antibacterial agents chemistry mode of action mechanisms of resistance and clinical applications

Download Book Antibacterial Agents Chemistry Mode Of Action Mechanisms Of Resistance And Clinical Applications in PDF format. You can Read Online Antibacterial Agents Chemistry Mode Of Action Mechanisms Of Resistance And Clinical Applications here in PDF, EPUB, Mobi or Docx formats.

Antibacterial Agents

Author : Rosaleen Anderson
ISBN : 9781118325445
Genre : Science
File Size : 49. 50 MB
Format : PDF, Kindle
Download : 902
Read : 601

Get This Book


Antibacterial agents act against bacterial infection either bykilling the bacterium or by arresting its growth. They do this bytargeting bacterial DNA and its associated processes, attackingbacterial metabolic processes including protein synthesis, orinterfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this importantclass of chemotherapeutic drugs. Compounds are organised accordingto their target, which helps the reader understand the mechanism ofaction of these drugs and how resistance can arise. The book usesan integrated “lab-to-clinic” approach which coversdrug discovery, source or synthesis, mode of action, mechanisms ofresistance, clinical aspects (including links to currentguidelines, significant drug interactions, cautions andcontraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazoleantibacterial agents agents targeting metabolic processes - sulfonamideantibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolideand tetracycline antibiotics, chloramphenicol, andoxazolidinones agents targeting cell wall synthesis - β-Lactam andglycopeptide antibiotics, cycloserine, isonaizid, anddaptomycin Antibacterial Agents will find a place on the bookshelvesof students of pharmacy, pharmacology, pharmaceutical sciences,drug design/discovery, and medicinal chemistry, and as a benchreference for pharmacists and pharmaceutical researchers inacademia and industry.

Novel Antimicrobial Agents And Strategies

Author : David A. Phoenix
ISBN : 9783527676156
Genre : Medical
File Size : 59. 69 MB
Format : PDF, Docs
Download : 180
Read : 670

Get This Book


By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broad spectrum of current and potential antimicrobial medications and treatments. The result is a comprehensive survey ranging from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, from metallic nanoparticles to photo- and sonosensitizers and to phage therapy. In each case, the therapeutic approaches are compared in terms of their mechanisms, likelihood to induce resistance, and their efficiency in a global healthcare context. Unrivaled knowledge for professionals in fundamental research, pharmaceutical development and clinical practice.

Antibiotics

Author : Claudio O. Gualerzi
ISBN : 9783527659708
Genre : Medical
File Size : 85. 34 MB
Format : PDF
Download : 109
Read : 484

Get This Book


Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.

Molecular Diagnostics

Author : Lela Buckingham
ISBN : 9780803699540
Genre : Medical
File Size : 41. 46 MB
Format : PDF, ePub, Mobi
Download : 379
Read : 455

Get This Book


Meet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today’s laboratories. With a focus on the application of molecular concepts to the diagnosis of disease, the 3rd Edition of this popular resource encompasses microbiology, virology, genetics, oncology, and human identification.

Small Animal Clinical Pharmacology And Therapeutics E Book

Author : Dawn Merton Boothe
ISBN : 9781437723571
Genre : Medical
File Size : 76. 1 MB
Format : PDF, ePub
Download : 671
Read : 647

Get This Book


Confidently utilize the rapidly growing selection of pharmaceuticals used to treat small animals. Small Animal Pharmacology and Therapeutics, 2nd Edition helps you understand both the therapeutic uses of common pharmaceuticals and the pharmacology behind them, giving you all of the information you need to design and modify dosing regimens, identify factors that cause drugs to fail, and anticipate adverse drug reactions. Comprehensive approach emphasizes the use of drugs for prevention as well as treatment. Clear, consistent organization makes it easy to find the information you need when you need it. Dosage tables help you find essential pharmaceutical information at a glance. Pharmacogenetics chapter helps you understand how to use this emerging science to find the right dose for each patient, optimizing efficiency and minimizing toxicity. Routes of administration and sample pharmaceutical calculations provide fast, efficient access to comprehensive drug administration all in one inclusive resource. Multiple chapters on Antimicrobial Drugs and Antimicrobial Therapy highlight the impact of antimicrobial resistance on current practice.

Macrolide Antibiotics

Author : Satoshi Ōmura
ISBN : 0125264518
Genre : Medical
File Size : 63. 17 MB
Format : PDF, ePub, Docs
Download : 852
Read : 1131

Get This Book


Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.

Antibiotics In Laboratory Medicine

Author : Victor Lorian
ISBN : 0781749832
Genre : Medical
File Size : 81. 24 MB
Format : PDF
Download : 577
Read : 1277

Get This Book


Implement the most current science and practice in antimicrobial research. Now, find the newest approaches for evaluating the activity, mechanisms of action, and bacterial resistance to antibiotics with this completely updated, landmark reference. Turn to this comprehensive reference for groundbreaking evidence on the molecular link between chemical disinfectants, sterilants, and antibiotics. On the latest methods for detecting antibacterial resistance genes in the clinical laboratory, and antivirogram use to select the most active antiviral components against your patient's HIV.

Annual Reports In Medicinal Chemistry

Author :
ISBN : 0080583636
Genre : Medical
File Size : 90. 63 MB
Format : PDF, Docs
Download : 133
Read : 689

Get This Book


Annual Reports in Medicinal Chemistry

Carranza S Clinical Periodontology

Author : Michael G. Newman
ISBN : 9781455706389
Genre : Medical
File Size : 33. 59 MB
Format : PDF, ePub
Download : 223
Read : 625

Get This Book


The most widely used periodontics text, Carranza's Clinical Periodontology provides both print and online access to basic procedures as well as the latest in advanced procedures and techniques in reconstructive, esthetic, and implant therapy. Not only does this book show how to do periodontal procedures, it describes how to best manage the outcomes and explains the evidence supporting each treatment. Written by leading experts Michael Newman, Henry Takei, Perry Klokkevold, and Fermin Carranza, along with a pool of international contributors, this edition also discusses the close connection between oral health and systemic disease. A new Expert Consult website includes the entire, fully searchable contents of the book, and takes learning to a whole new level with content updates, videos, a drug database, and much more. Comprehensive coverage describes all aspects of periodontics in a single volume, including periodontal pathology, the etiology of periodontal diseases, the relationship between periodontal disease and systemic health, treatment of periodontal diseases, oral implantology, supportive treatment, and ethics, legal, and practical matters. Problem-solving, scenario-based learning opportunities use well-documented case reports to help you learn both basic and advanced procedures and techniques. 'Speed to competence' is enhanced with access to print, online, and mobile platforms. A unique approach combines evidence-based decision-making, science transfer, and classification/nomenclature throughout every chapter. A one-of-a-kind Genetic Factors and Periodontal Disease chapter examines the role of genetic factors in gum disease. In-depth information serves as an excellent foundation in preparing for the National Board Dental Exam. Expert Consult website offers fast, reliable online access to advanced material, videos, an image collection, a drug database, interactive flash cards, multiple-choice test questions, interactive references, and Pathology Consult -- plus, the entire contents of the book are fully searchable. Find core information in the book; additional, advanced information is provided online. Consult your book from any computer, anywhere in the world, for the entire life of this edition. Keep current with regular updates of the latest periodontal news and information. Follow links from biographical citations to the corresponding MEDLINE abstracts. See a comprehensive library of pathology photos. Coverage of the latest advances includes the emerging link between periodontal disease and systemic health. Full-color illustrations depict the newest developments in surgical technology. A new Multidisciplinary Approach to Dental and Periodontal Problems chapter discusses the importance of collaborative care in the practice of periodontics. Etiology of Periodontal Diseases (Part 4) provides a more comprehensive background in periodontal anatomy, physiology, and pathogenesis.

Infectious Diseases Of The Fetus And Newborn E Book

Author : Christopher B. Wilson
ISBN : 9781437736373
Genre : Medical
File Size : 68. 82 MB
Format : PDF, ePub, Docs
Download : 994
Read : 987

Get This Book


Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 7th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization of the fetus/mother. Nationally and internationally recognized in immunology and infectious diseases, new associate editors Nizet and Maldonado bring new insight and fresh perspective to the book. Get the latest information on maternal infections when they are pertinent to the infant or developing fetus, including disease transmission through breastfeeding Diagnose, prevent, and treat neonatal infectious diseases with expert guidance from the world's leading authorities and evidence-based recommendations. Incorporate the latest findings about infections found in utero, during delivery, and in the neonatal period. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format Get fresh perspectives from two new associate editors—Drs. Yvonne Maldonado, head of the Pediatric Infectious Disease program at Stanford, and Victor Nizet, Professor of Pediatrics & Pharmacy at University of California, San Diego and UCSD School of Medicine. Keep up with the most relevant topics in fetal/neonatal infectious disease including new antimicrobial agents, gram- negative infections and their management, and recommendations for immunization of the fetus/mother. Overcome the clinical challenges in developing countries where access to proper medical care is limited. Apply the latest recommendations for H1N1 virus and vaccines. Identify and treat infections with the latest evidence-based information on fighting life-threatening diseases in the fetus and newborn infants.

Top Download:

Best Books