transport and diffusion across cell membranes

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Transport And Diffusion Across Cell Membranes

Author : Wilfred Stein
ISBN : 9780323143202
Genre : Science
File Size : 22. 48 MB
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Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

Transport And Diffusion Across Cell Membranes

Author : Wilfred D. Stein
ISBN : UOM:39015053998475
Genre : Science
File Size : 54. 78 MB
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Molecular Mechanisms Of Water Transport Across Biological Membranes

Author : Thomas Zeuthen
ISBN : 0123646197
Genre : Science
File Size : 71. 71 MB
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International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume looks at water movements from a wide range of levels. It examines how water interacts with the major components of the cell, including proteins and lipids. It discusses how water moves across cell membranes by diffusion, how it is chanelled across these membranes or, in certain cases, pumped across, and how water movements are controlled. This book demonstrates how water and ion movements are closely linked in order to provide a better understanding of their behavior. *Essential Physical chemistry of water at biological interfaces *Up-to-date reviews of water behavior in cells *Water in integrated systems *Current information on water channels across membranes


Author : David W. Lawlor
ISBN : 313737801X
Genre : Photosynthesis
File Size : 48. 58 MB
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Water Transport And Biological Membranes

Author : Gheorghe Benga
ISBN : 9781351094559
Genre : Medical
File Size : 35. 83 MB
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The main purpose of this book is to provide in-depth presentation of physical techniques for measuring water transport and their applications to a variety of biological membranes, from model membrane systems to cell membranes, and then from isolated cells to multicellular barrier systems, such as epithelia or even whole organisms. This survey of water transport in such a broad range of membrane systems will hopefully contribute to understanding of the structure-function relationships and molecular mechanisms of water permeation. Moreover, the description of various techniques, together with a review of literature will enable the readers to assess whether a technique would be useful in helping to solve his or her particular problem of research and will also expand their competence in these techniques. The book consists of two volumes.

The Movement Of Molecules Across Cell Membranes

Author : W Stein
ISBN : 9780323152679
Genre : Science
File Size : 80. 36 MB
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The Movement of Molecules across Cell Membranes provides an understanding of the molecular basis of the movement of substances across the cell membrane by discussing the composition and structure of cell membranes. Comprised of nine chapters, the book starts by discussing the theory of irreversible thermodynamics to membrane transport, followed by a discussion of the Eyring analysis of diffusion. It then discusses the model for movement into and across the cell membranes. Other chapters focus on the existence of pores in the red cell membranes and the ion movement across the erythrocyte membranes. The book's final chapter considers the four classifications of membrane-based models, which include the mobile carrier model, the pore model, and the two classes of enzyme models. This book is intended for research students, research workers, biochemists, biophysicists, and physiologists. Pharmacologists in the clinical field, as well as research workers in agriculture, will also find this book invaluable.

Channels Carriers And Pumps

Author : Wilfred D. Stein
ISBN : 9780124165830
Genre : Science
File Size : 73. 1 MB
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An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building

Cell Membrane Transport

Author : Arnost Kotyk
ISBN : 9781461344131
Genre : Science
File Size : 86. 20 MB
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TO THE SECOND EDITION When preparing the manuscript for the original edition of this book we were only partly aware of the pace at which the field of membrane transport was developing and at which new ideas as well as new techniques would be applied to it. The fact is that some of the chapters are now outdated (e. g. , the one on the molecular aspects of transport) and many others require revision in the light of new information that has appeared in the past five years. However, it is also true that we overemphasized in the first edition certain points that now appear less important and underestimated the impact of certain others that have since assumed a position among the most forcefully discussed topics of membrane research. In making amends, it was thus thought useful to include the discussion of these latter problems both in the theoretical and in the comparative sections and, on the other hand, to omit some of the less topical subjects. There was a different reason for rewriting the section on kidney and for dropping the section on mito chondria. The help of an expert nephrologist was enlisted for improving chapter 24, while it was decided that mitochondria represent a special field both conceptually (being only subcellular particles) and methodologically (more indirect estimation techniques being involved than with whole cells or tissues) and that more adequate information can be found in treatises specializing in work with mitochondria.

Biomembranes Passive Permeability Of Cell Membranes

Author : F. Kreuzer
ISBN : 9781468409611
Genre : Science
File Size : 35. 68 MB
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Pharmacology For The Primary Care Provider E Book

Author : Marilyn Winterton Edmunds
ISBN : 9780323087919
Genre : Medical
File Size : 49. 70 MB
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Written by and for nurse practitioners, and also suitable for physician’s assistants, Pharmacology for the Primary Care Provider, 4th Edition focuses on what you need to know to safely and effectively prescribe drugs for primary care. An emphasis on patient teaching helps you gain patient adherence to prescribed drug regimens, and guidelines for health promotion help in maintaining and improving your patients’ health. Now in full color, this edition expands the book's emphasis on the QSEN priorities of safety and evidence-based practice, and adds coverage of new drugs, new drug classes, and new therapeutic drug uses. Written by leading nurse practitioner authorities Marilyn Winterton Edmunds and Maren Stewart Mayhew, Pharmacology for the Primary Care Provider teaches principles of pharmacotherapeutics using today’s most commonly used drugs. A Key Drugs focus highlights the most commonly used and most representative drugs of each major drug class — with particular emphasis on the top 100 most commonly prescribed drugs. Emphasis on patient teaching helps you communicate with patients and family caregivers to promote adherence to the drug regimen. Emphasis on health promotion describes how to help patients stay well and improve their health, including coverage of immunizations and biologicals, vitamins, weight management, and smoking cessation. Evidence-Based Decision-Making and Treatment Guidelines chapter (11) provides practical guidelines for using the best current research evidence to make decisions about the care of individual patients. Extensive coverage of drug therapy for special populations such as geriatric and pediatric patients includes considerations related to age, pregnancy, race, and other factors. UNIQUE! Coverage of prescriptive practice includes topics such as prescriptive authority, role implementation, and the role of nurses (NPs, CNMs, CRNAs, and CNSs) and physician assistants in writing prescriptions. NEW! Full-color design and illustrations highlight the most important content. DRUG UPDATES reflect the latest FDA-approved drugs, drug classes, and therapeutic uses. Expanded emphasis on the QSEN priorities of safety and evidence-based practice helps you eliminate drug prescribing errors with color-highlighted Safety Alerts! and NEW Clinical Practice Alerts! NEW section on male hormone replacement therapies adds coverage of men to that for women. Updated evidence-based prescribing information reflects the latest national clinical practice guidelines and evidence-based treatment guidelines, including the latest clinical treatment guidelines for diabetes. NEW! Complementary and Alternative Products tables highlight interactions with drugs, and are emphasized with a distinctive icon. Updated Drug Overview tables are enhanced with color as well as Top 100 icons that highlight the most commonly prescribed drugs.

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