the cytokine handbook two volume set

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The Cytokine Handbook Two Volume Set

Author : Angus W. Thomson
ISBN : 0080518796
Genre : Medical
File Size : 85. 27 MB
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The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features * Covers all main cytokines and chemokines * Written by experts * Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters * Includes major emphasis on clinical applications * Extensively illustrated with tables and figures

Handbook Of Stem Cells Two Volume Set

Author : Robert Lanza
ISBN : 0080533736
Genre : Science
File Size : 28. 30 MB
Format : PDF
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New discoveries in the field of stem cell research have frequently appeared in the news and in scientific literature. Research in this area promises to lead to new therapies for cancer, heart disease, diabetes, and a wide variety of other diseases. This two-volume reference integrates this exciting area of biology, combining the prerequisites for a general understanding of adult and embryonic stem cells, the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations, as well as a presentation by the world's experts of what is currently known about each specific organ system. The editors of the Handbook of Stem Cells include: Robert Lanza, Helen Blau, John Gearhart, Brigid Hogan, Douglas Melton, Malcolm Moore, Roger Pedersen, E. Donnall Thomas, James Thomson, Catherine Verfaillie, Irving Weissman, and Michael West. The Editorial Board includes: W. French Anderson, Peter Andrews, Anthony Atala, Jose Cibelli, Giulio Cossu, Robert Edwards, Martin Evans, Elaine Fuchs, Margaret Fuller, Fred Gage, Richard Gardner, Margaret Goodell, Ronald Green, William Haseltine, Joseph Itskovitz-Eldor, Rudolf Jaenisch, Ihor Lemischka, Dame Anne McLaren, Richard Mulligan, Stuart Orkin, Martin Pera, Benjamin Reubinoff, Janet Rossant, Hans Scholer, Austin Smith, Evan Snyder, Davor Solter, Alan Trounson, and Leonard Zon. This comprehensive set should be a much-needed addition to the library of students and researchers alike. * Provides comprehensive coverage on this highly topical subject * Contains contributions by the foremost authorities and premiere names in the field of stem cell research * The accompanying CD-ROM includes over 250 color figures

The Metabolic Pathway Engineering Handbook Two Volume Set

Author : Christina Smolke
ISBN : 9781420005622
Genre : Science
File Size : 60. 16 MB
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Christina Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast, is regarded as one of the most brilliant minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metabolic pathway engineering. With a wealth of cutting edge research and analysis, this work also serves as an invaluable resource for those seeking to add their own contributions. Organized by topic, this 3000 page reference is available as two volumes that can be purchased individually or as a set. Fundamentals The first volume provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction models, the regulation of metabolic pathways, and genome scale and multiscale modeling tools. It also covers developing appropriate hosts for metabolic engineering including the use of Escherichia coli, yeast, Bacillus subtilis, Streptomyces, filamentous fungi, annd mammalian cells using cell culture. Tool and Applications The second volume delves into evolutionary tools, including those associated with gene expression for metabolic pathway engineering. It covers applications of emerging technologies, including research on genome-wide technologies, DNA and phenotypic microarrays, and proteomics tools for experimentally determining flux through pathways. It also evaluates emerging applications for producing fine chemicals, drugs, and alternative fuels.

Handbook Of Food Processing Two Volume Set

Author : Theodoros Varzakas
ISBN : 9781466582316
Genre : Technology & Engineering
File Size : 32. 63 MB
Format : PDF, Docs
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Authored by world experts, the Handbook of Food Processing, Two-Volume Set discusses the basic principles and applications of major commercial food processing technologies. The handbook discusses food preservation processes, including blanching, pasteurization, chilling, freezing, aseptic packaging, and non-thermal food processing. It describes common food engineering unit operations as well as preservation processes required to convert raw materials into final products. Also covered are topics surrounding food safety and quality. Highlights: Case study on the effect of blanching conditions on sulforaphane content in purple and roman cauliflower (brassica oleracea l. Var. Botrytis) Principles of thermal processing described along with thermal process calculations Case study on microwave preservation of fruit-based products: application to kiwifruit puree Principles and applications of Ohmic heating Advances in food additives and contaminants Use of edible films and coatings in fresh fruits and vegetables preservation Handling and management of raw materials of foods Sensory evaluation of foods Hygiene and food sanitation Case studies on the implementation of ISO22000, HACCP, and other management tools for the implementation of food safety–traceability Food waste management case studies from the food industry along with life cycle analysis This two-volume set brings together aspects of food preservation and food processing operations methods of the basic food manufacturing processes addressing the relevant food safety and quality issues. Taking an innovative approach, the editors combine coverage of food preservation methods, the equipment needed to carry them out, and food processing operations methods of basic food manufacturing processes. The set helps you keep up with diverse consumer demands and rapidly developing markets.

Handbook Of Cell Signaling Three Volume Set

Author : Ralph A. Bradshaw
ISBN : 9780080533575
Genre : Science
File Size : 56. 3 MB
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The Handbook of Cell Signaling is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The subject matter has been divided into five main parts (each of which is headed by a recognized expert in the field): * Initiation: Extracellular and Membrane Events * Transmission: Effectors and Cytosolic Events * Nuclear Responses: Gene Expression and Translation * Events in Intracellular Compartments * Cell-Cell and Cell-Matrix Interactions Covered in extensive detail, these areas will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Tabular and well-illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field! * Contains approximately 470 articles * Provides well-organized sections on each essential area in signaling * Includes discussion on everything from ligand/receptor interactions to organ/organism responses * Extremely user-friendly

The Cytokine Handbook

Author : Angus W. Thomson
ISBN : 0126896631
Genre : Medical
File Size : 62. 22 MB
Format : PDF, ePub, Docs
Download : 672
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The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features * Covers all main cytokines and chemokines * Written by experts * Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters * Includes major emphasis on clinical applications * Extensively illustrated with tables and figures

Inflammation 4 Volume Set

Author : Jean-Marc Cavaillon
ISBN : 9783527338993
Genre : HEALTH & FITNESS
File Size : 75. 91 MB
Format : PDF, ePub
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The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.

Handbook Of Stem Cells

Author : Anthony Atala
ISBN : 9780123859433
Genre : Science
File Size : 73. 61 MB
Format : PDF, ePub, Docs
Download : 436
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New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world’s experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system. Provides comprehensive coverage on this highly topical subject Contains contributions by the foremost authorities and premiere names in the field of stem cell research Companion website - http://booksite.elsevier.com/9780123859426/ - contains over 250 color figures in presentation format

Modern Tribology Handbook

Author : Bharat Bhushan
ISBN : 0849384036
Genre :
File Size : 88. 73 MB
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The Mif Handbook

Author : Richard Bucala
ISBN : 9789814462303
Genre : Medical
File Size : 62. 42 MB
Format : PDF, ePub
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The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science. Contents:MIF Structure and Mechanism of Action:MIF, MIF Alleles, and the Regulation of the Host Response (Richard Bucala)MIF and the Chemokine Axis (Sandra Kraemer, Christian Weber and Jürgen Bernhagen)CD74, the Natural Receptor for MIF, Regulates Cell Survival in Health and Disease (Idit Shachar, Maya Gordin, Sivan Cohen, Inbal Binsky, Ayelet Marom and Shirly Becker-Herman)Towards the MIF Interactome (Jörg Klug and Andreas Meinhardt)Structural Studies of Small Molecule Inhibitors of MIF (Yoonsang Cho and Elias J Lolis)Regulation of MIF Expression:Epigenetic Control of MIF Expression (Thierry Roger, Jérôme Lugrin, Xavier C Ding and Thierry Calandra)Regulation of MIF Gene Expression in the Lung (Lili Li and John Baugh)Hypoxic Adaptation Facilitated by MIF (Robert A Mitchell)Infectious and Inflammatory Diseases:MIF in Infectious Diseases (Marcelo Torres Bozza and Claudia Neto Paiva)Role of Macrophage Migration Inhibitory Factor (MIF) in Parasitic Diseases (Rashmi Tuladhar, Ran Dong, Sanjay Varikuti, John R David and Abhay R Satoskar)MIF and Pulmonary Disease (Gordon Cooke, Michelle E Armstrong, Helen Conroy and Seamas C Donnelly)The Role of MIF in Neurogenic Inflammation (Pedro L Vera and Katherine L Meyer-Siegler)MIF and Lower Urinary Tract Disorders (Anthony DeAngelis, Phillip P Smith and George A Kuchel)Neoplasia:MIF in the Pathogenesis of Urological Cancer (Katherine L Meyer-Siegler and Pedro L Vera)MIF in Ovarian Cancer: Detection and Treatment (Guy Nadel, Ayesha B Alvero and Gil Mor)The Role of MIF on Tumorigenicity of Embryonic Stem Cells (Yi Ren)Atherogenesis and Cardiovascular Disease:MIF in Atherosclerosis (Heidi Noels, Jürgen Bernhagen and Christian Weber)MIF in Cardiovascular Disease (Edward J Miller, Dake Qi, Ji Li and Lawrence H Young)Neurophysiology and Neuropathology:A Detrimental Role of MIF in Ischemic Brain Damage (Kate L Lambertsen and Tomas Deierborg)Association of MIF with Autism Spectrum Disorders (Ivana Kawikova, James F Leckman, Astrid Morer and Elena L Grigorenko) Readership: Basic scientists working in inflammation and immunity as well as cytokine biology; clinically oriented scientists in infectious diseases, clinical immunology, and rheumatology; pharmacologists; drug development groups. Keywords:Immunology;Cytokine;Inflammation;Immunopathology;Macrophase Migration Inhibitory FactorKey Features:A comprehensive and up-to-date handbook of the biology, biochemistry, and pathophysiology of MIFContributors are all leaders in their respective fields

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