the evolution of the immune system conservation and diversification

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The Evolution Of The Immune System

Author : Davide Malagoli
ISBN : 9780128020135
Genre : Medical
File Size : 47. 72 MB
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The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership

Advances In Comparative Immunology

Author : Edwin Lowell Cooper
ISBN : 9783319767680
Genre : SCIENCE
File Size : 89. 98 MB
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Origin And Evolution Of The Vertebrate Immune System

Author : L. Du Pasquier
ISBN : 9783642596742
Genre : Medical
File Size : 60. 16 MB
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The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.

Janeway Immunologie

Author : Kenneth Murphy
ISBN : 9783662560044
Genre : Medical
File Size : 25. 80 MB
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Jetzt wieder auf dem neuesten Stand: DIE Einführung in die Immunologie für Studierende der Biowissenschaften und der Medizin Der Janeway, das bewährte und viel gelobte Standardlehrbuch der Immunologie, liegt nun erneut in einer vollständig überarbeiteten und aktualisierten Fassung vor. Das Werk führt den Leser in gewohnter Souveränität durch alle Aspekte des Immunsystems – vom ersten Einsatz der angeborenen Immunität bis zur Erzeugung der adaptiven Immunantwort, von den vielfältigen klinischen Konsequenzen normaler und pathologischer immunologischer Reaktionen bis zur Evolution des Immunsystems. In der 9. Auflage sind unter anderem neue Erkenntnisse zur modularen Immunantwort, zur Klassenwechsel-Rekombination, zur Vielfalt der CD4-T-Zellen, zu Chemokin-Netzwerken, zur Umgehung der Immunabwehr durch Pathogene und zur Immuntherapie von Krebs integriert. Zahlreiche neue Abbildungen veranschaulichen die im Text erläuterten Prozesse und Konzepte. Der umfangreiche Anhang zu den Methoden der Immunologie ist um etliche neue Techniken erweitert worden. Zudem wurden die Verständnisfragen an den Kapitelenden komplett überarbeitet. Das in zahlreiche Sprachen übersetzte Werk besticht durch seine Aktualität, seine konzeptionelle Geschlossenheit und seine ansprechende Illustration. Es bleibt damit in diesem unverändert rasant fortschreitenden Fachgebiet ein hochaktueller und verlässlicher Begleiter. Stimmen zu früheren Auflagen: Dieses Buch bringt Studenten und Wissenschaftlern die Immunologie aktuell und in hervorragender Weise näher. Prof. Dr. Nikolaus Müller-Lantzsch, Universitätskliniken Homburg Die neue Auflage ist kaum noch zu schlagen. Prof. Dr. Stefan H.E. Kaufmann, Max-Planck-Institut für Infektionsbiologie, Berlin Hervorragend. Dieses Lehrbuch genügt sämtlichen Ansprüchen! Prof. Dr. Andreas Dotzauer, Uni Bremen Das Buch besticht durch die hervorragende Vermittlung von Grundlagenwissen, das es in weiterer Folge ermöglicht, auch die komplexen Zusammenhänge bei klinisch-immunologischen Fragestellungen zu verstehen. Prof. Dr. Wolfgang Sipos, Medizinische Universitätsklinik Wien Die auf das wesentliche reduzierten graphischen Darstellungen haben einen besonderen didaktischen Wert, vor allem angesichts der Komplexität dieses Fachgebiets. Prof. Dr. Arne Skerra, TU München Unter den Immunologie-Lehrbüchern nimmt dieses sicher heute den vorderen Rang ein. Es macht Vergnügen, sich von ihm bilden zu lassen. Biospektrum Alles in allem ein wunderbar gestaltetes, umfassendes Lehrbuch, dessen Schwerpunkt deutlich auf der Erklärung grundlegender Mechanismen der Immunabwehr liegt. Naturwissenschaftliche Rundschau Das Buch ist didaktisch hervorragend, vor allem auch in den Abbildungen, und bietet am Ende der Kapitel prägnante Zusammenfassungen, Fragen zum Überprüfen des Gelernten und Hinweise auf Originalarbeiten. Pharmazie in unserer Zeit Uneingeschränkt empfehlenswert; es eignet sich besonders für Biologiestudenten zur Prüfungsvorbereitung, für Mediziner als Nachschlagewerk, aber auch für Studenten und Dozenten anderer Fächer. Chirurgische Praxis Dieses packende moderne Lehrbuch [bietet] jungen Biologen und Medizinern die gegenwärtig beste Möglichkeit, die Mechanismen des Immunsystems in ihrem evolutionären und funktionellen Kontext und medizinischen Bezug kennen zu lernen und vielleicht für ihre eigene zukünftige Tätigkeit zu entdecken. Prof. Dr. Klaus Rajewsky im Vorwort zur 5. Auflage

Encyclopedia Of Immunobiology

Author :
ISBN : 9780080921525
Genre : Medical
File Size : 58. 26 MB
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Encyclopedia of Immunobiology provides the largest integrated source of immunological knowledge currently available. It consists of broad ranging, validated summaries on all of the major topics in the field as written by a team of leading experts. The large number of topics covered is relevant to a wide range of scientists working on experimental and clinical immunology, microbiology, biochemistry, genetics, veterinary science, physiology, and hematology. The book is built in thematic sections that allow readers to rapidly navigate around related content. Specific sections focus on basic, applied, and clinical immunology. The structure of each section helps readers from a range of backgrounds gain important understanding of the subject. Contains tables, pictures, and multimedia features that enhance the learning process In-depth coverage allows readers from a range of backgrounds to benefit from the material Provides handy cross-referencing between articles to improve readability, including easy access from portable devices

Insect Infection And Immunity

Author : Jens Rolff
ISBN : 9780191579141
Genre : Science
File Size : 28. 32 MB
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Under continual attack from both microbial pathogens and multicellular parasites, insects must cope with immune challenges every day of their lives. However, this has not prevented them from becoming the most successful group of animals on the planet. Insects possess highly-developed innate immune systems which have been fine-tuned by an arms race with pathogens spanning hundreds of millions of years of evolutionary history. Recent discoveries are revealing both an unexpected degree of specificity and an indication of immunological memory - the functional hallmark of vertebrate immunity. The study of insect immune systems has accelerated rapidly in recent years and is now becoming an important interdisciplinary field. Furthermore, insects are a phenomenally rich and diverse source of antimicrobial chemicals. Some of these are already being seriously considered as potential therapeutic agents to control microbes such as MRSA. Despite a burgeoning interest in the field, this is the first book to provide a coherent synthesis and is clearly structured around two broadly themed sections: mechanisms of immunity and evolutionary ecology. This novel text adopts an interdisciplinary and concept-driven approach, integrating insights from immunology, molecular biology, ecology, evolutionary biology, parasitology, and epidemiology. It features contributions from an international team of leading experts. Insect Infection and Immunity is suitable for both graduate students and researchers interested in insect immunity from either an evolutionary, genetical, physiological or molecular perspective. Due to its interdisciplinary and concept-driven approach, it will also appeal to a broader audience of immunologists, parasitologists and evolutionary biologists requiring a concise overview.

Evolutionary Conservation Of Developmental Mechanisms

Author : Allan C. Spradling
ISBN : CHI:36830203
Genre : Science
File Size : 88. 43 MB
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An overview of the fundamental mechanisms of multicellular development, focusing on unifying themes in the study of developmental biology. Topics discussed include the role of highly conserved transcription factors in embryonic patterning, generation of distinct germline and soma, transmission and interpretation of information between cells, and evolutionary patterns of sex determination.

Evolutionary Conservation Of Developmental Mechanisms

Author : Society for Developmental Biology. Symposium
ISBN : WISC:89037909389
Genre : Science
File Size : 65. 42 MB
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An overview of the fundamental mechanisms of multicellular development, focusing on unifying themes in the study of developmental biology. Topics discussed include the role of highly conserved transcription factors in embryonic patterning, generation of distinct germline and soma, transmission and interpretation of information between cells, and evolutionary patterns of sex determination.

Somatic Diversification Of Immune Responses

Author : Garnett Kelsoe
ISBN : 3540636080
Genre : Medical
File Size : 20. 26 MB
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Discussing the somatic diversification of immune responses, this monograph covers areas including: the role of promoter-intron interactions in directing hypermutation; the possible role of natural reverse genetics in the V gene loci; and somatic mutagenesis and evolution of memory B cell.

Primitive Immune Systems

Author : Jules Hoffmann
ISBN : NWU:35557000119584
Genre : Drosophila melanogaster
File Size : 30. 11 MB
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