inhalation studies foundations and techniques

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Inhalation Studies

Author : Robert F. Phalen
ISBN : 9780849314001
Genre : Medical
File Size : 22. 36 MB
Format : PDF
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This significantly updated and expanded new edition presents the scientific foundations of inhalation research essential to the design and conduct of toxicologic studies. It incorporates the major advances that have been made in the field, including recent advances in biology and the rapidly increasing global concerns and studies on particulate air pollution. The Second Edition was motivated by: new developments in the ultrafine particle health effects and concentrated aerosol research advances in understanding postnatal lung growth and the deposition and clearance of inhaled particles new techniques in toxicity testing the explosion of knowledge in the genetic and molecular realms the introduction of a large number of transgenic animal models updated ethical guidelines for animal testing the emergence of aerosol medicine the growing threat of aerosol-related terrorism increased appreciation of nonpulmonary effects of inhaled substances use of medical scanning techniques to study respiratory tract structure the introduction of new inhalation exposure systems the emergence of aerosol concentrators for use in air pollution studies

The Particulate Air Pollution Controversy

Author : Robert F. Phalen
ISBN : 1402072252
Genre : Medical
File Size : 66. 45 MB
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This concise book presents the relevant scientific data, historical developments, unsolved problems, and new research opportunities related to particulate air pollution and human health. Included are chapters on the nature of particulate air pollution, fates and toxicity of inhaled particles, evidence of harmful effects of air pollution, events that led to the current controversy, interpretation of modern epidemiology studies, needed research, challenges to commonly accepted ideas about pollutants and health, and recommendations for scientists, regulators, legislators, the public and industry.

Introduction To Air Pollution Science

Author : Robert F. Phalen
ISBN : 9780763780449
Genre : Medical
File Size : 57. 18 MB
Format : PDF, Kindle
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This unique textbook examines the basic health and environmental issues associated with air pollution including the relevant toxicology and epidemiology. It provides a foundation for the sampling and analysis of air pollutants as well as an understanding of international air quality regulations. Written for upper-level undergraduate and introductory graduate courses in air pollution, the book is also a valuable desk reference for practicing professionals who need to have a broad understanding of the topic. Key features: - Provides the most up-to-date coverage of the basic health and environmental issues associated with air pollution. - Offers a broader examination of air pollution topics, beyond just the meteorological and engineering aspects of air pollution. - Includes the following Instructor Resources: Instructor's Manual, PowerPoint Presentations, and a TestBank. The Phalens have put together a timely book on a critically important topic that affects all of us -- air pollution – and they do so in a new and highly relevant way: they consider the broad societal health impacts from a fundamental science viewpoint. The epidemiology, toxicology, and risks of air pollutants are included, and ethical issues of concern are highlighted. This book is a must-read for students who wish to become professionals in the air quality field and for students of environmental science whose work includes air pollution issues. The book is a significant contribution to the discipline." - Cliff I. Davidson, Director, Center for Sustainable Engineering; Thomas C. and Colleen L. Wilmot Professor of Engineering, Syracuse Center of Excellence in Environmental and Energy Systems and Department of Civil and Environmental Engineering, Syracuse University "Truly, human well-being and public health in the 21st century may hinge on our ability to anticipate, recognize, evaluate, control, and confirm responsible management of air pollution. This timely, informative, and insightful text provides a solid introduction for students and a technically sound handbook for professionals seeking literacy and critical thinking, real-life examples, understanding (not just rote applications), opportunities for continuous improvement, and modern tools for assessing and managing current and evolving air pollution challenges." - Mark D. Hoover, PhD, CHP, CIH Aerosol and health science researcher, author, and editor

Methods In Inhalation Toxicology

Author : Robert F. Phalen
ISBN : 0849333431
Genre : Medical
File Size : 72. 75 MB
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Conducting studies of natural and man-made air contaminants is a specialized research activity that draws upon skills from a variety of disciplines including toxicology, pharmacology, industrial hygiene, and environmental health. Methods in Inhalation Toxicology describes how knowledge from these disciplines is integrated into the design and conduct of inhalation studies. Each of the vital aspects of conducting these studies is discussed in detail, including the use of animal subjects and the related quality control and ethical considerations, air purification methodology, exposure atmosphere generation and characterization, inhalation exposure systems, and real-time and post-exposure biological assessments. These methods will enable you to conduct inhalation studies, easily adding any specific measures of particular interest to your research. The book covers techniques needed to: provide suitable clean air for experiments correctly generate the particles and gases being studied select the proper exposure system monitor the exposure prepare tissues for study ensure that animals do not have confounding lung disease The helpful descriptions and detailed lists of suppliers of preferred equipment and materials will help you to perform valid, reproducible inhalation toxicology studies. Methods in Inhalation Toxicology is a perfect textbook for students in toxicology programs, as well as for scientists who conduct inhalation studies in both academic and industrial environments.

Inhalation Aerosols

Author : Anthony J. Hickey
ISBN : 1420002252
Genre : Medical
File Size : 30. 94 MB
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This unique reference integrates the theory and practical use of aerosols in inhalation therapy into a single resource-presenting the physical chemistry of formulation, the physics of aerosol generation, aerodynamic behavior, and therapeutic implications. Offers up-to-date techniques for droplet and particle generation, including air-blast and ultrasonic nebulizers, propellant-driven metered-dose inhalers, dry-powder inhalers, and elecctrospray systems!

Handbook Of Human Toxicology

Author : Edward J. Massaro
ISBN : 143980575X
Genre : Medical
File Size : 24. 38 MB
Format : PDF
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Covering some of the most important topics in modern toxicology, the Handbook of Human Toxicology is a unique and valuable addition to the current literature. It addresses issues, answers questions, and provides data related to. Within each of these five major sections are several carefully selected topics that reflect the current state of human toxicology. From tissue uptake of mercury to the effects of drugs on immune systems, the text provides much-needed information quickly and easily.

Energy Abstracts For Policy Analysis

Author : Holifield National Laboratory
ISBN : UOM:39015012048172
Genre : Power resources
File Size : 51. 25 MB
Format : PDF
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Concepts In Inhalation Toxicology

Author : Roger O. McClellan
ISBN : 1439805571
Genre : Medical
File Size : 69. 52 MB
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Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.

Handbook Of Toxicology

Author : Michael J. Derelanko
ISBN : 0849386683
Genre : Medical
File Size : 84. 54 MB
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This exciting and unique book contains practical reference information useful to practicing toxicologists in the chemical and pharmaceutical industries, contract laboratories, regulatory agencies, and academia. Each chapter begins with an outline of its contents. Text is purposely kept to a minimum-data is conveniently organized in tabular form for easy access. This valuable reference appeals to both experts and students alike.

Toxicology Of The Lung

Author : Donald E. Gardner
ISBN : 1560328010
Genre : Medical
File Size : 38. 28 MB
Format : PDF, Docs
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Thoroughly revised and updated, the third edition of Toxicology of the Lung brings together the latest accomplishments and advancements in concepts, approaches, and procedures now used to evaluate the risks associated with airborne contaminants. With chapters from leading authorities, including nine new chapters and a number of new topic areas, this edition describes how and why the lung and respiratory system respond as they do to toxicants and provides a clear understanding of human health risks associated with chemical exposure. This one-of-a-kind reference on inhalation toxicology will be invaluable to all professionals in academia, industry, clinics, research laboratories, and government agencies.

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