the oncogene and tumour suppressor gene factsbook

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The Oncogene And Tumour Suppressor Gene Factsbook

Author : Robin Hesketh
ISBN : 0080538002
Genre : Medical
File Size : 49. 35 MB
Format : PDF
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The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including JUN, MYC, and RAS, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy. Includes much new data on this fast-moving field, including newly discovered oncogenes Summarizes the clinical association and molecular properties of all known oncogenes and tumor suppression genes Contains more than 2000 terms for reference and further research Revised to included signaling pathways, apoptosis, and metastasis

The Gene Knockout Factsbook Two Volume Set

Author :
ISBN : 0080532365
Genre : Science
File Size : 43. 52 MB
Format : PDF, ePub, Mobi
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The FactsBooks Series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "a growing series of excellent manuals" by Molecular Medicine Today, and "essential works of reference" by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format and drawing from meticulous research, the Factsbooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity. The Gene Knockout FactsBook contains entries, grouped into subject disciplines, covering immunology, neurobiology, development, cancer, and other knockouts. It describes more than 600 gene knockouts described and listed in alphabetical order for easy reference. Key Features * Entries provide information on: * general description of the protein and its function * gene symbol and database accession number * knockout construct * mouse phenotype * key references

The Leucocyte Antigen Factsbook

Author : A. Neil Barclay
ISBN : 9780080535432
Genre : Medical
File Size : 69. 55 MB
Format : PDF, Docs
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A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references. The introductory chapters have also been updated, especially in terms of nomenclature, the role of the World Wide Web, and new structural data. The Leucocyte Antigen FactsBook, Second Edition contains more than 200 entries, with approximately 70 new entries, on all the molecules specifically expressed in the surface of cells of the haematopoietic system, including all characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors. This FactsBook will be of enormous value to immunologists, cell biologists, biochemists, and endocrinologists. Key Features * Completely up-to-date * Revised and expanded to include over 70 new entries * More than 200 entries in total, plus additional introductory material * New structural data * New nomenclature for CD and related molecules covered

The Immunoglobulin Factsbook

Author : Marie-Paule Lefranc
ISBN : 9780080574479
Genre : Medical
File Size : 56. 19 MB
Format : PDF, ePub, Docs
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The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field. The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.

The Nuclear Receptor Factsbook

Author : Vincent Laudet
ISBN : 0124377351
Genre : Medical
File Size : 73. 6 MB
Format : PDF, ePub, Docs
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The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure Isolation DNA binding properties Ligands Expression Target genes Knockouts Disease association Gene structure, promoter and isoforms Chromosomal location Amino acid sequences Key references

The T Cell Receptor Factsbook

Author : Marie-Paule Lefranc
ISBN : 0080542646
Genre : Medical
File Size : 57. 20 MB
Format : PDF, ePub, Mobi
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The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.

Oncogene Directed Therapies

Author : Janusz W. Rak
ISBN : 9781592593132
Genre : Medical
File Size : 59. 20 MB
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Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.

The Ion Channel Factsbook

Author : Edward C. Conley
ISBN : WISC:89066560319
Genre : Ion channels
File Size : 67. 48 MB
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Each entry includes data on nomenclatures, expression, sequence, analyses, structure and functions, electrophysiology, pharmacology, and information retrieval.

European Journal Of Gynaecological Oncology

Author :
ISBN : UCLA:L0090458035
Genre :
File Size : 25. 22 MB
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Harrison S Principles Of Internal Medicine

Author : Dennis L. Kasper
ISBN : 9780071477604
Genre : Medical
File Size : 52. 50 MB
Format : PDF, ePub
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THE NEW COLOR OF MEDICINE HUNDREDS OF DIAGRAMS AND CLINICAL PHOTOS INTEGRATED INTO THE TEXT – FOR THE FIRST TIME IN FULL COLOR *This description refers to the single-volume of Harrison's Principles of Internal Medicine, 16/e. The Harrison's name is synonymous with internal medicine. HPIM continues to be the most authoritative and #1 selling medical textbook throughout the world. From its unique section on signs and symptoms through to the most comprehensive coverage of most all conditions seen by physician’s, Harrison's is the internal medicine reference of choice. Harrison's 16th Edition features new, expanded, revised and updated material on the key topics in medical practice today. From the latest research findings to up-to-the-minute advances in diagnostic and treatment methodologies, Harrison's puts the facts you need at your fingertips. The 16th Edition improves on a winning formula with: *State-of-the-art coverage of over 4,700 diseases and disorders—more than any other internal medicine text – in the areas of oncology and hematology; infectious diseases; cardiology; pulmonology; gastroenterology; clinical immunology; rheumatology; endocrinology; and neurology *A brand new full color format—665 full color drawings, 175 clinical and laboratory images, and hundreds of boxes, tables, and algorithms that use color to guide you to the information you need ASAP in everyday patient care *Thorough revision and updates of virtually all chapters *The addition of key new chapters – including extensive new coverage of Critical Care Medicine *145 algorithms for making accurate clinical decisions fast at the point of care *1,160 easy-access tables for immediate access to vital information and formulas *Cardinal manifestations of disease/signs and symptoms in 55 chapters (you’ll find yourself turning to this section over and over again). Here you will find all the major manifestations, such as fever, pain, aches and rash, presented in depth, with a referral that takes you to the disease section for the complete chapter. Stay a step ahead of everyday practice with the most authoritative, comprehensive, and useful guide to the entire spectrum of internal medicine.

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