the chemistry and biology of nitroxyl hno

Download Book The Chemistry And Biology Of Nitroxyl Hno in PDF format. You can Read Online The Chemistry And Biology Of Nitroxyl Hno here in PDF, EPUB, Mobi or Docx formats.

The Chemistry And Biology Of Nitroxyl Hno

Author : Fabio Doctorovich
ISBN : 9780128011645
Genre : Science
File Size : 70. 87 MB
Format : PDF, Mobi
Download : 319
Read : 433

Get This Book


The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia

Nitrosation Reactions And The Chemistry Of Nitric Oxide

Author : D.L.H. Williams
ISBN : 0080473601
Genre : Science
File Size : 64. 64 MB
Format : PDF, ePub, Docs
Download : 358
Read : 560

Get This Book


Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990. * Provides an update on previously published literature on nitric oxide chemistry * Contains chapters on reagents for nitrosation, nitrosation at nitrogen, aliphatic and aromatic carbon, oxygen, sulfur and metal centres * Looks at hot research topics such as synthesis, properties and reactions of s-nitrosothiols

The Smallest Biomolecules Diatomics And Their Interactions With Heme Proteins

Author : Abhik Ghosh
ISBN : 0080556329
Genre : Science
File Size : 79. 63 MB
Format : PDF, Mobi
Download : 806
Read : 646

Get This Book


This is not a book on NO biology, nor about hemoglobin, nor about heme-based sensors per se. Of course, it covers all these topics and more, but above all, it aims at providing a truly multidisciplinary perspective of heme-diatomic interactions. The overarching goal is to build bridges among disciplines, to bring about a meeting of minds. The contributors to this book hail from diverse university departments and disciplines – chemistry, biochemistry, molecular biology, microbiology, zoology, physics, medicine and surgery, bringing with them very different views of heme-diatomic interactions. The hope is that the juxtaposition of this diversity will lead to increased exchanges of ideas, approaches, and techniques across traditional disciplinary boundaries. The authors represent a veritable Who’s Who of heme protein research and include John Olson, Tom Spiro, Walter Zumft, F. Ann Walker, Teizo Kitagawa, W. Robert Scheidt, Pat Farmer, Marie-Alda Gilles-Gonzalez, and many other equally distinguished scientists. Extremely distinguished list of authors Multidisciplinary character – equally suitable for chemists and biochemists Covers the hottest topics in heme protein research: sensors, NO biology, new roles of hemoglobin, etc.

Nox Related Chemistry

Author :
ISBN : 9780128018378
Genre : Science
File Size : 46. 2 MB
Format : PDF, Mobi
Download : 357
Read : 1184

Get This Book


NOx Related Chemistry is a volume of a series that presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the field and serves as an indispensable reference to advanced researchers. Each volume contains an index, and each chapter is fully referenced. Best-qualified scientists write on their own recent results dealing with basic fundamentals of NO-chemistry, with an eye into biological and environmental issues Editors and authors are recognized scientists in the field Features comprehensive reviews on the latest developments An indispensable reference to advanced researchers

Biochemical Targets Of Nitroxyl Hno And The Inhibition Of Hydrogen Peroxide Metabolism

Author : Matthew Irick Jackson
ISBN : UCLA:L0100089903
Genre :
File Size : 29. 44 MB
Format : PDF, Mobi
Download : 484
Read : 806

Get This Book



Nitric Oxide

Author : Louis J. Ignarro
ISBN : 9780128043196
Genre : Science
File Size : 65. 43 MB
Format : PDF, ePub, Docs
Download : 635
Read : 785

Get This Book


Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. Includes perspectives from Jack Lancaster on the discovery of EDRF and nitric oxide Provides detailed coverage of the new gaseous signaling agents Features expanded coverage on the principles of biology, including nitric oxide synthases, nitrite and nitrate biology and pathobiology, and signaling mechanisms Incorporates expanded pathobiology coverage, including nitric oxide and cardiovascular function, obesity, diabetes, and erectile function/dysfunction

Redox Active Therapeutics

Author : Ines Batinic-Haberle
ISBN : 9783319307053
Genre : Science
File Size : 69. 24 MB
Format : PDF, Kindle
Download : 578
Read : 972

Get This Book


This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.

An Examination Of The Physiologically Relevant Chemistry Of Nitroxyl Hno

Author : Natalie Mikki Cook
ISBN : UCLA:L0087458626
Genre :
File Size : 30. 95 MB
Format : PDF, Mobi
Download : 248
Read : 224

Get This Book



Transition Metal Catalysis In Aerobic Alcohol Oxidation

Author : Francesca Cardona
ISBN : 9781782621652
Genre : Science
File Size : 44. 4 MB
Format : PDF, Docs
Download : 662
Read : 557

Get This Book


The oxidation of primary and secondary alcohols to the corresponding carbonyl compounds is of fundamental importance in organic synthesis, due to the wide use of these products as precursors and intermediates for many drugs, vitamins and fragrances. However, traditional oxidants are often toxic and release considerable amounts of by-products. As an alternative, oxygen is among the cheaper and less polluting stoichiometric oxidants, and the implementation of a transition metal-based catalyst in combination with oxygen represents an emerging alternative to the traditional procedures. This book aims to give an overview of the aerobic oxidation of alcohols catalyzed by transition metals, and covers the most important advances in the last fifteen years. Following an introductory chapter on homogeneous-, heterogeneous- and nano-catalysis, use of copper, ruthenium, palladium, gold, vanadium and iron are discussed in turn. The book concludes with a useful overview that includes representative experimental procedures. This book will provide a valuable reference to organic chemists and green chemists in academia and industry.

Nitric Oxide Research From Chemistry To Biology Epr Spectroscopy Of Nitrosylated Compounds

Author : Yann A. Henry
ISBN : 9781461311850
Genre : Science
File Size : 72. 6 MB
Format : PDF, ePub
Download : 415
Read : 562

Get This Book



Top Download:

Best Books