the oncogene and tumour suppressor gene factsbook

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The Oncogene And Tumour Suppressor Gene Factsbook

Author : Robin Hesketh
ISBN : 0080538002
Genre : Medical
File Size : 62. 8 MB
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The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including JUN, MYC, and RAS, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy. Includes much new data on this fast-moving field, including newly discovered oncogenes Summarizes the clinical association and molecular properties of all known oncogenes and tumor suppression genes Contains more than 2000 terms for reference and further research Revised to included signaling pathways, apoptosis, and metastasis

The Gene Knockout Factsbook Two Volume Set

Author :
ISBN : 0080532365
Genre : Science
File Size : 40. 44 MB
Format : PDF, Kindle
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The FactsBooks Series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "a growing series of excellent manuals" by Molecular Medicine Today, and "essential works of reference" by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format and drawing from meticulous research, the Factsbooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity. The Gene Knockout FactsBook contains entries, grouped into subject disciplines, covering immunology, neurobiology, development, cancer, and other knockouts. It describes more than 600 gene knockouts described and listed in alphabetical order for easy reference. Key Features * Entries provide information on: * general description of the protein and its function * gene symbol and database accession number * knockout construct * mouse phenotype * key references

The Leucocyte Antigen Factsbook

Author : A. Neil Barclay
ISBN : 9780080535432
Genre : Medical
File Size : 74. 74 MB
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A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references. The introductory chapters have also been updated, especially in terms of nomenclature, the role of the World Wide Web, and new structural data. The Leucocyte Antigen FactsBook, Second Edition contains more than 200 entries, with approximately 70 new entries, on all the molecules specifically expressed in the surface of cells of the haematopoietic system, including all characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors. This FactsBook will be of enormous value to immunologists, cell biologists, biochemists, and endocrinologists. Key Features * Completely up-to-date * Revised and expanded to include over 70 new entries * More than 200 entries in total, plus additional introductory material * New structural data * New nomenclature for CD and related molecules covered

The Immunoglobulin Factsbook

Author : Marie-Paule Lefranc
ISBN : 9780080574479
Genre : Medical
File Size : 35. 86 MB
Format : PDF
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The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field. The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.

The Nuclear Receptor Factsbook

Author : Vincent Laudet
ISBN : 0124377351
Genre : Medical
File Size : 79. 18 MB
Format : PDF, ePub, Mobi
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The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure Isolation DNA binding properties Ligands Expression Target genes Knockouts Disease association Gene structure, promoter and isoforms Chromosomal location Amino acid sequences Key references

The T Cell Receptor Factsbook

Author : Marie-Paule Lefranc
ISBN : 0080542646
Genre : Medical
File Size : 70. 11 MB
Format : PDF
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The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.

The Oncogene Factsbook

Author : Robin Hesketh
ISBN : 0123445507
Genre : Oncogenes
File Size : 59. 86 MB
Format : PDF, Mobi
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The Oncogene FactsBook is a condensed version of the Oncogene Handbook, in the FactsBook Series format. The key information on oncogenes, tumor viruses, and tumor suppressor genes has been selected from the Handbook and arranged in the series style to that the essential information is readily accessible. The introduction summarizes the principal developments in our understanding of oncogenes, the presente position with regard to gene therapy for human cancers, and discusses patterns of oncogene expression in human tumors. Chapter 2 contains tables of the major categories of oncogenes that include a summary of the properties of those oncogenes which do not have individual sections. Chapter 3 covers the individual oncogenes in a constant format for each entry. DNA tumor viruses and tumor suppressor genes are considered separately in two sections. The minimum number of references has been included in order to give the reader rapic access to the literature in the key areas of structure and function of each gene and its product. The emphasis has thus been placed on listing the most up-to-date references, rather than an extensive bibliography. The Oncogene FacsBook contains more that 60 entries on oncogenes including: JUN, MAS, MYC, MAX, and RAS, as well as DNA tomur viruses, tumor suppressor genes, and essential introductory material. * Individual Oncogene Entries include: * Identification * Related genes * Chromosomal Location and Mass * Cellular Location * Tissue Distribution * Protein function * Cancer * Amino acid Sequence * Domain structure * Database accession numbers * Key references

Oncogene Directed Therapies

Author : Janusz W. Rak
ISBN : 9781592593132
Genre : Medical
File Size : 84. 36 MB
Format : PDF, Kindle
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Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.

Harrison S Principles Of Internal Medicine 19 E Vol 1 Vol 2

Author : Dennis L. Kasper
ISBN : 9780071802161
Genre : Medical
File Size : 90. 60 MB
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The landmark guide to internal medicine— updated and streamlined for today’s students and clinicians The only place you can get ALL the great content found in the two print volumes AND the acclaimed DVD in one convenient resource! Through six decades, no resource has matched the authority, esteemed scholarship, and scientific rigor of Harrison’s Principles of Internal Medicine. Capturing the countless advances and developments across the full span of medicine, the new 19th edition of Harrison’s provides a complete update of essential content related to disease pathogenesis, clinical trials, current diagnostic methods and imaging approaches, evidence-based practice guidelines, and established and newly approved treatment methods. Here are just a few of the outstanding features of the new Nineteenth Edition: Content is practically organized around two basic themes: education and clinical practice The teaching and learning sections cover foundational principles, cardinal manifestations of disease and approach to differential diagnosis; the content devoted to clinical practice focuses on disease pathogenesis and treatment NEW chapters on important topics such as Men’s Health, The Impact of Global Warming on Infectious Diseases, Fatigue, and many more Critical updates in management and therapeutics in Hepatitis, Coronary Artery Disease, Ebola Virus Disease, Multiple Sclerosis, Diabetes, Hypertension, Deep Vein Thrombosis and Pulmonary Embolism, Acute and Chronic Kidney Disease, Inflammatory Bowel Disease, Lipoprotein Disorders, HIV and AIDS, and more. Increased number of the popular Harrison’s clinical algorithms; clinically relevant radiographic examples spanning hundreds of diseases; clinical-pathological images in full color; crystal clear, full color drawings and illustrations and helpful tables and summary lists that make clinical application of the content faster than ever Outstanding multi-media resources including practical videos demonstrating essential bedside procedures, physical examination techniques, endoscopic findings, cardiovascular findings, are available for easy download Supporting the renowned coverage are supplemental resources that reflect and assist modern medical practice: more than 1,000 full-color photographs to aid visual recognition skills, hundreds of state-of-the-art radiographs, from plain film to 3D CT to PET Scans; beautiful illustrations that bring applied anatomy and processes to life; the renowned Harrison’s patient-care algorithms, essential summary tables, and practical demonstrative videos. In addition, several digital atlases highlight noninvasive imaging, percutaneous revascularization, gastrointestinal endoscopy, diagnosis and management of vasculitis, and numerous other issues commonly encountered in clinical practice. Acclaim for Harrison’s: “Covering nearly every possible topic in the field of medicine, the book begins with a phenomenal overview of clinical medicine, discussing important topics such as global medicine, decision-making in clinical practice, the concepts of disease screening and prevention, as well as the importance of medical disorders in specific groups (e.g. women, surgical patients, end of life). The extensive chapters that follow focus on a symptom-based presentation of disease and then illness organized by organ system. Numerous tables, graphs, and figures add further clarity to the text." ...Written by experts in the field, this book is updated with the latest advances in pathophysiology and treatment. It is organized in a way that makes reading from beginning to end a logical journey, yet each chapter can stand alone as a quick reference on a particular topic. “ Doody’s Review Service reviewing the previous edition of Harrison’s

Harrison S Hematology And Oncology

Author : Dan L. Longo
ISBN : 9780071663366
Genre : Medical
File Size : 75. 35 MB
Format : PDF, ePub, Mobi
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Market: oncologists (20,000), hematologists (15,000), oncology fellows (2,500), hematology fellows (2000), internal medicine residents (23,000), internists (75,000), family practice residents and clinicians (55,000), cancer-care nursing (40,000), first and second year medical students (18,000/year)

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