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Advances In Cancer Research

Author :
ISBN : 9780124016835
Genre : Science
File Size : 85. 14 MB
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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers AEG-1/MTDH/Lyric implicated in multiple human cancers. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Advances In Cancer Research

Author : George F. Vande Woude
ISBN : 0120066769
Genre : Medical
File Size : 77. 90 MB
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Volume 76 of Advances in Cancer Research continues the series' goal of publishing timely and authoritative reviews in the broad field of cancer research. Ruoslahti begins the volume with a review of fibronectin and its integrin receptors in cancer. Chapter 2 by Ganter and Lipsick discusses Myb and oncogenesis. Biscardi and colleagues present their research on c-Src, receptor tyrosine kinases, and human cancer in Chapter 3. Chapter 4 by Schulz covers epidemiology of Kaposi's sarcoma and associated herpesvirus/human herpesvirus 8. The consensus on synergism between cigarette smoke and other environmental carcinogens in the causation of lung cancer is reviewed by Reif and Heeren in Chapter 5. In Chapter 6, Breivik and Gaudernack discuss perspectives on carcinogenesis and natural selection in the genetics and epigenetics of colorectal cancer. Chapter 7 by Coulie and co-workers concludes the volume with a discussion of anti-tumor immunity at work in a melanoma patient.

A Review Of The Department Of Defense S Program For Breast Cancer Research

Author : Institute of Medicine
ISBN : 0309174562
Genre : Medical
File Size : 90. 97 MB
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According to current statistical data, one in eight women will be diagnosed with breast cancer. The five-year survival rate for breast cancer patients has improved in recent years, but the overall mortality rates have changed little. In 1993 Congress allocated $210 million for breast cancer research as part of the Department of Defense budget. An Institute of Medicine (IOM) committee was convened at that time to advise the U.S. Army Medical Research and Development Command on strategies for managing a breast cancer research program. This book evaluates the program's management and achievements to date. Although it is too early to evaluate the program in terms of breakthrough results and new insights produced by the funded projects or investigators, this book documents the process used to select research proposals for funding and analyzes the portfolio of funded projects in terms of their responsiveness to the recommendations and fundamental questions articulated in the 1993 IOM report.

An Omics Perspective On Cancer Research

Author : William C.S. Cho
ISBN : 9048126754
Genre : Medical
File Size : 36. 53 MB
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Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality will provide a knowledge base which changes the face of cancer understanding and therapeutics. This is the first book to provide such a comprehensive coverage of a rapidly evolving area written by leading experts in the field of omics. It complies and details cutting-edge cancer research that covers the broad advances in the field and its application from cancer-associated gene discovery to drug target validation. It also highlights the potential of using integration approach for cancer research. This unique and timely book provides a thorough overview of developing omics, which will appeal to anyone involved in cancer research. It will be a useful reference book for graduate students of different subjects (medicine, biology, engineering, etc) and senior scientists interested in the fascinating area of advanced technologies in cancer research. Readership: This is a precious book for all types of readers – cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, pharmaceutical specialists, biostatisticians, and bioinformaticists who want to expand their knowledge in cancer research.

Trends In Cervical Cancer Research

Author : Hector T. Varaj
ISBN : 1600212999
Genre : Medical
File Size : 71. 36 MB
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Cervical cancer is a malignancy of the cervix. World-wide, it is the second most common cancer of women. It may present with vaginal bleeding but symptoms may be absent until the cancer is in advanced stages, which has made cervical cancer the focus of intense screening efforts utilising the Pap smear. Most scientific studies point to human papillomavirus (HPV) infection which is responsible for 90% of the cases of cervical cancer. There are 7 most common types of HPV-16, 18, 31, 33, 42, 52 and 58. Types 16 and 18 being the most common cause of the cancer. Treatment is with surgery (including local excision) in early stages and chemotherapy and radiotherapy in advanced stages of the disease. This book presents cutting edge research in this study of cervical cancer. This involves, new perspectives in pharmacological treatments, anti-hormonal agents, therapeutic trends for patients, nerve sparing treatments, antibodies in single chain formats, predictors of radiation response, lymphatic mapping and docetaxel labelling with radionuclides.

Trends In Prostate Cancer Research

Author : John N. Lucas
ISBN : 1594542651
Genre : Medical
File Size : 67. 1 MB
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Prostate cancer is the most common type of cancer in men (other than skin cancer). Of all the men who are diagnosed with cancer each year, more than one-fourth have prostate cancer. This book includes within its scope the prevention, risk factors, symptoms, diagnosis, treatment, and rehabilitation of prostate cancer. Leading-edge scientific research from throughout the world is presented.

Yeast As A Tool In Cancer Research

Author : John L Nitiss
ISBN : 9781402059636
Genre : Medical
File Size : 33. 42 MB
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Leland H. Hartwell Director, Fred Hutchinson Cancer Research Center, Nobel Laureate for Medicine, 2001 Yeast has proved to be the most useful single-celled organism for studying the fundamental aspects of cell biology. Resources are now available for yeast that greatly simplify and empower new investigations, like the presence of strains with each gene deleted, each protein tagged and databases on protein–protein interactions, gene regulation, and subcellular protein location. A powerful combination of genetics, cell biology, and biochemistry employed by thousands of yeast researchers has unraveled the complexities of numerous cellular processes from mitosis to secretion and even uncovered new insights into prion diseases and the role of prions in normal biology. These insights have proven, time and again, to foretell the roles of proteins and pathways in human cells. The collection of articles in this volume explores the use of yeast in pathway analysis and drug discovery. Yeast has, of course, supplied mankind’s most ubiquitous drug for thousands of years. In one aspect, the role of yeast in drug discovery is much like the role of yeast in other areas of biology. Yeast offers the power of genetics and a repetoire of resources available in no other organism. Using yeast in the study of drug targets and metabolism can help to make a science of what has been largely an empirical activity. A science of drug discovery would permit rigorous answers to important questions.

Progress In Oral Cancer Research

Author : Frederik L. Nielsen
ISBN : 1600218652
Genre : Medical
File Size : 63. 97 MB
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Oral cancer is any cancerous tissue growth located in the mouth. It may arise as a primary lesion originating in any of the oral tissues, by metastasis from a distant site of origin, or by extension from a neighbouring anatomic structure, such as the nasal cavity or the maxillary sinus. Oral cancers may originate in any of the tissues of the mouth, and may be of varied histologic types: teratoma, adenocarcinoma derived from a major or minor salivary gland, lymphoma from tonsillar or other lymphoid tissue, or melanoma from the pigment producing cells of the oral mucosa. Far and away the most common oral cancer is squamous cell carcinoma, originating in the tissues that line the mouth and lips. Oral or mouth cancer most commonly involves the tissue of the lips or the tongue. It may also occur on the floor of the mouth, cheek lining, gingiva (gums), or palate (roof of the mouth). Most oral cancers look very similar under the microscope and are called squamous cell carcinoma. These are malignant and tend to spread rapidly. This book presents important new research in the field.

New Developments In Cancer Research

Author : Lee P. Jeffries
ISBN : 160021102X
Genre : Medical
File Size : 40. 76 MB
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Cancer is a group of different diseases (over 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. If a cancer spreads (metastasizes), the new tumour bears the same name as the original (primary) tumour. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures which establish hope for wide-spread cures. The book brings together important research from around the world in this frontal field.

Cancer Research

Author :
ISBN : CORNELL:31924108296363
Genre : Cancer
File Size : 52. 22 MB
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