the evolution and emergence of rna viruses oxford series in ecology and evolution

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The Evolution And Emergence Of Rna Viruses

Author : Edward C. Holmes
ISBN : 9780199211128
Genre : Medical
File Size : 22. 95 MB
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While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.

Origin And Evolution Of Viruses

Author : Esteban Domingo
ISBN : 0080564968
Genre : Science
File Size : 26. 93 MB
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New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. * NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution * UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups * SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

Quantitative Ecology And Evolutionary Biology

Author : Otso Ovaskainen
ISBN : 9780191024221
Genre : Science
File Size : 83. 74 MB
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This novel, interdisciplinary text achieves an integration of empirical data and theory with the aid of mathematical models and statistical methods. The emphasis throughout is on spatial ecology and evolution, especially on the interplay between environmental heterogeneity and biological processes. The book provides a coherent theme by interlinking the modelling approaches used for different subfields of spatial ecology: movement ecology, population ecology, community ecology, and genetics and evolutionary ecology (each being represented by a separate chapter). Each chapter starts by describing the concept of each modelling approach in its biological context, goes on to present the relevant mathematical models and statistical methods, and ends with a discussion of the benefits and limitations of each approach. The concepts and techniques discussed throughout the book are illustrated throughout with the help of empirical examples. This is an advanced text suitable for any biologist interested in the integration of empirical data and theory in spatial ecology/evolution through the use of quantitative/statistical methods and mathematical models. The book will also be of relevance and use as a textbook for graduate-level courses in spatial ecology, ecological modelling, theoretical ecology, and statistical ecology.

Natural Hybridization And Evolution

Author : Michael L. Arnold
ISBN : 9780195099751
Genre : Science
File Size : 64. 74 MB
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This study includes data from sources which support the paradigm of natural hybridization as an important evolutionary process. It presents evidence of a significant role for natural hybridization in furthering adaptive evolution and evolutionary diversification in both plants and animals.

Virus As Populations

Author : Esteban Domingo
ISBN : 9780128009949
Genre : Science
File Size : 59. 54 MB
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Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere. Features current views on the key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

Evolutionary Biomechanics

Author : Graham K. Taylor
ISBN : 9780198566380
Genre : Technology & Engineering
File Size : 60. 47 MB
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This title discusses the study of evolution through the analysis of biomechanical systems. Instead of reviewing the entire breadth of the biomechanical literature, a few key examples are explored in depth as vehicles for discussing fundamental concepts, analytical techniques, and evolutionary theory.

Evolution In Health And Disease

Author : Stephen C. Stearns
ISBN : 9780199207459
Genre : Medical
File Size : 79. 23 MB
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A fully revised edition of a volume written by the world's leading authorities on this subject. It discusses how the evolution of humans and their pathogens have generated important medical issues, covering both infectious and degenerative diseases. It presents important ideas that are not yet sufficiently appreciated in the medical community.

The Evolution Of Sibling Rivalry

Author : Douglas W. Mock
ISBN : 0198577443
Genre : Social Science
File Size : 83. 74 MB
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One of the main tenets of evolutionary biology is that organisms behave so as to maximize the number of their genes that will be passed on to future generations. Parents often produce more offspring than they can rear in case special opportunities or calamities occur. This frequently leads to deprivations and even death of some offspring. This book is about the evolutionary diversity, importance, and consequences of such squeezes. The authors, experts in their field, review the theory, field experiments, and natural history of sibling rivalry across a broad sweep of organisms, in a clear and accessible style that should appeal to both academics and natural historians.

Comparative Genomics

Author : Eric Tannier
ISBN : 9783642161810
Genre : Science
File Size : 58. 80 MB
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The complexity of genome evolution has given birth to exciting challenges for computational biologists. A various range of algorithmic, statistical, mathem- ical techniques to elucidate the histories of molecules are developed each year and many are presented at the RECOMB satellite workshop on Comparative Genomics. It is a place where scientists working on all aspects of comparative genomics can share ideas on the development of tools and their application to relevant questions. This volume contains the papers presented at RECOMB-CG 2010, held on October 9–11 in Ottawa. The ?eld is still ?ourishing as seen from the papers presented this year: many developments enrich the combinatorics of genome rearrangements, while gene order phylogenies are becoming more and more - curate, thanks to a mixing of combinatorial and statistical principles, associated with rapid and thoughtful heuristics. Several papers tend to re?ne the models of genome evolution, and more and more genomic events can be modeled, from single nucleotide substitutions in whole genome alignments to large structural mutations or horizontal gene transfers.

Energetic Food Webs

Author : John C. Moore
ISBN : 9780198566182
Genre : Mathematics
File Size : 61. 87 MB
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Food webs describe biological communities in terms of feeding interactions. This book integrates the latest work on community dynamics, ecosystems energetics, and stability to dispel categorisation of the field into separate subdiciplines of population, community, and ecosystem ecology.

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