological side effects and the pharmaceutical companies' emphasis on treatment rather than prevention.

Antibiotics

Author : Christine Zuchora-Walske
ISBN : 9781624013720
Genre : Juvenile Nonfiction
File Size : 28. 8 MB
Format : PDF, ePub
Download : 935
Read : 795

Get This Book


Amazing medical breakthroughs are made every day. In the past decades, medical researchers have cured diseases that were once deadly and devised new methods to heal that were once unimaginable. This title follows the development of antibiotics, including premodern forerunners to antibiotics, groundbreaking discoveries and the doctors who made them, and where the science is heading in the future. Learn how antibiotics work and why scientists need to continually discover new drugs. Sidebars, full-color photos, a glossary, and well-placed graphs, charts, and maps, enhance this engaging title. Aligned to Common Core Standards and correlated to state standards. Essential Library is an imprint of ABDO Publishing Company.

Making Women S Medicine Masculine

Author : Monica H. Green
ISBN : 9780191607356
Genre : History
File Size : 66. 34 MB
Format : PDF, ePub, Mobi
Download : 383
Read : 728

Get This Book


Making Women's Medicine Masculine challenges the common belief that prior to the eighteenth century men were never involved in any aspect of women's healthcare in Europe. Using sources ranging from the writings of the famous twelfth-century female practitioner, Trota of Salerno, all the way to the great tomes of Renaissance male physicians, and covering both medicine and surgery, this study demonstrates that men slowly established more and more authority in diagnosing and prescribing treatments for women's gynaecological conditions (especially infertility) and even certain obstetrical conditions. Even if their 'hands-on' knowledge of women's bodies was limited by contemporary mores, men were able to establish their increasing authority in this and all branches of medicine due to their greater access to literacy and the knowledge contained in books, whether in Latin or the vernacular. As Monica Green shows, while works written in French, Dutch, English, and Italian were sometimes addressed to women, nevertheless even these were often re-appropriated by men, both by practitioners who treated women and by laymen interested to learn about the 'secrets' of generation. While early in the period women were considered to have authoritative knowledge on women's conditions (hence the widespread influence of the alleged authoress 'Trotula'), by the end of the period to be a woman was no longer an automatic qualification for either understanding or treating the conditions that most commonly afflicted the female sex - with implications of women's exclusion from production of knowledge on their own bodies extending to the present day.

Urban Environments And Wildlife Law

Author : Paul A. Rees
ISBN : 9781405150958
Genre : Technology & Engineering
File Size : 70. 21 MB
Format : PDF, Mobi
Download : 743
Read : 189

Get This Book


Today construction industry is being asked more and more to protect the quality of the countryside and to help enhance our natural environment. The industry is subject to a complex and wide-ranging regulatory framework; it now needs to understand its responsibilities and take them seriously. Paul Rees provides here an authoritative guide, outlining wildlife and nature conservation law in the UK - including our European and international commitments, and giving clear explanations to a potentially costly area of law in a style accessible to the non-legal market. This comprehensive manual offers information and guidance for building surveyors, environmental managers, engineers and planners on: - the legal and planning issues around biodiversity, nature conservation and construction - how ecosystems work and why certain species and habitats need protection - where to go for the relevant legislation and appropriate organisations for help and advice. UK and European case law demonstrates how the law has functioned in particular instances, and case studies illustrate how companies have adapted to fulfil their legal obligations. These are key features of the book and provide information on important legal precedents as well as demonstrating current industry best practice.

The Multiple Roles Of Antibiotics And Antibiotic Resistance In Nature

Author : Fiona Walsh
ISBN : 9782889195251
Genre :
File Size : 59. 69 MB
Format : PDF, ePub, Docs
Download : 494
Read : 966

Get This Book


Antibiotics and antibiotic resistance have most commonly been viewed in the context of human use and effects. However, both have co-existed in nature for millennia. Recently the roles of antibiotics and antibiotic resistance genes have started to be discussed in terms of functions other than bacterial inhibition and protection. This special topic will focus on both the traditional role of antibiotics as warfare mechanisms and their alternative roles and uses within nature such as antibiotics as signals or communication mechanisms, antibiotic selection at low concentrations, the non-specific role of resistance mechanisms in nature: e.g. efflux pumps, evolution of antibiotic resistance and the role of persisters in natural antibiotic resistance.

Mathematical Methods In Biology And Neurobiology

Author : Jürgen Jost
ISBN : 9781447163534
Genre : Mathematics
File Size : 35. 24 MB
Format : PDF, Mobi
Download : 403
Read : 528

Get This Book


Mathematical models can be used to meet many of the challenges and opportunities offered by modern biology. The description of biological phenomena requires a range of mathematical theories. This is the case particularly for the emerging field of systems biology. Mathematical Methods in Biology and Neurobiology introduces and develops these mathematical structures and methods in a systematic manner. It studies: • discrete structures and graph theory • stochastic processes • dynamical systems and partial differential equations • optimization and the calculus of variations. The biological applications range from molecular to evolutionary and ecological levels, for example: • cellular reaction kinetics and gene regulation • biological pattern formation and chemotaxis • the biophysics and dynamics of neurons • the coding of information in neuronal systems • phylogenetic tree reconstruction • branching processes and population genetics • optimal resource allocation • sexual recombination • the interaction of species. Written by one of the most experienced and successful authors of advanced mathematical textbooks, this book stands apart for the wide range of mathematical tools that are featured. It will be useful for graduate students and researchers in mathematics and physics that want a comprehensive overview and a working knowledge of the mathematical tools that can be applied in biology. It will also be useful for biologists with some mathematical background that want to learn more about the mathematical methods available to deal with biological structures and data.

Wiley Encyclopedia Of Chemical Biology

Author : Tadhg P. Begley
ISBN : 0471754773
Genre : Science
File Size : 83. 45 MB
Format : PDF, Docs
Download : 626
Read : 320

Get This Book



Top Download:

Best Books