the flaviviruses pathogenesis and immunity the flaviviruses current molecular aspects of evo advances in virus research

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The Flaviviruses Pathogenesis And Immunity

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ISBN : 9780080493824
Genre : Science
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Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts. * Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions. * New, detailed information on the pathogenesis and immunology of the Flavivirus family. * Descibes the technologies that have contributed to our current knowledge about the Flaviviruses. * Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease. * An exhaustive compendium of current and past knowledge on the Flavivirus family

The Flaviviruses Structure Replication And Evolution

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ISBN : 9780080493817
Genre : Science
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Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Structure, Replication and Evolution is the first volume of The Flaviviruses and presents the latest research covering the conceptual advances on aspects such as the characterization of virus structure, cellular receptors, mechanisms of virus entry, host and viral components of the RNA replicase. Includes new, detailed information on the evolution, viral structure and replication of the Flavivirus family The only complete reference book on a major virus family Descibes the technologies that have contributed to our current knowledge about Flaviviruses Identifies the major problems faced in understanding the virus-host interactions that result in disease

Fenner And White S Medical Virology 5

Author : Christopher J. Burrell
ISBN : 9780123751577
Genre : Science
File Size : 49. 16 MB
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Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. Features updated and expanded coverage of pathogenesis and immunity Contains the latest laboratory diagnostic methods Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

Desk Encyclopedia Of Human And Medical Virology

Author : Brian W.J. Mahy
ISBN : 0123785596
Genre : Medical
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This volume contains 82 chapters that provide detail and understanding to the fields of human and medical virology. The first section describes general features of common human viruses with specialized chapters related to HIV/AIDS. The volume goes on to describe exotic virus infections, including one now eradicated virus (smallpox) and some now controlled by vaccination such as yellow fever. Concepts of medical virology are further developed with entries on viruses associated with oncogenesis and selections of interest to medical virology. The most comprehensive single-volume source providing an overview of virology issues related to human and medical applications Bridges the gap between basic undergraduate texts and specialized reviews Concise and general overviews of important topics within the field will help in preparation of lectures, writing reports, or drafting grant applications

Antiviral Drug Discovery For Emerging Diseases And Bioterrorism Threats

Author : Paul F. Torrence
ISBN : 9780471716709
Genre : Medical
File Size : 47. 43 MB
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Antiviral Drug Discovery gives readers a cutting-edge view of how chemical concepts are being mobilized to develop novel approaches that will effectively confront emerging diseases and biowarfare. Among the many topics discussed are smallpox, the Ebola virus, influenza, SARS, arenaviruses and flaviviruses. Each chapter discusses hypothetical strategies for the discovery of relevant antiviral agents, recent findings related to biochemistry or drug discovery, and advances in the further development of established leads in the area. Timely and informative, this book clearly delineates the efforts being made to develop new and effective broad-spectrum antiviral agents.

Molecular Virology And Control Of Flaviviruses

Author : Pei-Yong Shi
ISBN : 9781904455929
Genre : Medical
File Size : 55. 76 MB
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Flaviviruses are a diverse group of small RNA enveloped viruses, many of which are important human and animal pathogens. The best known include dengue virus, yellow fever virus, Japanese encephalitis virus, and West Nile virus. These viruses are endemic in many tropical and sub-tropical regions of the world. Dengue virus alone infects over 100 million people annually. In recent years, research on flaviviruses has progressed at a remarkable rate, leading to significant advances in our understanding of virus biology. This should ultimately lead to the development of better vaccine and antiviral strategies. This up-to-date and cutting-edge anthology contains contributions from the leading experts in the flavivirus field. Chapters are balanced by contributions from established investigators who have dedicated their careers to flavivirus research with those from newcomers who have recently made significant contributions to the flavivirus field. The book is divided into two sections: Molecular Virology and Virus Prevention. The first section on Molecular Virology covers: virion structure * virus replication * the NS1 glycoprotein * the NS3 protein * the NS5 protein * innate immunity and flavivirus infection * host responses to flavivirus infection * flavivirus fitness and transmission. The Virus Prevention section includes: vaccines * antibody therapy * small molecule antiviral development * flavivirus diagnostics * vector-virus interactions * vector control. The book represents an important update of flavivirus research and will serve as a reference to flavivirus researchers at the graduate level and beyond. It is a recommended text for all virology libraries.

Public Health And Infectious Diseases

Author : Jeffrey Griffiths
ISBN : 9780123815071
Genre : Medical
File Size : 63. 10 MB
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Emerging infectious diseases may be defined as diseases being caused by pathogens only recently recognized to exist. This group of diseases is important globally, and the experience of the last 30 years suggests that new emerging diseases are likely to bedevil us. As the global climate changes, so changes the environment, which can support not only the pathogens, but also their vectors of transmission. This expands the exposure and effects of infectious disease and, therefore, the importance of widespread understanding of the relationship between public health and infectious disease. This work brings together chapters that explain reasons for the emergence of these infectious diseases. These include the ecological context of human interactions with other humans, with animals that may host human pathogens, and with a changing agricultural and industrial environment, increasing resistance to antimicrobials, the ubiquity of global travel, and international commerce. * Features the latest discoveries related to influenza with a newly published article by Davidson Hamer and Jean van Seventer * Provides a listing of rare diseases that have become resurgent or spread their geographic distribution and are re-emergent * Highlights dengue and malaria, as well as agents such as West Nile and other arboviruses that have spread to new continents causing widespread concerns * Includes discussions of climate influencing the spread of infectious disease and political and societal aspects

Medizinische Mikrobiologie

Author : Ernest Jawetz
ISBN : 9783662001554
Genre : Science
File Size : 78. 73 MB
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Die Autoren haben beabsichtigt, diejenigen Gebiete der medizinischen Mikrobiologie kurz, exakt und in ihrem gegenwärtigen Stand darzustellen, die für die Infektionskrankheiten und ihre Chemotherapie von besonderer Bedeutung sind. Das Buch wendet sich in erster Linie an Medizinstudenten, außerdem an alle Ärzte in Krankenhaus und Praxis. Die Notwendigkeit für ein klares Verständnis der mlkrobiologischen Grundtatsachen ist in den letzten Jahren stärker geworden, da in Biochemie, Virologie und Chemotherapie so wie auf weiteren, die Medizin beeinflussenden Gebieten bedeutende Entwicklungen statt gefunden haben. Ein wesendicher Teil dieses Lehrbuches ist deswegen der Darstellung der Grundlagen gewidmet, wodurch sich das Buch auch für die Einführung des Studenten in den mikrobiologischen Kurs als brauchbar erweisen wird. Für die neue Auflage wurde ein Kapitel über Virus und Krebs neu geschrieben, und das Kapitel über antimikrobielle Chemotherapie wurde von Grund auf neu bearbeitet. Die Autoren freuen sich, bei dem Erscheinen der 7. amerikanischen Ausgabe von einer spanischen, deutschen, italienischen und griechischen Ausgabe, sowie von der Vorbereitung für eine serbokroatische Übersetzung berichten zu können. Die Autoren möchten nochmals allen danken, die ihnen bei der Bearbeitung dieser Auf lage behilflich waren, und die es ihnen durch ihre Kommentare und ihre Kritik ermöglicht haben, die in 2jährigen Abständen erscheinenden Revisionen dieses Buches auf dem neu esten Stand zu halten. ERNEsr JAWETZ JOSEPH L MELNICK San Frandsco, August 1966 EnWARD A AnELBERG III Inhaltsverzeichnis 1 Kapitell Die ~lt der Mikroben 8 Kapitel 2 Cytologie der Bakterien Optische Methoden 8 9 Eukaryote Zellstrukturen Prokaryote Zellstrukturen . 12 14 Cytoplasmatische Strukturen. 27 Färbeverfahren .

Ob Dir Es Sauer Wird Mit Deiner Nahrung Und Ackerwerk Das La Dich Nicht Verdrie En Denn Gott Hat Es Also Geschaffen

Author : Katharina Ruttig
ISBN : 9783863950224
Genre : Botanists
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Der aus Westfalen stammende Gottfried Dietrich Wilhelm Berthold (1854- 1937) ist als Botaniker des 19. und beginnenden 20. Jahrhunderts eng mit der Geschichte der Georgia Augusta in Göttingen verwoben. Er hatte sich bereits als Student an der Universität Göttingen mit Algen beschäftigt und seine Dissertation dieser Thematik gewidmet. Nach Forschungsaufenthalten an der Zoologischen Station in Neapel, wo er intensiv Untersuchungen an Algen durchführte, habilitierte er sich 1881 in Göttingen bei Johannes Reinke. Später übernahm er dessen Professur für Botanik sowie dessen Direktorat am Pflanzenphysiologischen Institut und widmete sich entwicklungsmechanischen bzw. physiologischen Fragen bei höheren Pflanzen. Die vorliegende Monografie untersucht erstmalig anhand der gegenwärtigen Forschungslage Leben und Wirken Bertholds. Bertholds Lebensgeschichte wird chronologisch und in größtmöglicher Vollständigkeit dargestellt. Bildungsgeschichtliche Akzente, der personelle Konnex zu Johannes Reinke und der Einfluss der Zoologischen Station Neapel finden hier ebenso Platz wie die Rekonstruktion der Lehr- und Forschungstätigkeiten und der familiären Verhältnisse. Da Berthold vorrangig als Phykologe, also Algenkundler anzusehen ist, widmet sich der zweite Teil dem Forschungsschwerpunkt Algen. Dabei werden vor allem die meeresbiologischen Aspekte seiner Forschung am Golf von Neapel untersucht. Bertholds unterschiedliche Lebensstationen können in Zusammenhang mit seinen Publikationen betrachtet werden, dieser Teil untersucht daher das wissenschaftliche Wirken Bertholds. Anhand der aktuellen Quellenlage wird der Bestand seiner Werke aufgearbeitet und katalogisiert. Die vollständige Bibliografie ermöglicht die Bestimmung von Schwerpunkten in Bertholds wissenschaftlichen Untersuchungen. So bietet diese erste Monografie über Gottfried D.W. Berthold ein Fundament für die Beurteilung seines OEuvres und seiner Wirkung auf die Phykologie bzw. die Botanik. Sie ist eine angemessene Erinnerung an ihn und ermöglicht eine gebührende Würdigung seines Wirkens. Die vorliegende Studie ist ein Beitrag zur Universitäts- und Wissenschaftsgeschichte der Georgia Augusta.

Government Reports Announcements Index

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ISBN : STANFORD:36105013141671
Genre : Science
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