the prefrontal cortex

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The Prefrontal Cortex

Author : Joaquin Fuster
ISBN : 9780124080607
Genre : Medical
File Size : 39. 71 MB
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The Prefrontal Cortex, Fifth Edition, provides users with a thoroughly updated version of this comprehensive work that has historically served as the classic reference on this part of the brain. The book offers a unifying, interdisciplinary perspective that is lacking in other volumes written about the frontal lobes, and is, once again, written by the award-winning author who discovered "memory cells," the physiological substrate of working memory. The fifth edition constitutes a comprehensive update, including all the major advances made on the physiology and cognitive neuroscience of the region since publication in 2008. All chapters have been fully revised, and the overview of prefrontal functions now interprets experimental data within the theoretical framework of the new paradigm of cortical structure and dynamics (the Cognit Paradigm), addressing the accompanying social, economic, and cultural implications. Provides a distinctly interdisciplinary view of the prefrontal cortex, covering all major methodologies, from comparative anatomy to modern imaging Unique analysis and synthesis of a large body of basic and clinical data on the subject (more than 2000 references) Written by an award-winning author who discovered "memory cells," the physiological substrate of working memory Synthesizes evidence that the prefrontal cortex constitutes a complex pre-adaptive system Incorporates emerging study of the role of the frontal lobes in social, economic, and cultural adaptation

Prefrontal Cortex

Author : Satoru Otani
ISBN : 9781402079498
Genre : Medical
File Size : 25. 21 MB
Format : PDF
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This volume, Prefrontal Cortex: from Synaptic Plasticity to Cognition, is an interdisciplinary approach to characterize the function of the anterior portion of the frontal lobe in rodents and human and non-human primates. The specific topics discussed in the chapters of this volume are purposefully diverse: they range from membrane properties of prefrontal neurons to cognitive psychology. Nevertheless, this volume must not be regarded as a mere collection of writings with the different sub-themes. As you will see, chapters often vigorously encompass domains of the prefrontal field in effort to provide a big picture. That is actually what we attempted to do in this volume. On one hand, we have accumulated knowledge on the properties of neurons and synapses in the prefrontal cortex as well as the actions of critical neuromodulators such as dopamine. On the other hand, behavioral and cognitive neurosciences have begun to reveal the fascinating role of the prefrontal cortex in such mental processes as working memory, attention switching and rule following, and long-term memory. Needless to say, our ultimate goal as neurobiologists is to know what relationship there is between these cellular and cognitive processes. This volume is meant to serve as a comprehensive introduction towards that goal. Readers will be informed, for example, of how plasticity of prefrontal neurons is regulated, how it is involved in certain cognitive processes in rodents, and how the rodent models can apply to the primates.

The Neurobiology Of The Prefrontal Cortex

Author : Richard E. Passingham
ISBN : 9780191633096
Genre : Medical
File Size : 29. 48 MB
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The prefrontal cortex makes up almost a quarter of the human brain, and it expanded dramatically during primate evolution. The Neurobiology of the Prefrontal Cortex presents a new theory about its fundamental function. In this important new book, the authors argue that primate-specific parts of the prefrontal cortex evolved to reduce errors in foraging choices, so that particular ancestors of modern humans could overcome periodic food shortages. These developments laid the foundation for working out problems in our imagination, which resulted in the insights that allow humans to avoid errors entirely, at least at times. In the book, the authors detail which parts of the prefrontal cortex evolved exclusively in primates, how its connections explain why the prefrontal cortex alone can perform its function, and why other parts of the brain cannot do what the prefrontal cortex does. Based on an analysis of its evolutionary history, the book uses evidence from lesion, imaging, and cell-recording experiments to argue that the primate prefrontal cortex generates goals from a current behavioural context and that it can do so on the basis of single events. As a result, the prefrontal cortex uses the attentive control of behaviour to augment an older general-purpose learning system, one that evolved very early in the history of animals. This older system learns slowly and cumulatively over many experiences based on reinforcement. The authors argue that a new learning system evolved in primates at a particular time and place in their history, that it did so to decrease the errors inherent in the older learning system, and that severe volatility of food resources provided the driving force for these developments. Written by two leading brain scientists, The Neurobiology of the Prefrontal Cortex is an important contribution to our understanding of the evolution and functioning of the human brain.

The Prefrontal Cortex Its Structure Function And Pathology

Author : J.P.C. de Bruin
ISBN : 9780080862101
Genre : Medical
File Size : 34. 1 MB
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Thanks to a resurgence of interest and a recent proliferation of research techniques, much new and illuminating data has emerged during the last decade relating to the prefrontal cortex, particularly in primates and rodents. In view of this progress, the 16th International Summer School of Brain Research was held in Amsterdam, The Netherlands from 28 August to 1 September 1989, devoted to the topic of `The Prefrontal Cortex: Its Structure, Function and Pathology'. The edited proceedings, embodied in this 85th volume of `Progress in Brain Research', fall into three sections - the first of which, following two introductory chapters, discusses the present knowledge of the organization of prefrontal cortical systems. In the second section, developmental and plasticity aspects in rodent and human cortex are considered, whilst the third section deals extensively with the functional aspects characteristic for the prefrontal cortex in primates, rats and rabbits. The last section reviews several topics on dysfunction of prefrontal cortex in rat and man, including a historical review on psychosurgery.

Development Of The Prefrontal Cortex

Author : Norman A. Krasnegor
ISBN : STANFORD:36105019324115
Genre : Science
File Size : 65. 40 MB
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In this scholarly reference, notable investigators in the fields of neuroscience and behavior examine research findings concerning the prefrontal cortex. Readers will explore evolutionary issues, brain-behavior relationships, and the neurobiology, neuropsychology, and neuropathology of this important region of the brain.

The Prefrontal Cortex As An Executive Emotional And Social Brain

Author : Masataka Watanabe
ISBN : 9784431565086
Genre : Medical
File Size : 73. 82 MB
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This book is devoted to the executive, emotional, social, and integrative functions of the prefrontal cortex (PFC). The PFC has usually been studied only with its executive function or with its emotional function, but recent studies indicate that the PFC plays important roles in integrating executive and emotional functions as well as in social behavior. The first part of the book reviews the functional organization of the PFC in human and nonhuman primates. The subsequent part focuses on the integrator of executive and emotional functions. The third part presents the integrator of executive and social functions, and the final part discusses the default mode of brain activities. There are chapters on animal studies, because functional significance of the PFC cannot be described without referring to those studies. Thus many methodologies are presented such as human neuropsychological, neuroimaging, and stimulation studies, and animal neuropsychological, neurophysiological, neurochemical, neuroanatomical, and neuroimaging studies. Bringing those together, this volume provides a timely and concise picture of the function of the PFC. The result is a valuable resource for students and scientists, providing up-to-date information on this emerging research topic.

The Prefrontal Cortex

Author : A. Angela C. Roberts
ISBN : 0198524412
Genre : Medical
File Size : 68. 4 MB
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The prefrontal cortex, one of the most important areas of research in contemporary neuropsychology, appears to be linked with executive processes affecting many diverse areas of cognition, including working memory, information processing, behavioral organization, and attention. This state-of-the-art account of our knowledge of the prefrontal cortex brings together contributions from some of the world's leading researchers on the subject. The authors discuss the many recent theoretical and technical advances in the field--from advances in our understanding of the neural architecture of the prefrontal cortex to the use of functional neuroimaging and from new ideas about the relationships between neuronal activity and behavior to comparisons between human and non-human primate cognition. One of the first books to be written on the subject, The Prefrontal Cortex will be important reading for all researchers and students in neuro- and cognitive psychology, and neuroscience.

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