treatment refractory schizophrenia a clinical conundrum

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Treatment Refractory Schizophrenia

Author : Peter F. Buckley
ISBN : 9783642452574
Genre : Medical
File Size : 32. 33 MB
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Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care. In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.

Schizophrenia Advances And Current Management An Issue Of Psychiatric Clinics Of North America

Author : Peter F. Buckley
ISBN : 9780323446334
Genre : Medical
File Size : 57. 54 MB
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This issue of the Psychiatric Clinics, edited by Dr. Peter F. Buckley, examines advances and current management in the treatment of Schizophrenia. The topics covered in this issue include, but are not limited to: Duration of Untreated Psychosis (DUP) and Longitudinal Perspectives on DUP; Neuroinflammation and Schizophrenia; Emerging Treatments for Schizophrenia; Treatment-Resistant Schizophrenia; Comorbidities and Schizophrenia; Recovery from Schizophrenia; and the latest in schizophrenia research.

Care Of The Mentally Disordered Offender In The Community

Author : Alec Buchanan
ISBN : 9780198804567
Genre : Medical
File Size : 70. 21 MB
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The thoroughly revised second edition of Care of the Mentally Disordered Offender in the Community is a comprehensive, evidence-based guide to the latest developments in the social context, management, and treatment of offenders in mental health care. In recent years there has been significant changes in the public perception of crime and the mentally ill offender, enhanced by research into causal links between violence and mental illness, and the increased publicity of the risk mentally disordered offenders could pose to the community. These, and other various factors, have significantly increased service development and research into psychological and pharmacological treatments and the rate of re-offending. Over three sections this essential guide explores key topics for discussion in the field. Part One critically examines the social, administrative and clinical context within which care is given in the modern day. Part Two discusses treatment and the evaluation of risk when determining the most appropriate treatment, whilst Part Three explores psychiatric services and their relationship with other agencies. Fully updated to ensure new areas for discussion are included, this book includes new chapters on relevant debates in the field such as US provision for the mentally disordered leaving prison, community management of sexual offending, the relationships between care and coercion, and the treatment of personality disorders. Written and edited by a global team of experts in the field, this book provides readers with useful insight into the social, clinical, and institutional contexts of this complex and relevant issue.

Complex Clinical Conundrums In Psychiatry

Author : Kuppuswami Shivakumar
ISBN : 9783319703114
Genre : Medical
File Size : 54. 95 MB
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This book provides the readers with a series of complex cases that are organized by psychiatric disorder. Written by experts in the field, the cases offer insight on how to navigate care in delicate situations while considering preexisting medical conditions. Topics cover pharmacological concerns in women who are pregnant or nursing, working with dementia patients suffering from HIV, assessing and treating ADHD in special populations, monitoring medication use in patience recovering from Substance Use Disorder, and working with patients suffering from personality disorders. Each chapter offers guidance through the maze of classifications, clinical features, diagnosis and various complex interventions. The book also covers new information on the advances in research and management aspects. Complex Clinical Conundrums in Psychiatry is a valuable resource for psychiatrists, psychologists, family physicians, geriatricians, counselors, social workers, nurses, and all medical professionals working with complex psychiatric patients.

Essential Papers On Object Relations

Author : Peter Buckley
ISBN : 9780814710807
Genre : Psychology
File Size : 45. 47 MB
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Genomics Circuits And Pathways In Clinical Neuropsychiatry

Author : Thomas Lehner
ISBN : 9780128005309
Genre : Science
File Size : 72. 94 MB
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This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

In Vivo Atlas Of Deep Brain Structures

Author : S. Lucerna
ISBN : 9783642563812
Genre : Medical
File Size : 54. 54 MB
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This 'in vivo' atlas contains more than 50 magnetic resonance (MR) images of the brain. Each structure is represented in the axial, coronal and sagittal plane, magnified in colour schemes and reconstructed in 3D images with a useful millimetric scale. The atlas offers the reader a practical and simple tool for surgical planning and for diagnostic and anatomical studies. The high level of anatomical definition of the in vivo MR images means that there is no loss in precision as a result of post-mortem changes. No doubt, this book is an excellent teaching instrument for all students of the neurosciences, regardless of the individual level of training and expertise.

Guide To Assessment Scales In Schizophrenia

Author : Richard Keefe
ISBN : 9781908517715
Genre : Medical
File Size : 83. 22 MB
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This book provides a wealth of assessment instruments from the world’s experts to help clinicians gather the most important information from their patients. This is the 3rd edition of our highly successful guides to Rating Scales in Schizophrenia, it is a practical and quick reference publication for psychiatrists.

Current Schizophrenia

Author : Dieter Naber
ISBN : 9781908517685
Genre : Medical
File Size : 33. 60 MB
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Advances in pharmacotherapy and psychosocial interventions continue to improve the success of managing schizophrenia. Early detection and intervention in people with, or at risk for, psychosis give patients and their families hope for a better course of illness and an improved outcome. The interdisciplinary approach, combining pharmacotherapy and psychosocial interventions, markedly increases the chance of long-lasting remission and recovery. However, a cure for schizophrenia has yet to be found. Research, particularly in the past decade, has revealed some of the biological and genetic facets of the origins of schizophrenia, and this has contributed to the better quality of treatment. This book aims to provide a short but detailed overview of current standards of care in schizophrenia. It takes into consideration several treatment recommendations proposed in published guidelines for schizophrenia, including the guidelines by the National Institute for Health and Clinical Excellence (2009), the American Psychiatric Association (2004), the Canadian Psychiatric Association (2005), and the Royal Australian and New Zealand College of Psychiatrists (2005). A major problem with guidelines such as these is the difficulties encountered in translating them into daily clinical practice. Therefore, the fundamental aim of this book is to present the guidelines as clearly as possible in the context of relevant clinical treatment issues. The book does this with the help of figures that provide the clinician with algorithms and summaries of the most important information required for the practical treatment and theoretical understanding of schizophrenia.

Electroconvulsive Therapy In America

Author : Jonathan Sadowsky
ISBN : 9781315522845
Genre : History
File Size : 38. 53 MB
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Electroconvulsive Therapy is widely demonized or idealized. Some detractors consider its very use to be a human rights violation, while some promoters depict it as a miracle, the "penicillin of psychiatry." This book traces the American history of one of the most controversial procedures in medicine, and seeks to provide an explanation of why ECT has been so controversial, juxtaposing evidence from clinical science, personal memoir, and popular culture. Contextualizing the controversies about ECT, instead of simply engaging in them, makes the history of ECT more richly revealing of wider changes in culture and medicine. It shows that the application of electricity to the brain to treat illness is not only a physiological event, but also one embedded in culturally patterned beliefs about the human body, the meaning of sickness, and medical authority.

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