therapeutic antibodies 181 handbook of experimental pharmacology

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Therapeutic Antibodies

Author : Yuti Chernajovsky
ISBN : 3540732594
Genre : Medical
File Size : 47. 10 MB
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This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.

Safety Of Biologics Therapy

Author : Brian A. Baldo
ISBN : 9783319304724
Genre : Medical
File Size : 63. 73 MB
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This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.

Drug Drug Interactions For Therapeutic Biologics

Author : Honghui Zhou
ISBN : 9781118630211
Genre : Medical
File Size : 79. 44 MB
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Strategize, plan, and execute comprehensive drug-druginteraction assessments for therapeutic biologics Offering both theory and practical guidance, this book fullyexplores drug-drug interaction assessments for therapeuticbiologics during the drug development process. It draws togetherand analyzes all the latest findings and practices in order topresent our current understanding of the topic and point the way tonew research. Case studies and examples, coupled with expertadvice, enable readers to better understand the complex mechanismsof biologic drug-drug interactions. Drug-Drug Interactions for Therapeutic Biologics featurescontributions from leading international experts in all areas oftherapeutic biologics drug development and drug-drug interactions.The authors' contributions reflect a thorough review and analysisof the literature as well as their own firsthand laboratoryexperience. Coverage includes such essential topics as: Drug-drug interaction risks in combination with small moleculesand other biologics Pharmacokinetic and pharmacodynamic drug-drug interactions In vitro methods for drug-drug interaction assessment andprediction Risk-based strategies for evaluating biologic drug-druginteractions Strategies to minimize drug-drug interaction risk and mitigatetoxic interactions Key regulations governing drug-drug interaction assessments fortherapeutic biologics. Drug-Drug Interactions for Therapeutic Biologics isrecommended for pharmaceutical and biotechnology scientists,clinical pharmacologists, medicinal chemists, and toxicologists. Byenabling these readers to understand how therapeutic biologics mayinteract with other drugs, the book will help them develop safer,more effective therapeutic biologics.

Current Developments In Biotechnology And Bioengineering

Author : Vanete Thomaz Soccol
ISBN : 9780444636713
Genre : Science
File Size : 82. 41 MB
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Current Developments in Biotechnology and Bioengineering: Human and Animal Health Applications provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, presenting data-based scientific knowledge and information on medical biotechnological interventions for human and animal health. Drawing on the key development areas in this field, the book reviews biotechnological advances and applications in immunotechnology, vaccines and vaccinology, combinatorial libraries, gene and cell therapy, tissue engineering, and parasite and infectious disease diagnostics. This title outlines why biotechnological techniques in these areas are useful in a clinical context and considers their potential uses, limitations, and the ethical considerations surrounding their use. Provides development in human and animal health due to biotechnology Includes immunotechnology and vaccinology Outlines diagnostic techniques based on tissue and metabolic engineering principles Considers potential uses of the various biotechnology based techniques and the ethical issues raised in their use

Cancer Immunology

Author : Nima Rezaei
ISBN : 9783662464106
Genre : Medical
File Size : 34. 1 MB
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Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. This volume focuses on the immunopathology and immunotherapy of organ cancers in detail. It clearly explains their immunology and describes novel immunotherapy for specific cancers, including pediatric solid tumors, hematologic malignancies, gastrointestinal tumors, skin cancers, bone and connective tissue tumors, central nervous system tumors, lung cancers, genitourinary tract tumors and breast cancers. In so doing, it builds on the previous two volumes in Cancer Immunology, placing basic knowledge on tumor immunology and immunotherapy into a clinical perspective with the aim of educating clinicians on advances in cancer immunology and the most recent approaches in the immunotherapy of various tumors. This translational, clinically oriented book will be of special value to clinical immunologists, hematologists and oncologists.

Alternatives To Laboratory Animals

Author :
ISBN : UCLA:L0090618208
Genre : Biological models
File Size : 75. 58 MB
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Handbuch Der Experimentellen Pharmakologie

Author :
ISBN : PSU:000065384527
Genre :
File Size : 25. 29 MB
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Pharmacology And Therapeutics For Dentistry E Book

Author : John A. Yagiela
ISBN : 9780323078245
Genre : Medical
File Size : 88. 4 MB
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Use your knowledge of pharmacology to enhance oral care! Pharmacology and Therapeutics for Dentistry, 6th Edition describes how to evaluate a patient’s health and optimize dental treatment by factoring in the drugs they take. It explores the basic fundamentals of pharmacology, special topics such as pain control, fear and anxiety, and oral complications of cancer therapy, and most importantly, the actions of specific drug groups on the human body. Whether you’re concerned about the drugs a patient is already taking or the drugs you prescribe for treatment, this book helps you reduce risk and provide effective dental care. An emphasis on the dental applications of pharmacology relates drugs to dental considerations in clinical practice. Dental aspects of many drug classes are expanded to include antibiotics, analgesics, and anesthetics. The Alternative Medicine in Dentistry chapter discusses chemicals used as alternative medicines and assesses their potential benefits and risks. The Nonopioid Analgesics chapter groups together non-opioid analgesics, nonsterioidal anti-inflammatory drugs, and antirheumatic and antigout drugs, making these easier to locate and study. Coverage of the endocrine system includes four separate chapters for the most comprehensive coverage. Drug Interactions in Clinical Dentistry appendix lists potential interactions between drugs a patient is taking for nondental conditions and drugs that may be used or prescribed during dental treatment, including effects and recommendations. Glossary of Abbreviations appendix includes the most common abbreviations used for drugs or conditions. New Pharmacogenetics and Pharmacogenomics chapter covers the effects of genetic traits of patients on their responses to drugs. A NEW introductory section offers tips for the study of dental pharmacology and relates pharmacology to dental considerations. An updated discussion of drug-drug interactions covers the harmful effects of mixing medications. Coverage of adverse effects and mechanisms of COX-2 inhibitors, antibiotic prophylaxis, and antiplaque agents explains the dental risks relating to common drug treatments.

The Journal Of Pharmacology And Experimental Therapeutics

Author :
ISBN : UCAL:B5014723
Genre :
File Size : 45. 40 MB
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Pharmacology And Therapeutics For Dentistry

Author : John A. Yagiela
ISBN : UOM:39015026856941
Genre : Dental pharmacology
File Size : 58. 91 MB
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