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An Elegant Defense

Author : Matt Richtel
ISBN : 9780062698506
Genre : Science
File Size : 85. 9 MB
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National Bestseller “One of those rare nonfiction books that transcends the genre. ... Extraordinary.” —Douglas Preston, New York Times bestselling author of The Lost City of the Monkey God A grand tour of the human immune system and the secrets of health, by the Pulitzer Prize–winning New York Times journalist A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before. The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats. For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders. Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance. Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

Summary Study Guide An Elegant Defense

Author : Lee Tang
ISBN : 9781091397279
Genre : Health & Fitness
File Size : 87. 32 MB
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A Comprehensive Primer on the Human Immune System The must-read summary of “An Elegant Defense: The Extraordinary New Science of the Immune System,” by Matt Richtel. The immune system defends people against germs and microorganisms every day. In most cases, it does a great job of keeping people healthy and preventing infections. But it can easily be compromised by fatigue, stress, toxins, advanced age, and poor nutrition. Problems with the immune system can lead to illness and infection. An unchecked immune system can attack the body's own cells and damage its own organs. Scientists call it autoimmunity, which affects 20 percent of Americans. This book tells you the story of how scientists: * Discover things like T cells and B cells. * Apply their knowledge through life-saving vaccines and transplants. * Delve into the tiny fragments of the immune system and build a blueprint of the machine. * Build medicines by replicating the defense cells. Read this book to better understand one of the enduring mysteries of human biology. This guide includes: * Book Summary—helps you understand the key concepts. * Online Videos—covers the concepts in more depth. Value-added from this guide: * Save time * Understand key concepts * Expand your knowledge

Apolog A De Un Matem Tico

Author : Godfrey Harold Hardy
ISBN : 9788412090628
Genre : Mathematics
File Size : 63. 53 MB
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G.H. Hardy fue uno de los mejores matemáticos de este siglo, reconocido entre sus contemporáneos como un "matemático auténtico, el más puro entre los puros". Esta Apología, escrita emotivamente cuando su poder creativo matemático estaba ya en su ocaso, es un relato brillante y cautivador de las matemáticas consideradas como mucho más que una ciencia, que nos proporciona una de las mejores visiones de cómo discurre la mente de un matemático en pleno proceso de trabajo. De hecho, este libro está ampliamente considerado como una de las mejores penetraciones en la mente de un matemático profesional, escrita para profanos. En sus páginas, Hardy defiende el valor de la matemática teórica más abstracta y la belleza como valor indispensable de las buenas teorías matemáticas por encima de otros valores como su aplicabilidad o relevancia para los problemas de física. Cuando fue publicada en inglés por primera vez, Graham Greene la aclamó, junto con los cuadernos de notas de Henry James, como "la mejor narración de lo que representa el ser un artista creativo". El prólogo de C. P. Snow a la edición inglesa proporciona algunas claves de la vida de Hardy, incluyendo las anécdotas relativas a su colaboración con el matemático indio Ramanujan, sus aforismos y su pasión por el críquet. Este es un relato único de la fascinación por las matemáticas y de uno de sus exponentes más convincentes de los tiempos modernos.

A Communitarian Defense Of Liberalism

Author : Mark S. Cladis
ISBN : 9780804723657
Genre : Philosophy
File Size : 35. 78 MB
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In this provocative and timely reading of Emile Durkheim the author isolates the merits and liabilities of both liberal and communitarian theories and demonstrates that we need not be in the position of having to choose between them.

House Documents

Author : USA House of Representatives
ISBN : BSB:BSB11037533
Genre :
File Size : 56. 42 MB
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Congressional Series Of United States Public Documents

Author :
ISBN : UCAL:B3985133
Genre :
File Size : 29. 57 MB
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Consciousness And Meaning

Author : Brian Loar
ISBN : 9780191669002
Genre : Philosophy
File Size : 82. 32 MB
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One of the most important problems of modern philosophy concerns the place of the mind — and, in particular, of consciousness, meaning, and intentionality — in a physical universe. Brian Loar was a major contributor to the discussion of this problem for over four decades. This volume has two parts: one a selection of Loar's essays on the philosophy of language, the other on the philosophy of mind. A common thread in Loar's essays on language is his engagement with the Gricean program of analyzing linguistic representation in terms of mental representation, thus reducing the semantic to the psychological. In the philosophy of mind he was concerned with understanding consciousness and intentionality (mental representation) from the subjective perspective. The concern that unifies Loar's work in mind and language is how to understand subjectivity in a physical universe. He was committed to the reality of phenomenology, qualia, and the subjective perspective; and he found that phenomena like intentionality and consciousness are, in a certain sense, ineliminable and irreducible to objective ones. At the same time he believed that intentionality and consciousness are grounded in the physical. One of his great contributions was to reconcile these two positions by being a conceptual and explanatory anti-reductionist about both consciousness and intentionality but a metaphysical reductionist nonetheless. He had a deep commitment both to physicalism and to the reality and significance of the subjective point of view.

When Presidents Lie

Author : Eric Alterman
ISBN : 1101158875
Genre : Political Science
File Size : 31. 57 MB
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“I’ve never read a better explanation of why presidents lie.”—John W. Dean, former counsel to President Nixon, The Washington Monthly By the end of the twentieth century, after decades of demoralizing revelations about the mendacity of their elected officials, most Americans had come to accept the fact that deception was not only an accepted practice in government but also pervasive. Whatever the reasons proposed to justify falsehoods—practicality, expediency, extraordinary conditions of wartime—the ability to lie convincingly had come to be regarded as almost being a qualification for holding public office. Although such behavior has come to be tolerated, little accounting has been taken of the effects of this institutionalized dishonesty in our political culture. When Presidents Lie: A History of Official Deception and Its Consequences addresses its subject not from a moral perspective, but from a pragmatic one, and discovers that in the end, honesty in government is, in fact, the best policy. Journalist and historian Eric Alterman’s meticulous research is drawn from primary-source materials, both government documents and the media reactions to the unfolding dramas, and demonstrates how these lies returned to haunt their tellers, or their successors, destroying the very policy the lie had been intended to support. Without exception, each of the presidents paid a high price for deception. So, too, did the nation. This is history at its most compelling, a balanced, eloquent, and revelatory chronicle of presidential dishonesty and its incalculable costs. In the fundamental questions it raises about leadership, accountability, and democracy, it is required reading for anyone who is concerned about America’s past—or her future.

Thinking About America S Defense

Author : Glenn A. Kent
ISBN : 9780833048622
Genre : Technology & Engineering
File Size : 50. 13 MB
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Lieutenant General Glenn A. Kent was a uniquely acute analyst and developer of American defense policy in the second half of the twentieth century. His 33-year career in the Air Force was followed by more than 20 years as one of the leading analysts at RAND. This volume is not a memoir in the normal sense but rather a summary of the dozens of national security issues in which Glenn was personally engaged over the course of his career. These issues included creating the single integrated operational plan (SIOP), leading DoD's official assessment of strategic defenses in the 1960s, developing and analyzing strategic nuclear arms control agreements, helping to bring new weapon systems to life, and many others. Each vignette describes the analytical frameworks and, where appropriate, the mathematical formulas and charts that Glenn developed and applied to gain insights into the issue at hand. The author also relates his roles in much of the bureaucratic pulling and hauling that occurred as issues were addressed within the government.

Congressional Serial Set

Author :
ISBN : UCLA:L0063599823
Genre : United States
File Size : 22. 77 MB
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