handbook of hidden markov models in bioinformatics chapman hall crc mathematical and computational biology

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Handbook Of Hidden Markov Models In Bioinformatics

Author : Martin Gollery
ISBN : 9781420011807
Genre : Science
File Size : 88. 59 MB
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Demonstrating that many useful resources, such as databases, can benefit most bioinformatics projects, the Handbook of Hidden Markov Models in Bioinformatics focuses on how to choose and use various methods and programs available for hidden Markov models (HMMs). The book begins with discussions on key HMM and related profile methods, including the HMMER package, the sequence analysis method (SAM), and the PSI-BLAST algorithm. It then provides detailed information about various types of publicly available HMM databases, such as Pfam, PANTHER, COG, and metaSHARK. After outlining ways to develop and use an automated bioinformatics workflow, the author describes how to make custom HMM databases using HMMER, SAM, and PSI-BLAST. He also helps you select the right program to speed up searches. The final chapter explores several applications of HMM methods, including predictions of subcellular localization, posttranslational modification, and binding site. By learning how to effectively use the databases and methods presented in this handbook, you will be able to efficiently identify features of biological interest in your data.

Gene Expression Studies Using Affymetrix Microarrays

Author : Hinrich Gohlmann
ISBN : 1420065165
Genre : Science
File Size : 75. 45 MB
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The Affymetrix GeneChip® system is one of the most widely adapted microarray platforms. However, due to the overwhelming amount of information available, many Affymetrix users tend to stick to the default analysis settings and may end up drawing sub-optimal conclusions. Written by a molecular biologist and a biostatistician with a combined decade of experience in practical expression profiling experiments and data analyses, Gene Expression Studies Using Affymetrix Microarrays tears down the omnipresent language barriers among molecular biology, bioinformatics, and biostatistics by explaining the entire process of a gene expression study from conception to conclusion. Truly Multidisciplinary: Merges Molecular Biology, Bioinformatics, and Biostatistics This authoritative resource covers important technical and statistical pitfalls and problems, helping not only to explain concepts outside the domain of researchers, but to provide additional guidance in their field of expertise. The book also describes technical and statistical methods conceptually with illustrative, full-color examples, enabling those inexperienced with gene expression studies to grasp the basic principles. Gene Expression Studies Using Affymetrix Microarrays provides novices with a detailed, yet focused introductory course and practical user guide. Specialized experts will also find it useful as a translation dictionary to understand other involved disciplines or to get a broader picture of microarray gene expression studies in general. Although focusing on Affymetrix gene expression, this globally relevant guide covers topics that are equally useful for other microarray platforms and other Affymetrix applications.

Encyclopedia Of Bioinformatics And Computational Biology

Author :
ISBN : 9780128114322
Genre : Medical
File Size : 87. 51 MB
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Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Structural Bioinformatics

Author : F. J. Burkowski
ISBN : STANFORD:36105131640844
Genre : Computers
File Size : 24. 95 MB
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As the field of bioinformatics grows, the progression of topics in the field reflects separate concerns for sequence data and structure data. This book presents key algorithms - some developed within the artificial intelligence community - and their applications to problems in structural biology and drug discovery.

Syntactic Pattern Recognition

Author : Flasinski Mariusz
ISBN : 9789813278486
Genre : Computers
File Size : 55. 93 MB
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This unique compendium presents the major methods of recognition and learning used in syntactic pattern recognition from the 1960s till 2018. Each method is introduced firstly in a formal way. Then, it is explained with the help of examples and its algorithms are described in a pseudocode. The survey of the applications contains more than 1,000 sources published since the 1960s. The open problems in the field, the challenges and the determinants of the future development of syntactic pattern recognition are discussed.This must-have volume provides a good read and serves as an excellent source of reference materials for researchers, academics, and postgraduate students in the fields of pattern recognition, machine perception, computer vision and artificial intelligence.

Biochemical Pathways

Author : Gerhard Michal
ISBN : 3860252399
Genre : Biochemistry
File Size : 43. 19 MB
Format : PDF, ePub
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Auf der Grundlage der weltbekannten "Biochemical Pathways," des "Boehringer-Posters," entstand dieses Buch. BeitrAge renommierter Wissenschaftler behandeln sAmtliche relevanten Themen aus dem Bereich Biochemie/Molekularbiologie auf dem aktuellen Stand der Forschung. Eine Vielzahl 6-farbiger (!) Grafiken veranschaulicht die A1/4beraus komplexen biochemischen VorgAnge. Damit schlAgt das Buch eine BrA1/4cke zwischen Lehrbuchstoff und Originalliteratur: als wertvolles Nachschlagewerk, als Aoeberblick A1/4ber die ZusammenhAnge in einem hAchst dynamischen Gebiet - eine Fundgrube fA1/4r alle, die in den Biowissenschaften auf dem Laufenden bleiben mA1/4ssen. Aoeber 1 Million mal wurde das sog. "Boehringer Poster," eine Aoebersicht A1/4ber die gesamte Biochemie, verkauft. Jetzt liegt das Material - natA1/4rlich komplett A1/4berarbeitet und aktualisiert - als benutzerfreundliches Buch vor.

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