the emergence of life from chemical origins to synthetic biology

Download Book The Emergence Of Life From Chemical Origins To Synthetic Biology in PDF format. You can Read Online The Emergence Of Life From Chemical Origins To Synthetic Biology here in PDF, EPUB, Mobi or Docx formats.

The Emergence Of Life

Author : Pier Luigi Luisi
ISBN : 9781107092396
Genre : Science
File Size : 69. 49 MB
Format : PDF, ePub, Docs
Download : 414
Read : 1147

Get This Book


This fully updated and expanded edition addresses the origins of biological and synthetic life from a systems biology perspective.

The Emergence Of Life

Author : Pier Luigi Luisi
ISBN : 9781139455640
Genre : Science
File Size : 22. 7 MB
Format : PDF, ePub
Download : 155
Read : 259

Get This Book


The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.

Chemical Evolution And The Origin Of Life

Author : Horst Rauchfuss
ISBN : 9783540788232
Genre : Nature
File Size : 22. 11 MB
Format : PDF, Kindle
Download : 174
Read : 338

Get This Book


How did life begin on the early Earth? We know that life today is driven by the universal laws of chemistry and physics. By applying these laws over the past ?fty years, en- mous progress has been made in understanding the molecular mechanisms that are the foundations of the living state. For instance, just a decade ago, the ?rst human genome was published, all three billion base pairs. Using X-ray diffraction data from crystals, we can see how an enzyme molecule or a photosynthetic reaction center steps through its catalytic function. We can even visualize a ribosome, central to all life, translate - netic information into a protein. And we are just beginning to understand how molecular interactions regulate thousands of simultaneous reactions that continuously occur even in the simplest forms of life. New words have appeared that give a sense of this wealth of knowledge: The genome, the proteome, the metabolome, the interactome. But we can’t be too smug. We must avoid the mistake of the physicist who, as the twentieth century began, stated con?dently that we knew all there was to know about physics, that science just needed to clean up a few dusty corners. Then came relativity, quantum theory, the Big Bang, and now dark matter, dark energy and string theory. Similarly in the life sciences, the more we learn, the better we understand how little we really know. There remains a vast landscape to explore, with great questions remaining.

Creating Life In The Lab

Author : Fazale Rana
ISBN : 1441214585
Genre : Religion
File Size : 46. 28 MB
Format : PDF, ePub, Docs
Download : 160
Read : 388

Get This Book


Each year brings to light new scientific discoveries that have the power to either test our faith or strengthen it--most recently the news that scientists have created artificial life forms in the laboratory. If humans can create life, what does that mean for the creation story found in Scripture? Biochemist and Christian apologist Fazale Rana, for one, isn't worried. In Creating Life in the Lab, he details the fascinating quest for synthetic life and argues convincingly that when scientists succeed in creating life in the lab, they will unwittingly undermine the evolutionary explanation for the origin of life, demonstrating instead that undirected chemical processes cannot produce a living entity.

The Minimal Cell

Author : Pier Luigi Luisi
ISBN : 9048199441
Genre : Medical
File Size : 90. 35 MB
Format : PDF, ePub, Mobi
Download : 791
Read : 808

Get This Book


In the last ten years there has been a considerable increase of interest on the notion of the minimal cell. With this term we usually mean a cell-like structure containing the minimal and sufficient number of components to be defined as alive, or at least capable of displaying some of the fundamental functions of a living cell. In fact, when we look at extant living cells we realize that thousands of molecules are organized spatially and functionally in order to realize what we call cellular life. This fact elicits the question whether such huge complexity is a necessary condition for life, or a simpler molecular system can also be defined as alive. Obviously, the concept of minimal cell encompasses entire families of cells, from totally synthetic cells, to semi-synthetic ones, to primitive cell models, to simple biomimetic cellular systems. Typically, in the experimental approach to the construction of minimal the main ingredient is the compartment. Lipid vesicles (liposomes) are used to host simple and complex molecular transformations, from single or multiple enzymic reactions, to polymerase chain reactions, to gene expression. Today this research is seen as part of the broader scenario of synthetic biology but it is rooted in origins of life studies, because the construction of a minimal cell might provide biophysical insights into the origins of primitive cells, and the emergence of life on earth. The volume provides an overview of physical, biochemical and functional studies on minimal cells, with emphasis to experimental approaches. 15 International experts report on their innovative contributions to the construction of minimal cells.

First Life

Author : David Deamer
ISBN : 9780520948952
Genre : Nature
File Size : 44. 83 MB
Format : PDF, ePub, Docs
Download : 740
Read : 1231

Get This Book


This pathbreaking book explores how life can begin, taking us from cosmic clouds of stardust, to volcanoes on Earth, to the modern chemistry laboratory. Seeking to understand life’s connection to the stars, David Deamer introduces astrobiology, a new scientific discipline that studies the origin and evolution of life on Earth and relates it to the birth and death of stars, planet formation, interfaces between minerals, water, and atmosphere, and the physics and chemistry of carbon compounds. Deamer argues that life began as systems of molecules that assembled into membrane-bound packages. These in turn provided an essential compartment in which more complex molecules assumed new functions required for the origin of life and the beginning of evolution. Deamer takes us from the vivid and unpromising chaos of the Earth four billion years ago up to the present and his own laboratory, where he contemplates the prospects for generating synthetic life. Engaging and accessible, First Life describes the scientific story of astrobiology while presenting a fascinating hypothesis to explain the origin of life.

Life S Origin

Author : J. William Schopf
ISBN : 0520233905
Genre : Science
File Size : 62. 49 MB
Format : PDF, ePub
Download : 618
Read : 916

Get This Book


This volume explores the historical and current theories about the origin of life, addressing in particular the three key puzzles of how and when life began on Earth and in what form.

The Origin And Nature Of Life On Earth

Author : Eric Smith
ISBN : 9781107121881
Genre : Science
File Size : 55. 85 MB
Format : PDF, Kindle
Download : 355
Read : 886

Get This Book


Uniting the foundations of physics and biology, this groundbreaking multidisciplinary and integrative book explores life as a planetary process.

The Origins Of Life

Author : D. W. Deamer
ISBN : 193611304X
Genre : Science
File Size : 78. 98 MB
Format : PDF, ePub
Download : 778
Read : 1188

Get This Book


Providing a comprehensive account of the environment of the early Earth and descriptions of how the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities, this book is an essential reference for those interested in the origin of life on Earth.

What Is Life

Author : Addy Pross
ISBN : 9780198784791
Genre :
File Size : 48. 58 MB
Format : PDF
Download : 346
Read : 1316

Get This Book


Seventy years ago, Erwin Schrodinger posed a profound question: 'What is life, and how did it emerge from non-life?' This problem has puzzled biologists and physical scientists ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged. This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

Top Download:

Best Books